93 research outputs found
Interleukin-13 Genetic Variants, Household Carpet Use and Childhood Asthma
10.1371/journal.pone.0051970PLoS ONE81
Genome-wide association study for Atopy and Allergic Rhinitis in a Singapore Chinese population
10.1371/journal.pone.0019719PLoS ONE65
Differential Metabolite Profiles during Fruit Development in High-Yielding Oil Palm Mesocarp
10.1371/journal.pone.0061344PLoS ONE84
QCD Glueball Regge Trajectories and the Pomeron
We report a glueball Regge trajectory emerging from diagonalizing a confining
Coulomb gauge Hamiltonian for constituent gluons. Using a BCS vacuum ansatz and
gap equation, the dressed gluons acquire a mass, of order 800 , providing
the quasiparticle degrees of freedom for a TDA glueball formulation. The TDA
eigenstates for two constituent gluons have orbital, , excitations with a
characteristic energy of 400 revealing a clear Regge trajectory for
, where is the total (sum) gluon spin.
Significantly, the glueball spectrum coincides with the Pomeron given
by . Finally, we also ascertain that lattice data
supports our result, yielding an average intercept of 1.1 in good agreement
with the Pomeron.Comment: 10 pages, 4 ps figure
Pharmacogenomic associations of adverse drug reactions in asthma: systematic review and research prioritisation
A systematic review of pharmacogenomic studies capturing adverse drug reactions (ADRs) related to asthma medications was undertaken, and a survey of Pharmacogenomics in Childhood Asthma (PiCA) consortia members was conducted. Studies were eligible if genetic polymorphisms were compared with suspected ADR(s) in a patient with asthma, as either a primary or secondary outcome. Five studies met the inclusion criteria. The ADRs and polymorphisms identified were change in lung function tests (rs1042713), adrenal suppression (rs591118), and decreased bone mineral density (rs6461639) and accretion (rs9896933, rs2074439). Two of these polymorphisms were replicated within the paper, but none had external replication. Priorities from PiCA consortia members (representing 15 institution in eight countries) for future studies were tachycardia (SABA/LABA), adrenal suppression/crisis and growth suppression (corticosteroids), sleep/behaviour disturbances (leukotriene receptor antagonists), and nausea and vomiting (theophylline). Future pharmacogenomic studies in asthma should collect relevant ADR data as well as markers of efficacy
Undiagnosed Phenylketonuria Can Exist Everywhere: Results From an International Survey
peer reviewedMany countries do not have a newborn screening (NBS) program, and immigrants from such countries are at risk for late diagnosis of phenylketonuria (PKU). In this international survey, 52 of 259 patients (20%) with late diagnosed PKU were immigrants, and 145 of the 259 (55%) were born before NBS or in a location without NBS. © 2021 The Author
Conformational IgE Epitope Mapping of der p 2 and the Evaluations of Two Candidate Hypoallergens for Immunotherapy
10.1038/s41598-018-21792-1Scientific Reports81339
Systematic review of the epidemiology of acne vulgaris
10.1038/s41598-020-62715-3Scientific Reports101575
Utilization of healthcare resources for asthma in Singapore: Demographic features and trends
Asian Pacific Journal of Allergy and Immunology162-357-68APJI
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