6,270 research outputs found
LM radar reflectivity simulation Final report
Ultrasonic simulation of lunar module radar reflectivit
Storm‐time configuration of the inner magnetosphere: Lyon‐Fedder‐Mobarry MHD code, Tsyganenko model, and GOES observations
[1] We compare global magnetohydrodynamic (MHD) simulation results with an empirical model and observations to understand the magnetic field configuration and plasma distribution in the inner magnetosphere, especially during geomagnetic storms. The physics-based Lyon-Fedder-Mobarry (LFM) code simulates Earth\u27s magnetospheric topology and dynamics by solving the equations of ideal MHD. Quantitative comparisons of simulated events with observations reveal strengths and possible limitations and suggest ways to improve the LFM code. Here we present a case study that compares the LFM code to both a semiempirical magnetic field model and to geosynchronous measurements from GOES satellites. During a magnetic cloud event, the simulation and model predictions compare well qualitatively with observations, except during storm main phase. Quantitative statistical studies of the MHD simulation shows that MHD field lines are consistently under-stretched, especially during storm time (Dst \u3c −20 nT) on the nightside, a likely consequence of an insufficient representation of the inner magnetosphere current systems in ideal MHD. We discuss two approaches for improving the LFM result: increasing the simulation spatial resolution and coupling LFM with a ring current model based on drift physics (i.e., the Rice Convection Model (RCM)). We show that a higher spatial resolution LFM code better predicts geosynchronous magnetic fields (not only the average Bz component but also higher-frequency fluctuations driven by the solar wind). An early version of the LFM/RCM coupled code, which runs so far only for idealized events, yields a much-improved ring current, quantifiable by decreased field strengths at all local times compared to the LFM-only code
Probing the superconducting gap symmetry of PrRuSb: A comparison with PrOsSb
We report measurements of the magnetic penetration depth in single
crystals of PrRuSb down to 0.1 K. Both and superfluid
density exhibit an exponential behavior for 0.5, with
parameters (0)/\textit{k}\textit{T} = 1.9 and
= 2900 \AA. The value of (0) is consistent with the specific-heat jump
value of = 1.87 measured elsewhere, while the value of
is consistent with the measured value of the electronic
heat-capacity coefficient . Our data are consistent with
PrRuSb being a moderate-coupling, fully-gapped superconductor. We
suggest experiments to study how the nature of the superconducting state
evolves with increasing Ru substitution for Os
Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia
BACKGROUND: Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks and associated biological processes regulated by FoxO during cancer cachexia are unknown. We hypothesize that FoxO is a central upstream regulator of diverse gene networks in skeletal muscle during cancer that may act coordinately to promote the wasting phenotype. METHODS: To inhibit endogenous FoxO DNA-binding, we transduced limb and diaphragm muscles of mice with AAV9 containing the cDNA for a dominant negative (d.n.) FoxO protein (or GFP control). The d.n.FoxO construct consists of only the FoxO3a DNA-binding domain that is highly homologous to that of FoxO1 and FoxO4, and which outcompetes and blocks endogenous FoxO DNA binding. Mice were subsequently inoculated with Colon-26 (C26) cells and muscles harvested 26 days later. RESULTS: Blocking FoxO prevented C26-induced muscle fiber atrophy of both locomotor muscles and the diaphragm and significantly spared force deficits. This sparing of muscle size and function was associated with the differential regulation of 543 transcripts (out of 2,093) which changed in response to C26. Bioinformatics analysis of upregulated gene transcripts that required FoxO revealed enrichment of the proteasome, AP-1 and IL-6 pathways, and included several atrophy-related transcription factors, including Stat3, Fos, and Cebpb. FoxO was also necessary for the cancer-induced downregulation of several gene transcripts that were enriched for extracellular matrix and sarcomere protein-encoding genes. We validated these findings in limb muscles and the diaphragm through qRT-PCR, and further demonstrate that FoxO1 and/or FoxO3a are sufficient to increase Stat3, Fos, Cebpb, and the C/EBPβ target gene, Ubr2. Analysis