483 research outputs found
Evolution of the Chinese shophouse facade in Malaysia: Manifestations of a diasporic people
The Chinese shophouse, in particular the traditional style of the pre-war period, is a unique residential-business built form common in major towns and cities in Southeast Asian countries, including Malaysia.This ubiquitous edifice was originally a built technology and concept of the Chinese immigrants that flocked to the Southern Seas in search for better prospects during the 19th century.The lives of the diasporic Chinese greatly intertwined with the shophouse – from daily living to commercial activities such as trading and business were all conducted within the
premise of the shophouse.The shophouse gained importance and started to evolve its façade
when the thriving Chinese emerged as wealthy middle-class that ultimately contributed to the
economic urbanization and development of major towns in Malaya.Under presiding trends,the plain unadorned shophouse façade transformed into ornate stylistic ornamentations that reflected an eclectic mix of Chinese, European and Malay cultural symbols and motifs.This essay examines the evolution of shophouse typology and façade during the late 19th- and early 20th -century Malaya. The shophouse’s evolving fa ade was a manifestation of the diasporic Chinese immigrant community that not only asserted their culture but celebrated eclecticism and hybridity in a pluralistic Malayan milieu.Employing qualitative research methods mainly utilizing visual materials (photographs) and in-depth interviews, this visual study discusses the cultural significations and symbolisms underneath the shophouse façade ornamentations, particularly the eclectic façade at its peak of evolution. Visual arts concepts such as ornamentation, visual semiotics, iconography and style, as well as cultural concepts like diaspora, eclecticism and hybridity are referred.At present, with modernization and skyscrapers changing the Malaysian urban landscape, many of these shophouses have ceased
importance and are now abandoned, defaced or destroyed.This study highlights the present critical scenario of a possible vanishing cultural heritage and recommends for necessary
shophouse conservation actions to be taken
Seri Rama and Maharaja Wana in Wayang Kulit Kelantan: Visual Analysis of Their Puppets
Wayang Kulit Kelantan, currently one of the two remaining shadow play forms in Malaysia, remains active in the northern part of peninsular Malaysia in particular the state of Kelantan, up till southern part of Thailand. It performs mainly a localized Malay folk version Hikayat Maharaja Wana derived from the famous Indian epic Ramayana, in contrast to the other literary version Hikayat Seri Rama.
The origin of Wayang Kulit Kelantan, although much has been debated, could have possibly derived from the pre-Islamic or archetypal prototype of Wayang Kulit Purwa of Java, following the Majapahit Empire’s collapse and the spread of Islam on that island in the 16th century (Ghulam-Sarwar, 2004, pp. 61-62). The introduction of the legendary nine saints (wali Songo) in Java (Ghulam-Sarwar, 1994, pp. 274-275) led to the migration of this proto shadow play from Java to Bali and other Indonesian islands as well as the Malay Peninsula. Strong influences of animism, Hinduism, traditional Javanese beliefs and Islam are evident in Wayang Kulit Kelantan performances (Ghulam-Sarwar, 1993, pp. 4-5), as well as in the conception of the epic’s characters and their visualization on leather puppets.
Peroxidase extraction from jicama skin peels for phenol removal
Phenol and its derivatives exist in various types of industrial effluents, and are known to be harmful to aquatic lives even at low concentrations. Conventional treatment technologies for phenol removal are challenged with long retention time, high energy consumption and process cost. Enzymatic treatment has emerged as an alternative technology for phenol removal from wastewater. These enzymes interact with aromatic compounds including phenols in the presence of hydrogen peroxide, forming free radicals which polymerize spontaneously to produce insoluble phenolic polymers. This work aims to extract peroxidase from agricultural wastes materials and establish its application for phenol removal. Peroxidase was extracted from jicama skin peels under varying extraction conditions of pH, sample-to-buffer ratio (w/v %) and temperature. Experimental results showed that extraction process conducted at pH 10, 40% w/v and 25oC demonstrated a peroxidase activity of 0.79 U/mL. Elevated temperatures slightly enhanced the peroxidase activities. Jicama peroxidase extracted at optimum extraction conditions demonstrated a phenol removal efficiency of 87.5% at pH 7. Phenol removal efficiency was ∼ 97% in the range of 30 - 40oC, and H2O2 dosage has to be kept below 100 mM for maximum removal under phenol concentration tested
Prostate cancer
The management of prostate cancer continues to evolve rapidly, with substantial advances being made in understanding the genomic landscape and biology underpinning both primary and metastatic prostate cancer. Similarly, the emergence of more sensitive imaging methods has improved diagnostic and staging accuracy and refined surveillance strategies. These advances have introduced personalised therapeutics to clinical practice, with treatments targeting genomic alterations in DNA repair pathways now clinically validated. An important shift in the therapeutic framework for metastatic disease has taken place, with metastatic-directed therapies being evaluated for oligometastatic disease, aggressive management of the primary lesion shown to benefit patients with low-volume metastatic disease, and with several novel androgen pathway inhibitors significantly improving survival when used as a first-line therapy for metastatic disease. Research into the molecular characterisation of localised, recurrent, and progressive disease will undoubtedly have an impact on clinical management. Similarly, emerging research into novel therapeutics, such as targeted radioisotopes and immunotherapy, holds much promise for improving the lives of patients with prostate cancer
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Individual differences in level of wisdom are associated with brain activation during a moral decision-making task.
