Assessment of Physical Growth in Male Children Infected with Human Immunodeficiency Virus on Highly Active Antiretroviral Therapy in Abakaliki

Background: Human immunodeficiency virus (HIV) infection causes a derangement in growth. Antiretrovirals promote immune function restoration and improvement in the quality of life. Variables such as poor adherence to drugs and unsuppressed viral load may negatively influence growth in HIV-infected children. The study aimed at determining the growth in HIV-infected males aged 8–17 years in Abakaliki who were on antiretrovirals. Methods: Acase–control hospital-based study, involving 80 HIV-infected males aged 8–17 years who were matched for age and socioeconomic class with 80 HIV‑uninfected controls. Growth parameters including the heights, weights, and body mass index (BMI) of subjects and controls were measured, and Z scores for age derived for height, weight, and BMI. Results: The mean height of subjects (1.420 ± 0.18 m) was significantly lower than that of controls (1.515 ± 0.17 m). The mean weight of subjects (35.09 ± 12.48 kg) was significantly low compared to controls (42.21 ± 12.95 kg). A significant difference was documented in the mean BMI for age among subjects (16.78 ± 2.12 kg/m2 ) and controls (17.93 ± 2.27 kg/m2 ). There was a significant relationship between CD4 count and growth (BMI) (P = 0.006) and between duration on highly active antiretroviral therapy and growth (P = 0.024). Conclusion: HIV‑infected males had significantly impaired growth despite the use of antiretroviral drugs. Keywords: Children, human immunodeficiency virus antiretroviral drugs, males, physical growt

Determinants of Audit Quality in the Nigerian Business Environment

The objective of this study was to analyze the determinants of audit quality in the Nigerian business environment. The research empirically examined the relationship between audit quality, engagement and firm related characteristics such as audit tenure, audit firm size, board independence and ownership structure. A regression model was used to analyze the existence of significant relationships between audit quality and the firm/audit related characteristics. Audit firm size, board independence and ownership structure were found to be positively related to audit quality; however, only board independence exhibited a significant relationship with audit quality. Audit tenure exhibited a negative relationship with audit quality which was also not significant. The study recommends the sustenance and possible improvements on the non-executive board composition of organizations. Keywords: Audit Quality, Audit Tenure, Audit Firm Size, Board Independence, Ownership Structure

Growth performance and carcass characteristics of F1 progenies of local x exotic chicken crosses

Growth performance and carcass characteristics of F1 progenies of local hen (Black and Brown normal feathered) and exotic male (Ross 308 and Arbor Acre) strains were evaluated. Base population had 60 dams, 30 each of Brown and Black phenotype and 24 exotic sires, 12 each of Arbor Acre and Ross 308. The experiment had 4 genetic groups – Ross 308 sire x Brown dam (A1R1), Ross 308 x Black dam (A1R2), Arbor Acre sire x Brown dam (A2R1) and Arbor Acre sire x Black dam (A2R2). Growth performance traits measured were final body weight, daily feed intake, average daily weight gain (ADWG), FCR and mortality. Body weight (BW) and linear body traits (LBM) – thigh length (TL), shank length (SL), breast width (BWDT), body length (BL), wing length (WL), keel length (KL), drumstick (DS) were measured as well as carcass and organ traits. Results of growth performance traits showed significantly (P<0.05) higher final BW, ADWG and better FCR in A1R1 progenies. Significant (P<0.05) differences were observed among the four strains for BWDT, DS, BW. KL. SL and WL. It was also observed that F1 progenies of A1R1 recorded significantly (P<0.05) longer TL, SL, KL, WL, and BL and weighed heavier. Carcass and organ traits showed significant (P<0.05) differences among the genotypes. F1 progenies of A1R1 were significantly (P<0.05) different from the other genotypes. It was concluded that genetic variation exists among the progenies for the traits and that Ross 308 x Brown local dams is best suited for improving the local stock in the study area

Design topology of a remote-controlled bi-directional rotation of an A.C. fan with speed control

The use of remote control for alternating current fans in homes/offices is one of the applications of electronics that enhances human comfort. It should therefore not be seen as luxury, rather, it should be taken as a basic requirement of life. In this study, the bi-directional rotation and speed control of ac fan were achieved using ardiuno microcontroller and tuned capacitors circuit. The use of the new state-of- the art technique in this work is significant because it helped in over-coming the drawbacks associated with the use of inductive, resistive and phase angle controlled regulators. The significance of this study will be of great benefit to physically challenged and aged persons who need to have their comforts in their various places of sitting. The designed topology of the work was executed and achieved. Reliability test carried out on the finished work showed better efficiency

