The Role of Final State Interactions in Quasielastic 56^{56}Fe(e,e′)(e,e') Reactions at large ∣q⃗∣|\vec q|

A relativistic finite nucleus calculation using a Dirac optical potential is used to investigate the importance of final state interactions [FSI] at large momentum transfers in inclusive quasielastic electronuclear reactions. The optical potential is derived from first-order multiple scattering theory and then is used to calculate the FSI in a nonspectral Green's function doorway approach. At intermediate momentum transfers excellent predictions of the quasielastic $^{56}$Fe$(e,e')$ experimental data for the longitudinal response function are obtained. In comparisons with recent measurements at $|{\vec q|}=1.14$~GeV/c the theoretical calculations of $R_L$ give good agreement for the quasielastic peak shape and amplitude, but place the position of the peak at an energy transfer of about $40$~MeV higher than the data.Comment: 13 pages typeset using revtex 3.0 with 6 postscript figures in accompanying uuencoded file; submitted to Phys. Rev.

Energy Dependence of the NN t-matrix in the Optical Potential for Elastic Nucleon-Nucleus Scattering

The influence of the energy dependence of the free NN t-matrix on the optical potential of nucleon-nucleus elastic scattering is investigated within the context of a full-folding model based on the impulse approximation. The treatment of the pole structure of the NN t-matrix, which has to be taken into account when integrating to negative energies is described in detail. We calculate proton-nucleus elastic scattering observables for $^{16}$O, $^{40}$Ca, and $^{208}$Pb between 65 and 200 MeV laboratory energy and study the effect of the energy dependence of the NN t-matrix. We compare this result with experiment and with calculations where the center-of-mass energy of the NN t-matrix is fixed at half the projectile energy. It is found that around 200 MeV the fixed energy approximation is a very good representation of the full calculation, however deviations occur when going to lower energies (65 MeV).Comment: 11 pages (revtex), 6 postscript figure

Full-Folding Optical Potentials for Elastic Nucleon-Nucleus Scattering based on Realistic Densities

Optical model potentials for elastic nucleon nucleus scattering are calculated for a number of target nuclides from a full-folding integral of two different realistic target density matrices together with full off-shell nucleon-nucleon t-matrices derived from two different Bonn meson exchange models. Elastic proton and neutron scattering observables calculated from these full-folding optical potentials are compared to those obtained from `optimum factorized' approximations in the energy regime between 65 and 400 MeV projectile energy. The optimum factorized form is found to provide a good approximation to elastic scattering observables obtained from the full-folding optical potentials, although the potentials differ somewhat in the structure of their nonlocality.Comment: 21 pages, LaTeX, 17 postscript figure

Conservation and biology of the rediscovered nationally endangered Canterbury knobbled weevil, Hadramphus tuberculatus

Three areas near Burkes Pass Scenic Reserve were surveyed for the presence of Hadramphus tuberculatus, a recently rediscovered endangered weevil. The reserve itself was resurveyed to expand on a 2005/2006 survey. Non-lethal pitfall traps and mark and recapture methods were used. Six H. tuberculatus were caught in pitfall traps over 800 trap nights. Day and night searching of Aciphylla aurea was conducted. Four specimens were observed on Aciphylla flowers between 9 am and 1.30 pm within the reserve. No specimens were found outside of the reserve by either method. Other possible locations where H. tuberculatus may be found were identified and some visited. At most locations Aciphylla had already finished flowering, no H. tuberculatus were found. Presence of H. tuberculatus at other sites would be best determined by searching of Aciphylla flowers during the morning from late October onwards

An Acoustic Technique for the Noninvasive in-Situ Measurement of Crystal Size and Solution Concentration

We demonstrated the use of acoustic measurements for tracking potassium dihydrogen phosphate (KDP) crystal growth. Both KDP solution concentration and KDP crystal size can be found by using information derived from acoustic wave propagation in the solution. Acoustic measurements show good correlation to conductivity measurements for KDP solution concentration

Antitumor activity of an anti-CD98 antibody.

CD98 is expressed on several tissue types and specifically upregulated on fast-cycling cells undergoing clonal expansion. Various solid (e.g., nonsmall cell lung carcinoma) as well as hematological malignancies (e.g., acute myeloid leukemia) overexpress CD98. We have identified a CD98-specific mouse monoclonal antibody that exhibits potent preclinical antitumor activity against established lymphoma tumor xenografts. Additionally, the humanized antibody designated IGN523 demonstrated robust tumor growth inhibition in leukemic cell-line derived xenograft models and was as efficacious as standard of care carboplatin in patient-derived nonsmall lung cancer xenografts. In vitro studies revealed that IGN523 elicited strong ADCC activity, induced lysosomal membrane permeabilization and inhibited essential amino acid transport function, ultimately resulting in caspase-3 and -7-mediated apoptosis of tumor cells. IGN523 is currently being evaluated in a Phase I clinical trial for acute myeloid leukemia (NCT02040506). Furthermore, preclinical data support the therapeutic potential of IGN523 in solid tumors

Ultra-broadband wavelength-swept Tm-doped fiber laser using wavelength-combined gain stages

A wavelength-swept thulium-doped fiber laser system employing two parallel cavities with two different fiber gain stages is reported. The fiber gain stages were tailored to provide emission in complementary bands with external wavelength-dependent feedback cavities sharing a common rotating polygon mirror for wavelength scanning. The wavelength-swept laser outputs from the fiber gain elements were spectrally combined by means of a dichroic mirror and yielded over 500 mW of output with a scanning range from ~1740 nm to ~2070 nm for a scanning frequency of ~340 Hz

Lab-On-Chip Clinorotation System for Live-Cell Microscopy Under Simulated Microgravity

Cells in microgravity are subject to mechanical unloading and changes to the surrounding chemical environment. How these factors jointly influence cellular function is not well understood. We can investigate their role using ground-based analogues to spaceflight, where mechanical unloading is simulated through the time-averaged nullification of gravity. The prevailing method for cellular microgravity simulation is to use fluid-filled containers called clinostats. However, conventional clinostats are not designed for temporally tracking cell response, nor are they able to establish dynamic fluid environments. To address these needs, we developed a Clinorotation Time-lapse Microscopy (CTM) system that accommodates lab-on- chip cell culture devices for visualizing time-dependent alterations to cellular behavior. For the purpose of demonstrating CTM, we present preliminary results showing time-dependent differences in cell area between human mesenchymal stem cells (hMSCs) under modeled microgravity and normal gravity

Wavelength-swept Tm-doped fiber laser operating in the two-micron wavelength band

A wavelength-swept thulium-doped silica fiber laser using an intracavity rotating slotted-disk wavelength scanning filter in combination with an intracavity solid etalon for passive control of temporal and spectral profiles is reported. The laser yielded a wavelength swept output in a step-wise fashion with each laser pulse separated from the previous pulse by a frequency interval equal to the free-spectral-range of the etalon and with an instantaneous linewidth of <0.05 nm. Scanning ranges from 1905 nm to 2049 nm for a cladding-pumping laser configuration, and from 1768 nm to 1956 nm for a core-pumping laser configuration were achieved at average output powers up to ~1 W

Inclusive quasi-elastic electron-nucleus scattering

This article presents a review of the field of inclusive quasi-elastic electron-nucleus scattering. It discusses the approach used to measure the data and includes a compilation of data available in numerical form. The theoretical approaches used to interpret the data are presented. A number of results obtained from the comparison between experiment and calculation are then reviewed. The analogies and differences to other fields of physics exploiting quasi-elastic scattering from composite systems are pointed out.Comment: Accepted for publication in Reviews of Modern Physic