IntroductionWisdom is reportedly associated with better health and quality of life. However, our knowledge of the neurobiology of wisdom is still in the early stages of development. We aimed to improve our understanding by correlating a psychometric measure of the trait with patterns of brain activation produced by a cognitive task theorized to be relevant to wisdom: moral decision-making. In particular, we aimed to determine whether individual differences in wisdom interact with moral task complexity in relation to brain activation.MethodsParticipants were 39 community-dwelling men and women aged 27-76 years, who completed moral and nonmoral decision-making tasks while undergoing functional magnetic resonance imaging. Brain activation in select regions of interest was correlated with participants' scores on the San Diego Wisdom Scale (SD-WISE).ResultsIndividual differences in wisdom were found to interact with brain response to moral versus nonmoral and moral personal versus impersonal dilemmas, particularly in regions in or near the default mode network. Persons with higher scores on the SD-WISE had less contrast between moral and nonmoral dilemmas and greater contrast between moral-personal and moral-impersonal dilemmas than individuals with lower SD-WISE scores.ConclusionsResults confirmed our hypothesis that individual differences in level of wisdom would interact with moral condition in relation to brain activation, and may underscore the relevance of considering one's own and others' actions and experiences in the context of wise thinking. Future studies are needed to replicate these findings and to examine specific neurocircuits
Symplastic scrotal leiomyoma: a case report
<p>Abstract</p> <p>Introduction</p> <p>Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case.</p> <p>Case presentation</p> <p>We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up.</p> <p>Conclusion</p> <p>Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.</p
What are we downloading for our children? Best-selling children’s apps in four European countries
The present article provides an overview of the best-selling apps for the age range of 0–8 years under various categories, including ‘Kids’, ‘Books’, ‘Educational games’, ‘Family games’ and ‘Word games’ in the two major application stores (Google Play and iTunes App Store) in four economically diverse European countries: Hungary, Turkey, Greece and the Netherlands. As tablets seem to be a substantial part of children’s leisure activities, and thus apps might play an important role in their development, we conducted a content analysis to highlight two issues: the educational value of the most popular children’s apps and the fine-tuning of apps to the local culture and language of non-English speaking countries. There is a large overlap between the best-selling apps in the four countries; in fact, half of the apps appear among the most popular lists in more than one country. Consequently, most children’s apps do not include any oral language and, if they do, they are not available in the local language. Furthermore, the results show that a substantial part of the apps supported early literacy skills. In the majority of apps teaching literacy, although advertised for the youngest, the focus of instruction was more suited for school-age children
Media relations in an evolving media landscape
Purpose
– The purpose of this paper is to test the viability of the media relations framework, Mediating the Media model (Pang, 2010), and ascertains its relevance to practitioners in a changing media landscape in Singapore where social media is emerging as an alternative source of information tool.
Design/methodology/approach
– In-depth interviews with 20 media relations practitioners who were former journalists. Practitioners with journalism experience were chosen as they perform better at media relations (Sallot and Johnson, 2006a; Sinaga and Callison, 2008).
Findings
– The model posits two sets of influences, i.e. internal (journalist mindset, journalist routines and newsroom routines) and external (extra-media forces and media ideology) in media relations. Internal influences were found to be more prevalent than external influences and journalist mindset was the most pervasive factor influencing media relations.
Research limitations/implications
– Findings are based solely on interviews and some claims cannot be corroborated. As this is a qualitative study situated in one country, it is also not generalizable.
Practical implications
– This study will serve useful insights for new practitioners to approach media relations in a holistic and systematic manner and for seasoned practitioners to re-evaluate their current media strategies.
Originality/value
– This inaugural test found rigor in the model, and affords an in-depth understanding of the dynamics of journalist-practitioner relationships in a changing media landscape. It also presents an intriguing opportunity for the model to be applied to countries where the media industry operates under vastly different environments so as to ensure that the model stands up to scrutiny as it seeks to be positioned as a viable model for media relations.
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