Impacts of a Pilot of Community Antiretroviral Group Initiative on HIV‑Positive Patients in a Tertiary Health Facility in Abuja, North Central Nigeria

Background: Decentralization, as seen in community antiretroviral group (CAG), has resulted in a significant decline in deaths from AIDS‑related causes with projected further benefits in middle‑ and low‑income countries, such as Nigeria. After 2 years of CAG implementation in our facility, this study is designed to assess its impacts on the pilot‑cohort of patients, (individual and group), and the hospital facility. Materials and Methods: Pooled data from the CAG register of the pilot cohort of 84 clients, was used for the study. Review of data at entry and 2 years after was done. A questionnaire was used to obtain additional qualitative data. This was administered to all the eighty‑four pilot patients and 31 caregivers. Results: There were eight locations, with 84, clients, 62 females and 22 males. The mean/standard deviation of age was 39.38 ± 9.68 years. There were significant increases in weight (kg), (from 65.94 ± 11.012 to 70.69 ± 11.465, P < 0.001), body mass index (kg/m2), (from 24.77 ± 3.879 to 26.79 ± 4.282 P < 0.001), packed cell volume (%) from (31.19 ± 5.014 to 35.64 ± 5.131, P < 0.001), CD4 (cells/mm3), (from 394.36 ± 193.094 to 563.87 ± 220.137 P < 0.001). The viral load suppression was sustained, reducing even further, from 85.06 ± 182.329 to 31.10 ± 46.648 copies/ml, P < 0.001. Retention in care and outcomes were better. Conclusions: From this pilot, the CAG model has shown promise in reducing attrition, improving quality of care, and other direct and indirect  benefits, including; cardiovascular, nutritional, and socioeconomic. This has justified the scale‑up of this laudable model that will further improve the quality of care given to the patients and the overall quality profile of the facility and system. Keywords: Abuja, antiretroviral‑care, decentralization, pilo

The prevalence and determinants of female serodiscordance among HIV positive pregnant women attending PMTCT clinic in Owerri, Imo state, Nigeria

Background: Human Immunodeficiency Virus sero-discordance is high among heterosexual couples in Africa. However, only few studies have explored the factors that are associated with the prevalence in sub-Saharan Africa. The aim of this study was to determine the prevalence of female sero-discordance among HIV positive pregnant women in Owerri and to assess its possible associated factors.Methods: A cross sectional study of pregnant women (and their partners) who tested positive to HIV I and II at the Prevention of Mother to Child Transmission (PMTCT) clinic from December 2015 to May 2016 in Federal Medical Center Owerri, Imo state, Nigeria.Results: A total of 106 HIV positive pregnant women (and their partners) were studied. The prevalence of female serodiscordance was 63.2% (67/106). Pre-marital serodiscordance contributed about 52.2% (35/67) female serodiscordance among couples in the study. Sero-discordance rate for the lower, middle, and upper classes were 50% (28/56), 76.1% (35/46) and 100% (4/4) respectively and was statistically significant (p<0.01). Condom use was significantly associated with female serodiscondance (P<0.01). CD4+ count of the female partner at booking was also found statistically significantly associated with female serodiscordance (P<0.01).Conclusions: There is high prevalence of female serodiscordance among HIV positive pregnant women in Owerri. Pre-marital serodiscordance contributed significantly to high level of female serodiscordance among couples. Higher social class, condom use and high female- partner CD4+ count are significantly associated with female sero-discordance

Trial of Labour after Caesarean Section in a Secondary Health Facility in Abakaliki, Nigeria

Background: The mode of delivery of a parturient is influenced by previous caesarean section (CS) scar. Objective: The objective of the study is to evaluate the pregnancy outcomes of a parturient with one previous caesarean delivery that was managed in Mile Four hospital, Abakaliki, Nigeria. Materials and Methods: A 5‑year retrospective study of women with one previous CS who delivered in Mile Four hospital between January 2011 and December 2015 was done. IBM SPSS version 20 was used for data analysis, and data were represented using frequency tables, charts, and Chi‑square. The level of significance was set at an alpha level of 0.05. Results: Three hundred and twenty‑two (322) women with one previous CS were selected for a trial of labor after A C/S (TOLAC). More than half of the women (53.1%) had successful TOLAC while 46.9% had a repeat CS. Of the 53.1% of women who had a successful TOLAC, One hundred and forty-one patients had spontaneous vertex delivery. Seventeen women (9.9%) on the TOLAC arm had a ruptured uterus, while seven patients (4.6%) failed the TOLAC group had uterine dehiscence. Haemorrhage was the most common maternal complication. Severe asphyxia and perinatal death were present in 5.9% and 5.3% of neonates on TOLAC arm, respectively. Conclusion: Trial of labour after a CS can result in an excellent outcome in a well‑selected patient. The success rate of 53.1% in our study is encouraging. However, adequate intrapartum monitoring is recommended to reduce maternal and fetal complications

