2,899 research outputs found
Concanavalin A-Binding Enzymes of Crotalus scutulatus scutulatus Venom
Crotalus scutulatus scutulatus crude venom was separated into two fractions by Concanavalin A Sepharose 4B affinity chromatography. The proteins binding to Con A exhibited phosphomonoesterase (orthophosphoric monoester phosphohydrolase EC 3.1.3.2), phosphodiesterase, 5\u27-nucleotidase (5\u27-ribonucleotide phosphohydrolase EC 3.1.3.5), phospholipase A(phosphatidate 2-acylhydrolase EC 3.1.1 .4), hyaluronidase (hyaluronate glycanohydrolase EC 3.2.1 d), N-benzoyl-L-arginine ethyl esterase, p-toluenesulfonyl-L-arginine methyl esterase, L-amino acid oxidase (L-amino acid: 02 oxidoreductase [deaminating] EC 1.4.3.2), and caseinolytic activities. Thrombin-like and NAD nucleosidase (5\u27-ribonucleotide phosphohydrolase EC 3.1.3.5) activities were not observed. The crude venom and the fraction containing the glycoproteins which bound to Con A were fractionated by DEAE Sephadex A-50 ion exchange chromatography. Each of these samples yielded fractions having caseinolytic activities
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Strength of the DTM RapidSteel 1.0 Material
This paper reports the results of a study into the strength of the DTM RapidSteel 1.0 material.
Elastic modulus and strength of the metal/copper composite material was investigated as a
function of the distance from the point of copper infiltration, the furnace cycle duration, and the
furnace type. The microstructure of the RapidSteel material was also examined in an attempt to
understand the science behind the infiltration process. The results have implications for the
design of tools to be made using the RapidTool process in situations where the tool will be used
as a production tool, rather than a prototype tool.Mechanical Engineerin
Concanavalin A-Nonbinding Enzymes of Crotalus scutulatus scutulatus Venom
Crotalus scutulatus scutulatus crude venom was separated into two fractions by Concanavalin A Sepharose 4B affinity chromatography. The Concanavalin A-nonbinding fraction (F-l) exhibited phosphomonoesterase (orthophosphoric monoester phosphohydrolase EC 3.1 .3.2), phosphodiesterase, 5 \u27-nucleotidase (5 \u27-ribonucleotide phosphohydrolase EC 3.1.3.5), phospholipase A (phosphatidate 2-acylhydrolase EC 3.1.1.4), hyaluronidase (hyaluronate glycanohydrolase EC 3.2.1.d), N-benzoyl-Larginine ethyl esterase, p-toluenesulfonyl-L-arginine methyl esterase, L-amino acid oxidase (L-amino acid: O2 oxidoreductase [deaminating] EC 1.4.3.2), and caseinolytic activities. Thrombin-like and NAD nucleosidase (5 \u27-ribonudeotide phosphohydrolase EC 3.1.3.5) activities were not observed. DEAE Sephadex A-50 ion exchange chromatography by two stage elution of F-l yielded several fractions having proteinase activities. Proteinase activity was observed in the latter fractions of the first elution and in the fractions of the second elution
Architectures for a quantum random access memory
A random access memory, or RAM, is a device that, when interrogated, returns
the content of a memory location in a memory array. A quantum RAM, or qRAM,
allows one to access superpositions of memory sites, which may contain either
quantum or classical information. RAMs and qRAMs with n-bit addresses can
access 2^n memory sites. Any design for a RAM or qRAM then requires O(2^n)
two-bit logic gates. At first sight this requirement might seem to make large
scale quantum versions of such devices impractical, due to the difficulty of
constructing and operating coherent devices with large numbers of quantum logic
gates. Here we analyze two different RAM architectures (the conventional fanout
and the "bucket brigade") and propose some proof-of-principle implementations
which show that in principle only O(n) two-qubit physical interactions need
take place during each qRAM call. That is, although a qRAM needs O(2^n) quantum
logic gates, only O(n) need to be activated during a memory call. The resulting
decrease in resources could give rise to the construction of large qRAMs that
could operate without the need for extensive quantum error correction.Comment: 10 pages, 7 figures. Updated version includes the answers to the
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A Quantum Random Walk Search Algorithm
Quantum random walks on graphs have been shown to display many interesting
properties, including exponentially fast hitting times when compared with their
classical counterparts. However, it is still unclear how to use these novel
properties to gain an algorithmic speed-up over classical algorithms. In this
paper, we present a quantum search algorithm based on the quantum random walk
architecture that provides such a speed-up. It will be shown that this
algorithm performs an oracle search on a database of items with
calls to the oracle, yielding a speed-up similar to other quantum
search algorithms. It appears that the quantum random walk formulation has
considerable flexibility, presenting interesting opportunities for development
of other, possibly novel quantum algorithms.Comment: 13 pages, 3 figure
Regional pressure and temperature differences across the injured human brain : comparisons between intraparenchymal and ventricular measurements
Introduction: Intraparenchymal, multimodality sensors are commonly used in the management of patients with severe traumatic brain injury (TBI). The ‘gold standard’, based on accuracy, reliability and cost for intracranial pressure (ICP) monitoring is within the cerebral ventricle (external strain gauge). There are no standards yet for intracerebral temperature monitoring and little is known of temperature differences between brain tissue and ventricle. The aim of the study therefore was to determine pressure and temperature differences at intraparenchymal and ventricular sites during five days of continuous neurominitoring.
