H. T. Tsiang: A Critical Overview of His Work in Literary and Social Context

A Chinese exile in the United States, H. T. Tsiang (1899-1971) wrote several books in English that represent pioneer works in the canon of Asian American literature. Although few know his work today, Tsiang is one of the earliest and most prolific innovators of Asian American literature, anticipating some of the appropriative methods, formal techniques, and critical strategies that have come to characterize the tradition

Strategic Hybridity in Early Chinese and Japanese American Literature

Early Chinese and Japanese American male writers between 1887 and 1938 such as Yan Phou Lee, Yung Wing, Sadakichi Hartmann, Yone Noguchi, and H. T. Tsiang accessed dominant US publishing markets and readerships by presenting themselves and their works as cultural hybrids that strategically blended enticing Eastern content and forms with familiar Western language and structures. Yan Phou Lee perpetrated cross-cultural comparisons that showed that Chinese were not unlike Europeans and Americans. Yung Wing appropriated and then transformed dominant American autobiographical narratives to recuperate Chinese character. Sadakichi Hartmann and Yone Noguchi combined poetic traditions from Japan, Europe, and America in order to define a modernism that included cosmopolitans such as themselves. And H. T. Tsiang promoted Marxist world revolution by experimenting with fusions of Eastern and Western elements with leftist ideology. Although these writers have been discounted by some critics as overly compromising in their attempts to reach Western readers, they accomplished laudable cultural work in their particular historical circumstances and provide insights into the varied and complicated negotiations of Asian American identity during the exclusion era

On Recovering Early Asian American Literature

Beginning in the early 1970s, scholars have been recovering an Asian American literary archive. The first anthologies of Asian American literature defined the field in divergent ways. Some focused on US-born writers and a politics of cultural nationalism. Others embraced a wider range of writers and a variety of political positions. The second wave of anthologies and scholarly discussions reacted against more limited views of Asian American literature and extended the field to encompass more women writers, genres such as poetry and drama, works written before the 1960s, and authors from beyond those of East Asian descent. Depending on the particular project, recovery has meant unearthing forgotten writings, revaluing discounted or discredited texts, or rethinking the sociopolitical context of works. Recovery continues today in print and digital editions released by both independent and mainstream publishers. Questions remain about which authors and works deserve recovery, and the stakes are high since inclusion in a canon can serve as a proxy for inclusion in a culture.https://scholarworks.smith.edu/eng_books/1002/thumbnail.jp

H. T. Tsiang: Literary Innovator and Activist

A Chinese exile in the United States, H. T. Tsiang (1899-1971) wrote several books in English that represent pioneer works in the canon of Asian American literature. Following the principle of nalai zhuyi, or strategic appropriation from other writers, Tsiang created a new, hybridized literature by reworking formal and thematic elements from classical and contemporary Chinese literature, the proletarian works of 1920s and 1930s America, and western classics like the plays of William Shakespeare. Although few know his work today, Tsiang is one of the earliest and most prolific innovators of Asian American literature, anticipating some of the appropriative methods, formal techniques, and critical strategies that have come to characterize the tradition

ENG199: Methods in Literary Study

Syllabus for gateway course for English majo

Controlled-Release of Tegretol-XR for Treatment of Epileptic Seizures

Fifty million people around the world are currently affected by epilepsy. Fortunately, the disease responds to treatment 70% of the time, but many of the medications prescribed require multiple dosages per day. To ensure patient compliance, prevent adverse consequences due to missed dosing, and to enhance medicative convenience for the patient, Tegretol has engineered as extended-release pill, Tegretol-XR, which delivers carbamazepine at a nearly constant rate for a twelve hour time period. The design of these tablets involves a drug infused matrix surrounded by an insoluble shell, with a small orifice to allow drug release. When water diffuses through the orifice, the interior pill matrix saturates, and carbamazepine begins to elute out of the orifice until depletion, a process that is designed to take twelve hours. Using COMSOL, a Tegretol-XR tablet was modeled as a 2D rectangular, axisymmetrical slab. Researched diffusivity constants were found to precisely model the water and drug flow into and out of the pills. The diffusion of the drug is coupled with the concentration of water, and as the water infuses into the pill, the diffusivity of the drug is altered, ultimately leading to a sustained release of carbamazepine over the allotted twelve hours. Results from our model indicate that drug release closely follows ideal release kinetics and keeps an ample amount of drug in the bloodstream at all times. It was found that altering the orifice size by 5% resulted in changes of up to 16% in final average drug concentration, implicating that this is the most sensitive variable analyzed. Variables like water diffusivity were much less influential to the final solution. Our model of Tegretol-XR gives epileptic patients the option of taking only two pills a day, and thus, significantly lowers the risk of a missed dose

Acute liver toxicity with ifosfamide in the treatment of sarcoma: a case report

<p>Abstract</p> <p>Introduction</p> <p>Ifosfamide is a chemotherapy agent infrequently associated with liver toxicity. To the best of our knowledge, this report is the first to describe serious liver toxicity associated with ifosfamide used in combination with doxorubicin that caused acute but fully reversible liver failure and encephalopathy. This report reviews the possible mechanisms by which ifosfamide causes this adverse effect.</p> <p>Case report</p> <p>A 61-year-old Caucasian woman who presented with an inoperable right neck mass due to synovial sarcoma was treated with standard-dose ifosfamide and doxorubicin. Within 24 hours of completing the first cycle of chemotherapy, she developed significant derangements in liver function, with a 250-fold increase in transaminase and associated synthetic function impairment and encephalopathy. No other causes of liver failure were identified. Both biochemical tests and encephalopathy were reversed after supportive management and treatment with <it>N</it>-acetylcysteine. No liver toxicity was observed with subsequent cycles of chemotherapy with doxorubicin alone.</p> <p>Conclusion</p> <p>This case highlights the possibility that chemotherapy agents can cause rare and idiosyncratic toxicities, so physicians must be vigilant for drug reactions, especially when patients do not respond to usual treatment.</p

Acute liver toxicity with ifosfamide in the treatment of sarcoma: a case report

<p>Abstract</p> <p>Introduction</p> <p>Ifosfamide is a chemotherapy agent infrequently associated with liver toxicity. To the best of our knowledge, this report is the first to describe serious liver toxicity associated with ifosfamide used in combination with doxorubicin that caused acute but fully reversible liver failure and encephalopathy. This report reviews the possible mechanisms by which ifosfamide causes this adverse effect.</p> <p>Case report</p> <p>A 61-year-old Caucasian woman who presented with an inoperable right neck mass due to synovial sarcoma was treated with standard-dose ifosfamide and doxorubicin. Within 24 hours of completing the first cycle of chemotherapy, she developed significant derangements in liver function, with a 250-fold increase in transaminase and associated synthetic function impairment and encephalopathy. No other causes of liver failure were identified. Both biochemical tests and encephalopathy were reversed after supportive management and treatment with <it>N</it>-acetylcysteine. No liver toxicity was observed with subsequent cycles of chemotherapy with doxorubicin alone.</p> <p>Conclusion</p> <p>This case highlights the possibility that chemotherapy agents can cause rare and idiosyncratic toxicities, so physicians must be vigilant for drug reactions, especially when patients do not respond to usual treatment.</p

What can different types of linguistic data teach us on evidentiality?

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