Assessment of age at menarche and menstrual pattern among secondary school girls in Awka, Southeast Nigeria

Background: Menarche is an important physiological milestone in girls and this usually occurs during their secondary school years. The menstrual pattern may vary in these adolescents. This knowledge may assist in counselling the young girls on reproductive health issues.Methods: A cross-sectional study of female secondary school students from Kenneth Dike secondary school, Awka; Amaenyi girls’ secondary school and community secondary school, Okpuno, all in Awka, Anambra state of Nigeria. All together 545 students were selected following informed consent. The study instrument was a pre-tested, semi-structured and self-administered questionnaire. Data analysis was done with IBM SPSS 20 software. Tests of association between variables were done with Fisher’s exact test and the level of significance set at p≤0.05. Results: The mean age of the 545 respondents was 16.79±1.736 years and majority of them are of the Igbo ethnic group (90.5%). The average age at menarche was 12.77±1.159 years. There is a significant difference between the age at menarche and the father’s occupation. The modal duration of flow was 4 days (48.7%) while 95.2% had a normal cycle length of 21-35 days.Conclusions: The average age of menarche of secondary school girls in Awka was 12.77±1.159 years. Most of the students had normal menstrual flow duration of 2-7 days with a cycle length of 21-35 days

Desire to practice postpartum contraception among antenatal women at Awka, Southeast Nigeria

Background: Postpartum contraception enables the nursing woman recover from the effects of pregnancy and childbirth before embarking on another pregnancy. It also promotes child welfare. The assessment of the desire by pregnant women to take up postpartum contraceptive service will help the planning of good delivery of this service.Methods: A cross-sectional study of antenatal clinic attendees at Chukwuemeka Odumegwu Ojukwu Teaching Hospital, Awka was done using a pretested interviewer-administered questionnaire. Data was analyzed with IBM SPSS version 20 software and associations between variables were tested with Chi square. Level of significance was set at P ≤0.05.Results: A total of 262 antenatal women were interviewed. The mean age of the respondents was 29.1±6.1 years while the mean parity was 2.5±1.5. Two hundred and one of the study women (76.7%) had the desire to practice postpartum contraception after the index pregnancy while only 9 (3.4%) were unsure whether they had the desire or not. Multiparous women are more likely to desire postpartum contraception (P <0.01). Also, previous use of contraception (P<0.01), desired index pregnancy (P=0.01) and being married or single (P=0.02) are all significantly associated with the desire to practice postpartum contraception.Conclusions: There was a high level of desire to practice postpartum contraception among antenatal clinic attendees at Awka. Parity, marital status, desired index pregnancy and previous practice of contraception all influence this desire

Exploring genetic variability, heritability, and trait correlations in gari and eba quality from diverse cassava varieties in Nigeria.

Open Access ArticleBACKGROUND Gari (especially in Nigeria) is an important West African food product made from cassava. It is an affordable, precooked, dry, easy to prepare and store food product. Eba is a stiff dough produced by reconstituting gari in hot water. Gari and eba quality is an important driver of varietal acceptance by farmers, processors, and consumers. RESULTS This study characterized the genetic variability, heritability, and correlations among quality-related traits of fresh roots, gari, and eba. Thirty-three diverse genotypes, including landraces and released and advanced breeding genotypes, were used in this study. In total, 40 traits categorized into fresh root quality, colour, functional, and texture properties trait groups were assessed. We observed broad phenotypic variability among the genotypes used in this study. Dry matter content had a positive (P < 0.05) correlation with gari%, bulk density and a negative correlation with eba hardness and gumminess. Broad-sense heritability across all environments varied considerably among the different trait groups: 62% to 79% for fresh root quality, 0% to 96% for colour, 0% to 79% for functional and 0% to 57% for texture properties. CONCLUSIONS The stable broad-sense heritability found for gari%, gari and eba colour, bulk density, swelling index, and hardness measured using instrumental texture profile analysis coupled with sufficient variability in the population indicate good potential for genetic improvement of these traits through recurrent selection. Also, it is possible to genetically improve gari%, bulk density, and swelling power by simultaneously improving the dry matter content of fresh roots