Quality Factors Influencing Consumer Demand for Small Fruit by Focus Group and Sensory Test

The market of berries is a niche of high value in Italy. Small fruit\u2019s healthy properties are well known in the international market, but little is known about the reason for a low commercialization rate of fresh small fruit in Italy. The objective of this study was to assess consumer preferences in Italy for selected berry species. Moreover, the study aims to identify the relevant attributes of berries that affect the demand for this produce according to consumers and to compare these attributes. We assessed relevant attributes affecting the demand for fresh berries for different consumers\u2019 profiles and compared berries\u2019 attributes rankings. The results reveal high concordance between blackberries and raspberries; price is the attribute that constrains more purchases because it is deemed too high. Consumers prefer small fruit because of the rising interest in their nutraceutical value, and they have a higher willingness to pay because of this important attribute

Low Power Analog Design in Scaled Technologies

In this paper an overview on the main issues in analog IC design in scaled CMOS technology is presented. Decreasing the length of MOS channel and the gate oxide has led to undoubted advantages in terms of chip area, speed and power consumption (mainly exploited in the digital parts). Besides, some drawbacks are introduced in term of power leakage and reliability. Moreover, the scaled technology lower supply voltage requirement has led analog designers to find new circuital solution to guarantee the required performance

Importance of food labeling as a mean of information and traceability according to consumers

Consumption patterns have considerably changed over recent years. We are witnessing more and more frequently to a lack of information (i.e. information asymmetry) between food producers and consumers, this generates in the consumer the latter need to access information related to processes of production of food and food distribution. Decision-making, in absence of further information, leads consumers to pay attention to food labeling. Food labels become the only tool for consumers to acquire additional information about products in order to make the purchase decision. In today’s modern and globalized market, labels limitations can be partially overcome by using Mobile Marketing tools, such as the QR Code (Quick Response Code). Therefore the objective of this study is: (1) categorize profiles of consumers accordingto the importance given to various information patterns shown on food labeling; (2) discover consumer behaviors when making a purchasing decision based on food information they require in the label; (3) discover consumer profiles with regards to food quality and the use QR Code to acquire further information about food products. Two Italian regional capitals were chosen, as representative of Northern and Southern Italy, basing on the geographical division of the Countrymade by the ISTAT (Istituto Nazionale di Statistica). The interviews were carried out by telephone, using a questionnaire. Data collected were processed by Multidimensional Scaling We discovered eight profiles of consumers with different purchasing behaviors. Some consumer profiles, with lifestyles typical of contemporary life, use the QR Code to obtain additional information about food products. The innovative purchasing behavior identifies a consumer who is particularly interested in food quality and safety. Agri-food businesses that focus on quality productions could target the innovative profile and communicate further information through the use of modern communication technologies

Soil carbon budget account for the sustainability improvement of a Mediterranean vineyard area

Sustainable viticulture is suggested as an interesting strategy for achieving the objectives of global greenhouse gas (GHG) emission reduction in terms of mitigation and adaptation. However, knowledge and quantification of the contribution of sustainable vineyard management on climate change impact are needed. Although it is widely assessed by several authors that the agricultural stage has a great impact in the wine chain, very few studies have evaluated the greenhouse gas emission in this phase including the ability of soil to sequester carbon (C) or the off-farm C loss by erosion. This work aimed to provide a vineyard carbon budget (vCB) tool to quantify the impact of grape production on GHG emission including the effects of environmental characteristics and agricultural practices. The vCB was estimated considering four different soil management scenarios: conventional tillage (CT), temporary cover crop with a leguminous species in alternate inter-rows (ACC), temporary cover crop with a leguminous species (CC), permanent cover crop (PCC). The estimation of vCB was applied at territory level in a viticulture area in Sicily (2468 ha of vineyard) using empirical data. Results of the present study showed that the environmental characteristics strongly affect the sustainability of vineyard management; the highest contribution to total CO2 emission is, in fact, given by the C losses by erosion in sloping vineyards. Soils of studied vineyards are a source of CO2 due to the low C inputs and high mineralization rate, except for soil managed by CC which can sequester soil C, contributing positively to vCB. The highest total CO2 emission was estimated in vineyards under CT management (2.31 t ha−1y−1), followed by CC (1.27 t ha−1y−1), ACC (0.69 t ha−1y−1) and PCC (0.64 t ha−1y−1). Findings of vCB applied at territory level highlighted the key role of the evaluation of carbon budget (CB) on a larger scale to identify the CO2 emission in relation to climatic and environmental factors. The present study could contribute to provide suggestions to policymakers and farmers for reducing GHG emissions and promote more sustainable grape production practices

Microparticles from patients with metabolic syndrome induce vascular hypo-reactivity via Fas/Fas-ligand pathway in mice