of the Cebpb proximal promoter revealed two bona fide FoxO binding elements, which we further establish are necessary for Cebpb promoter activation in response to IL-6, a predominant cytokine in the C26 cancer model. CONCLUSIONS: These findings provide new evidence that FoxO-dependent transcription is a central node controlling diverse gene networks in skeletal muscle during cancer cachexia, and identifies novel candidate genes and networks for further investigation as causative factors in cancer-induced wasting.R01 AR060217 - NIAMS NIH HHS; R01 AR060209 - NIAMS NIH HHS; T32 HD043730 - NICHD NIH HHS; R00 HL098453 - NHLBI NIH HHS; R00HL098453 - NHLBI NIH HHS; R01AR060209 - NIAMS NIH HHS; R01AR060217 - NIAMS NIH HH
Investigating On-Orbit Attitude Determination Anomalies for the Solar Dynamics Observatory Mission
The Solar Dynamics Observatory (SDO) was launched on February 11, 2010 from Kennedy Space Center on an Atlas V launch vehicle into a geosynchronous transfer orbit. SDO carries a suite of three scientific instruments, whose observations are intended to promote a more complete understanding of the Sun and its effects on the Earth's environment. After a successful launch, separation, and initial Sun acquisition, the launch and flight operations teams dove into a commissioning campaign that included, among other things, checkout and calibration of the fine attitude sensors and checkout of the Kalman filter (KF) and the spacecraft s inertial pointing and science control modes. In addition, initial calibration of the science instruments was also accomplished. During that process of KF and controller checkout, several interesting observations were noticed and investigated. The SDO fine attitude sensors consist of one Adcole Digital Sun Sensor (DSS), two Galileo Avionica (GA) quaternion-output Star Trackers (STs), and three Kearfott Two-Axis Rate Assemblies (hereafter called inertial reference units, or IRUs). Initial checkout of the fine attitude sensors indicated that all sensors appeared to be functioning properly. Initial calibration maneuvers were planned and executed to update scale factors, drift rate biases, and alignments of the IRUs. After updating the IRU parameters, the KF was initialized and quickly reached convergence. Over the next few hours, it became apparent that there was an oscillation in the sensor residuals and the KF estimation of the IRU bias. A concentrated investigation ensued to determine the cause of the oscillations, their effect on mission requirements, and how to mitigate them. The ensuing analysis determined that the oscillations seen were, in fact, due to an oscillation in the IRU biases. The low frequencies of the oscillations passed through the KF, were well within the controller bandwidth, and therefore the spacecraft was actually following the oscillating biases, resulting in movement of the spacecraft on the order of plus or minus 20 arcsec. Though this level of error met the ACS attitude knowledge requirement of [35, 70, 70] arcsec, 3 sigma, the desire of the ACS and instrument teams was to remove as much of the oscillation as possible. The Kearfott IRUs have an internal temperature controller, designed to maintain the IRU temperature at a constant temperature of approximately 70 C, thus minimizing the change in the bias drift and scale factors of the mechanical gyros. During ground testing of the observatory, it was discovered that the 83-Hz control cycle of the IRU heaters put a tremendous amount of stress on the spacecraft battery. Analysis by the power systems team indicated that the constant charge/discharge on the battery due to the IRU thermal control cycle could potentially limit the life of the battery. After much analysis, the decision was made not to run the internal IRU heaters. Analysis of on orbit data revealed that the oscillations in the IRU bias had a connection to the temperature of the IRU; changes in IRU temperature resulted in changes in the amplitude and period of the IRU biases. Several mitigating solutions were investigated, the result of which was to tune the KF with larger IRU noise assumptions which allows the KF to follow and correct for the time-varying IRU biases
Optically Thin Metallic Films for High-radiative-efficiency Plasmonics
Plasmonics enables deep-subwavelength concentration of light and has become
important for fundamental studies as well as real-life applications. Two major
existing platforms of plasmonics are metallic nanoparticles and metallic films.
