Considerations on Different Features of Local Seismic Effect Numerical Simulations: The Case Studied of Castelnuovo Garfagnana

Numerical studies of local seismic effects are commonly carried out by means of 1D and 2D simulations performed in order to evaluate amplification effects in terms of acceleration response spectra and amplification factors. Such approaches can be easily compared with prescriptions from technical provisions as Eurocode 8 that lead design activity whenever a poor soil characterization is available. When suitable investigation campaigns and regional hazard studies are undertaken accurate studies on local seismic effects can be developed. As a matter of fact, soil high heterogeneity and variability, input motion features and geometrical irregularities of soil layer boundaries heavily affect seismic soil response and frequently cause different damages in urban areas. For that reason, although just from deterministic standpoint, spatial variation of amplification effects has been investigated in order to understand how much numerical simulation experiences in amplification previsions can improve simplified approaches suggested by technical codes. In this study Castelnuovo Garfagnana town (Italy) has been studied by means of numerical simulation. Results have been discussed focusing on those aspects which mainly interpret the physical phenomenon that mostly affect seismic local amplification effects

Opažanje α-raspada 10B i 12B u 9Be +7Li reakcijama

The 10B and 12B excitation energy spectra have been obtained from the inclusive and coincident measurements of the 9Be +7Li reactions at Ebeam=52 MeV. Contributions of the 10B states below 10 MeV and of the 12B states below 16 MeV excitation have been resolved. 10B states at 4.77 and 6.56 MeV as well as groups of states around 5.1 and 6 MeV decaying into α +6Li, and of the state at 7.0 MeV decaying into α +6Li∗ have been found. These measurements give the first evidence for α +8Li decay of the 12B states. In our data, there is no evidence for the α +8Li∗ (0.98 MeV) and α +8Li∗ (2.26 MeV) decays of 12B. The influence of α-decaying 12B states on the cross section of the astrophysically important 8Li(α,n)11B reaction is discussed.Odredili smo uzbudne energijske spektre 10B i 12B uključivim i sudesnim mjerenjima reakcije 9Be+7Li na Esnop=52 MeV. Razdvojili smo doprinose stanja 10B ispod 10 MeV i stanja 12B ispod 16 MeV. Našli smo raspade stanja 10B na 4.77 i 6.56 MeV i grupa stanja oko 5.1 i oko 6 MeV u α +6Li, i stanja na 7.0 MeV u α +6Li∗ . Ovo su prva mjerenja u kojima se nalazi α +8Li raspad viših stanja 12B. Naši podaci ne ukazuju prisutnost α +8Li∗ (0.98 MeV) i α +8Li∗ (2.26 MeV) raspada 12B. Raspravljamo utjecaj stanja 12B koja podliježu α-raspadu na udarne presjeke astrofizički važne reakcije 8Li(α,n)11B

Opažanje α-raspada 10B i 12B u 9Be +7Li reakcijama

The 10B and 12B excitation energy spectra have been obtained from the inclusive and coincident measurements of the 9Be +7Li reactions at Ebeam=52 MeV. Contributions of the 10B states below 10 MeV and of the 12B states below 16 MeV excitation have been resolved. 10B states at 4.77 and 6.56 MeV as well as groups of states around 5.1 and 6 MeV decaying into α +6Li, and of the state at 7.0 MeV decaying into α +6Li∗ have been found. These measurements give the first evidence for α +8Li decay of the 12B states. In our data, there is no evidence for the α +8Li∗ (0.98 MeV) and α +8Li∗ (2.26 MeV) decays of 12B. The influence of α-decaying 12B states on the cross section of the astrophysically important 8Li(α,n)11B reaction is discussed.Odredili smo uzbudne energijske spektre 10B i 12B uključivim i sudesnim mjerenjima reakcije 9Be+7Li na Esnop=52 MeV. Razdvojili smo doprinose stanja 10B ispod 10 MeV i stanja 12B ispod 16 MeV. Našli smo raspade stanja 10B na 4.77 i 6.56 MeV i grupa stanja oko 5.1 i oko 6 MeV u α +6Li, i stanja na 7.0 MeV u α +6Li∗ . Ovo su prva mjerenja u kojima se nalazi α +8Li raspad viših stanja 12B. Naši podaci ne ukazuju prisutnost α +8Li∗ (0.98 MeV) i α +8Li∗ (2.26 MeV) raspada 12B. Raspravljamo utjecaj stanja 12B koja podliježu α-raspadu na udarne presjeke astrofizički važne reakcije 8Li(α,n)11B