Peer reviewedPublisher PD

Progression of coronary calcification in healthy postmenopausal women

BACKGROUND: Coronary artery calcium score incrementally improves coronary risk prediction beyond that provided by conventional risk factors. Limited information is available regarding rates of progression of coronary calcification in women, particularly those with baseline scores above zero. Further, determinants of progression of coronary artery calcification in women are not well understood. This study prospectively evaluated rates and determinants of progression of coronary artery calcium score in a group of healthy postmenopausal women. METHODS: We determined coronary calcium score by computed tomography and recorded demographic, lifestyle and health characteristics of 914 postmenopausal women, a subset of those enrolled in the Women's Health Initiative Observational Study. The 305 women with calcium score ≥10 Agatston units at baseline were invited for repeat scan. This analysis includes the 94 women who underwent second scans. RESULTS: Mean age of study participants was 65 ± 9 years (mean ± SD), body mass index was 26.1 ± 6.1 kg/m(2), and baseline calcium score was 162 ± 220 Agatston units. Mean interval between scans was 3.3 ± 0.7 years. A wide range of changes in coronary calcium score was observed, from -53 to +452 Agatston units/year. Women with lower scores at baseline had smaller annual increases in absolute calcium score. Coronary calcium scores increased 11, 31 and 79 Agatston units/year among women with baseline calcium score in the lowest, middle and highest tertiles. In multivariate analysis, age was not an independent predictor of absolute change in coronary calcium score. Hydroxymethylglutaryl coenzyme A reductase inhibitor (statin) use at baseline was a negative predictor (p = 0.015), whereas baseline calcium score was a strong, positive predictor (p < 0.0001) of progression of coronary calcification. CONCLUSION: Among postmenopausal women with coronary calcium score ≥ 10 Agatston units, rates of change of coronary calcium score varied widely. In multivariate analysis, statin use was a negative independent determinant, whereas baseline calcium score was a strong positive predictor of annual change in coronary calcium score

HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production

BACKGROUND: Direct cellular contact with stimulated T cells is a potent mechanism that induces cytokine production in human monocytes in the absence of an infectious agent. This mechanism is likely to be relevant to T cell-mediated inflammatory diseases such as rheumatoid arthritis and multiple sclerosis. Microparticles (MP) generated by stimulated T cells (MPT) display similar monocyte activating ability to whole T cells, isolated T cell membranes, or solubilized T cell membranes. We previously demonstrated that high-density lipoproteins (HDL) inhibited T cell contact- and MPT-induced production of IL-1beta but not of its natural inhibitor, the secreted form of IL-1 receptor antagonist (sIL-1Ra). METHODOLOGY/PRINCIPAL FINDINGS: Labeled MPT were used to assess their interaction with monocytes and T lymphocytes by flow cytometry. Similarly, interactions of labeled HDL with monocytes and MPT were assessed by flow cytometry. In parallel, the MPT-induction of IL-1beta and sIL-1Ra production in human monocytes and the effect of HDL were assessed in cell cultures. The results show that MPT, but not MP generated by activated endothelial cells, bond monocytes to trigger cytokine production. MPT did not bind T cells. The inhibition of IL-1beta production by HDL correlated with the inhibition of MPT binding to monocytes. HDL interacted with MPT rather than with monocytes suggesting that they bound the activating factor(s) of T cell surface. Furthermore, prototypical pro-inflammatory cytokines and chemokines such as TNF, IL-6, IL-8, CCL3 and CCL4 displayed a pattern of production induced by MPT and inhibition by HDL similar to IL-1beta, whereas the production of CCL2, like that of sIL-1Ra, was not inhibited by HDL. CONCLUSIONS/SIGNIFICANCE: HDL inhibit both MPT binding to monocytes and the MPT-induced production of some but not all cytokines, shedding new light on the mechanism by which HDL display their anti-inflammatory functions

Synthesis, properties and water permeability of SWNT buckypapers

The ability of macrocyclic ligands to facilitate formation of dispersions of single-walled carbon nanotubes (SWNTs) was investigated using a combination of absorption spectrophotometry and optical microscopy. Vacuum filtration of aqueous dispersions containing SWNTs and various macrocyclic ligands (derivatised porphyrin, phthalocyanine, cyclodextrin and calixarene) afforded self-supporting membranes known as buckypapers. Microanalytical data and energy dispersive X-ray spectra were obtained for these buckypapers and provided evidence for retention of the macrocyclic ligands within the structure of the membranes. The electrical conductivities of the membranes varied between 30 ± 20 and 220 ± 60 S cm−1, while contact angle analysis revealed they all possessed hydrophilic surfaces. The mechanical properties of buckypapers prepared using macrocyclic ligands as dispersants were shown to be comparable to that of a benchmark material prepared using the surfactant Triton X-100 (Trix). Incorporation of the macrocyclic ligands into SWNT buckypapers was found to increase their permeability up to ten-fold compared to buckypapers prepared using Trix. No correlation was observed between the water permeability of the membranes and the average size of either their surface or internal pores. However, the water permeability of the membranes was found to be inversely dependent on their surface area

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes, represents an evolutionary link, and suggests essential functions of a dynamic extracellular vesicular compartment (including exosomes, microparticles or microvesicles and apoptotic bodies). Compelling evidence supports the significance of this compartment in a broad range of physiological and pathological processes. However, classification of membrane vesicles, protocols of their isolation and detection, molecular details of vesicular release, clearance and biological functions are still under intense investigation. Here, we give a comprehensive overview of extracellular vesicles. After discussing the technical pitfalls and potential artifacts of the rapidly emerging field, we compare results from meta-analyses of published proteomic studies on membrane vesicles. We also summarize clinical implications of membrane vesicles. Lessons from this compartment challenge current paradigms concerning the mechanisms of intercellular communication and immune regulation. Furthermore, its clinical implementation may open new perspectives in translational medicine both in diagnostics and therapy