Metallic nanoparticles allow efficient coupling to far field radiation, yet
their synthesis typically leads to poor material quality. Metallic films offer
substantially higher quality materials, but their coupling to radiation is
typically jeopardized due to the large momentum mismatch with free space. Here,
we propose and theoretically investigate optically thin metallic films as an
ideal platform for high-radiative-efficiency plasmonics. For far-field
scattering, adding a thin high-quality metallic substrate enables a higher
quality factor while maintaining the localization and tunability that the
nanoparticle provides. For near-field spontaneous emission, a thin metallic
substrate, of high quality or not, greatly improves the field overlap between
the emitter environment and propagating surface plasmons, enabling high-Purcell
(total enhancement > ), high-quantum-yield (> 50 %) spontaneous emission,
even as the gap size vanishes (35 nm). The enhancement has almost
spatially independent efficiency and does not suffer from quenching effects
that commonly exist in previous structures.Comment: Supporting Information not included but freely available from
DOI:10.1021/acs.nanolett.6b0085
Experimental procedures for precision measurements of the Casimir force with an Atomic Force Microscope
Experimental methods and procedures required for precision measurements of
the Casimir force are presented. In particular, the best practices for
obtaining stable cantilevers, calibration of the cantilever, correction of
thermal and mechanical drift, measuring the contact separation, sphere radius
and the roughness are discussed.Comment: 14 pages, 7 figure
Intrinsic dielectric and spectroscopic behavior of perovskite Ba(Ni1/3Nb2/3)O3–Ba(Zn1/3Nb2/3)O3 microwave dielectric ceramics
[[abstract]]Ceramics of 0.35Ba(Ni1/3Nb2/3)O3–0.65Ba(Zn1/3Nb2/3)O3 were prepared by the mixed oxide route. The effect of the cooling rate (2 °C–240 °C/h) after sintering on the microwave dielectric properties of the ceramics was examined. While the extrinsic factors, such as porosity and secondary phases, markedly influence the dielectric properties in the low-frequency regime, they have minimal effect on these properties in the high-frequency regime. The mechanisms involved in modifying the high-frequency dielectric properties of the materials were investigated by Fourier transform infrared and Raman spectroscopy, in conjunction with the Rietveld analysis of x-ray diffraction (XRD) spectra. A reduction in the cooling rate after sintering results in an increase in the high-frequency Q×f (product of dielectric Q value and measurement frequency) from 42 to 58 THz in the high-frequency regime (∼1.5 THz). Such behavior correlates very well with the increase in the B-site occupancy by Nb (deduced from the Rietveld analyses of XRD spectra) and the increase in the coherency of the lattice vibration (deduced from the reduction in the full-width-at-half-maximum of the A1g(O) Raman mode). In contrast, the cooling rate after sintering has very limited effect on the relative permittivity (varying from 40.8 to 41.9 at 1.5 THz), which is in accord with the phenomenon that the cell volume and the Raman shift of A1g(O) Raman mode are essentially independent of the cooling rate.[[booktype]]紙
Modelling growth of swietenia macrophylla (mahogany) plantation in Gum-Gum Forest Reserve, Sabah.
Growth models can contribute to the forest management decision making process by providing stand development forecasts. Mahogany plantation in Gum-Gum Forest Reserve Sabah was planted in 1968 with spacing 2.74×2.74 m within an area of 0.52 hectare. Diameter at breast height (dbh) and tree height data were collected from year 1969 to 2006. This study aimed to determine the efficient regression equations for growth prediction of the mahogany plantation. Regression models were developed by search from literature as a basis references. Four diameter prediction models and six height prediction models were developed. Proc Reg in SAS was used to evaluate the regression equations. Performance of the model was measured by using root mean square error (RMSE), bias and coefficient of determination (R2). The chosen diameter prediction model is lnH=3.07-10.42D-1+0.1lnA with RMSE (0.31), bias (1.76) and R2 (0.68). The recommended prediction model slightly underestimated the actual diameter. The chosen height prediction model is lnD=354-3.98A-1 with RMSE (0.11), bias (0.01) and R2 (0.91). This recommended height prediction model gives very close height estimate to the actual height
Avaliação da incidência de Murcha Bacteriana em tomateiro sob cultivo protegido no Município de Iranduba-AM.
Este trabalho objetiva avaliar a incidência de murcha bacteriana em tomateiro plantado sucessivamente, em sistema de cultivo protegido, na região de Iranduba ? AM
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