Analysis of static behavior of a P-FGM Beam

In this paper, the systematic arrangements are acquired to foresee the static behavior of the P-FGM beam and which have been gotten by Navier's solution. The numerical outcomes got by the new shear models are presented and compared with those available in the literature to see the influence of the geometry and the mixing law on the static behavior of this type of FGM beams

Ultraregular generalized functions

Algebras of ultradifferentiable generalized functions are introduced. We give a microlocal analysis within these algebras related to the regularity type and the ultradifferentiable property.Comment: This paper is the composition of our two recent paper

Investigations in static response and free vibration of a functionally graded beam resting on elastic foundations

In this article, an analytical study was done to predict the behavior of the beam vis-à-vis bending, buckling, and dynamic responses of isotropic homogeneous beams based on an elastic foundation. The material properties of the FG-beams vary across the thickness using the power law. In this work, the sinusoidal shear deformation beams theory is used to investigate the static and dynamic behavior of FG beams. The present theory fulfills the condition of nullity of edge stresses and does not require the use of a shear correction factor. Hamilton's principle is used to deduce equations of motion, and analytical solutions for simply supported beams were obtained using the Navier resolution method. Nondimensional displacements, eigenfrequencies and critical-buckling loadcs of isotropic homogeneous beams were obtained for various values of the foundation parameters. The numerical results obtained by the present technique have been compared with the results of literature and are in excellent agreement with them. It can be concluded that the current HSDBT is simple and accurate in solving the bending, eigenfrequency and critical-buckling load problems for FGM beams

Des «nanotransporteurs» d’ADN : Repousser les limites des Nanomédicaments pour traiter le cancer

AbstractUne nouvelle classe de transporteurs de médicaments fabriqués avec de l’ADN,qui pourrait améliorer de façon importante le traitement des cancers et d’autresmaladies, a été conçue et validée par une équipe de chercheur de l’université deMontréal. Contrairement aux nano-véhicules artificiels actuels (liposomes…), où laconcentration de médicament libéré dans le temps par ces véhicules peut variergrandement d’un patient à l’autre, ces transporteurs moléculaires d’ADN peuventêtre programmés pour délivrer et maintenir une dose thérapeutique optimale demédicaments dans le sang tout au long du traitement, ce qui les rend plus efficaceset plus précis.Les tests effectués sur des cellules et des modèles animaux se révèlent prometteurspour deux applications de ces nanotransporteurs d’ADN : l’une contenant la Quinine,un antipaludéen, et l’autre contenant la Doxorubicine, un antibiotique cytotoxiqueanthracyclinique couramment employé pour traiter le cancer du sein et la leucémie

Methodology of mechanical characterization of coated spherical materials

The aim of this work was to develop a methodology for the mechanical characterization of catalyst beads with a core-shell structure and more especially for coated spherical granules. Supports composed of an alpha alumina core coated by gamma alumina shell were shaped by pan coating to this purpose. The proposed methodology started with the characterization of the microstructure of the coating and the highlight of potential macro defects within. Thereafter three tests simulating mechanical stress, such as impact, compression (bulk crushing test), and shear (drum attrition test) are used. The operational parameters of these tests were also optimised in order to stress preferentially the shell of the coated materials. Among the evaluated tests, drum attrition seems to be most efficient for characterizing coated spherical granules