Methods: Patients with severe TBI requiring emergency surgery. Inclusion criteria: patients who required ICP monitoring were eligible for recruitment. Two intracerebral probe types were used: a) intraventricular, dual parameter sensor (measuring pressure, temperature) with inbuilt catheter for CSF drainage: b) multiparameter intraparenchymal sensor measuring pressure, temperature and oxygen partial pressure. All sensors were inserted during surgery and under aseptic conditions.
Results: Seventeen patients, 12 undergoing neurosurgery (decompressive craniectomy n=8, craniotomy n=4) aged 21–78 years were studied. Agreement of measures for 9540 brain tissue-ventricular temperature ‘pairs’ and 10,291 brain tissue-ventricular pressure ‘pairs’ were determined using mixed model to compare mean temperature and pressure for longitudinal data. There was no significant overall difference for mean temperature (p=0.92) or mean pressure readings (p=0.379) between tissue and ventricular sites. With 95.8% of paired temperature readings within 2SD (−0.4 to 0.4°C) differences in temperature between brain tissue and ventricle were clinically insignificant. For pressure, 93.5% of readings pairs fell within the 2SD range (−9.4756 to 7.8112 mmHg) (Fig. 2). However, for individual patients, agreement for mean tissue-ventricular pressure differences was poor on occasions.
Conclusions: There is good overall agreement between paired temperature measurements obtained from deep white matter and brain ventricle in patients with and without early neurosurgery. For paired ICP measurements, 93.5% of readings were within 2SD of mean difference. Whilst the majority of paired readings were comparable (within 10mmHg) clinically relevant tissue-ventricular dissociations were noted. Further work is required to unravel the events responsible for short intervals of pressure dissociation before tissue pressure readings can be definitively accepted as a reliable surrogate for ventricular pressure.</p
Optimal discrimination of quantum operations
We address the problem of discriminating with minimal error probability two
given quantum operations. We show that the use of entangled input states
generally improves the discrimination. For Pauli channels we provide a complete
comparison of the optimal strategies where either entangled or unentangled
input states are used.Comment: 4 pages, no figure
Dynamics of entropy and nonclassical properties of the state of a -type three-level atom interacting with a single-mode cavity field with intensity-dependent coupling in a Kerr medium
In this paper, we study the interaction between a three-level atom and a
quantized single-mode field with intensity-dependent coupling in a Kerr medium.
The three-level atom is considered to be in a -type configuration.
Under particular initial conditions, which may be prepared for the atom and
the field, the dynamical state vector of the entire system will be explicitly
obtained, for arbitrary nonlinearity function associated to any physical
system.
Then, after evaluating the variation of the field entropy against time, we
will investigate the quantum statistics as well as some of the nonclassical
properties of the introduced state. During our calculations we investigate the
effects of intensity-dependent coupling, Kerr medium and detuning parameters on
the depth and domain of the nonclassicality features of the atom-field state
vector. Finally, we compare our obtained results with those of -type
three-level atoms.Comment: 18 pages, 7 Figure
Theory versus experiment for the rotordynamic coefficients of annular gas seals. Part 1: Test facility and apparatus
A facility and apparatus are described for determining the rotordynamic coefficients and leakage characteristics of annular gas seals. The apparatus has a current top speed of 8000 cpm with a nominal seal diameter of 15.24 cmn (6 in). The air supply unit yields a seal pressure ratio of approximately 7. An external shaker is used to excite the test rotor. The capability to independently calculate all rotordynamic coefficients at a given operating condition with one excitation frequency are discussed
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