Problems Associated With the Assessment of Local Site Effects Through a Multidisciplinary Integrated Study: The Case of Fivizzano’s Town (Italy)

The evaluation of local site effects, by means of ground response analyses, is a very complex and difficult task, which requires a multidisciplinary approach. This is operative philosophy expressed by VEL Project (Valutazione degli Effetti Locali), sponsored by Tuscany Region, to the aim to seismic risk characterization in the main seismic areas (i.e. Garfagnana, Lunigiana, Amiata, Valtiberina and Mugello). One of the most important urban centres, involved in the multidisciplinary activity of the VEL project, is certainly the town of Fivizzano located nearby the city of Massa, which was strongly damaged during the earthquake of September 1920 (the strongest seismic event occurred in Northern Apennines in the latest centuries). Remarkably good macroseismic information is available about the destructive impact yielded at Fivizzano by this earthquake (e.g. number of casualties, level of damage of buildings, etc). The main objective of this paper is to identify the occurrence of possible local site effects in the Fivizzano’s area following the 1920 earthquake and to quantify them by means of one and two-dimensional site response analysis. The input data required for study were obtained through a comprehensive geological survey and a multi disciplinary underground exploration of the area

10Be i molekulska stanja

The 10Be excitation energy spectra have been obtained from the inclusive and coincident measurements of the reactions: 7Li +7Li at E0 = 8 and 30 MeV and 9Be +7Li at E0 = 52 MeV. Contributions of the 10Be states below 12 MeV in excitation have been observed. Decays of the states at 9.6, 10.2 and 11.8 into a +6He and, for the first time, into a +6He* have been found. The results are discussed in addition to the other experimental data and recent theoretical predictions. Proposals for future measurements to search for exotic structures in carbon nuclei are also made.Proučavamo ekscitacijske energijske spektre 10Be iz inkluzivnih i koincidentnih mjerenja reakcija 7Li +7Li na E0 = 8 i 30 MeV, te 9Be +7Li na E0 = 52 MeV. Opaženi su doprinosi stanja 10Be u energiji uzbude do 12 MeV. Nađeni su raspadi stanja na 9.6, 10.2 i 11.8 MeV na α +6He te, po prvi put, na α +6He∗. Ovi se rezultati razmatraju zajedno s ostalim eksperimentalnim podacima i novijim teorijskim predviđanjima. Predlažu se buduća mjerenja u kojima bi se tražila stanja lakih jezgara egzotične građe

10Be i molekulska stanja

The 10Be excitation energy spectra have been obtained from the inclusive and coincident measurements of the reactions: 7Li +7Li at E0 = 8 and 30 MeV and 9Be +7Li at E0 = 52 MeV. Contributions of the 10Be states below 12 MeV in excitation have been observed. Decays of the states at 9.6, 10.2 and 11.8 into a +6He and, for the first time, into a +6He* have been found. The results are discussed in addition to the other experimental data and recent theoretical predictions. Proposals for future measurements to search for exotic structures in carbon nuclei are also made.Proučavamo ekscitacijske energijske spektre 10Be iz inkluzivnih i koincidentnih mjerenja reakcija 7Li +7Li na E0 = 8 i 30 MeV, te 9Be +7Li na E0 = 52 MeV. Opaženi su doprinosi stanja 10Be u energiji uzbude do 12 MeV. Nađeni su raspadi stanja na 9.6, 10.2 i 11.8 MeV na α +6He te, po prvi put, na α +6He∗. Ovi se rezultati razmatraju zajedno s ostalim eksperimentalnim podacima i novijim teorijskim predviđanjima. Predlažu se buduća mjerenja u kojima bi se tražila stanja lakih jezgara egzotične građe

Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations

Details of sequence profiles for each NCWS subject. (XLSX 47 kb

Comparing the effects of augmented virtual reality treadmill training versus conventional treadmill training in patients with stage II-III Parkinson’s disease: the VIRTREAD-PD randomized controlled trial protocol

BackgroundIntensive treadmill training (TT) has been documented to improve gait parameters and functional independence in Parkinson’s Disease (PD), but the optimal intervention protocol and the criteria for tailoring the intervention to patients’ performances are lacking. TT may be integrated with augmented virtual reality (AVR), however, evidence of the effectiveness of this combined treatment is still limited. Moreover, prognostic biomarkers of rehabilitation, potentially useful to customize the treatment, are currently missing. The primary aim of this study is to compare the effects on gait performances of TT + AVR versus TT alone in II-III stage PD patients with gait disturbance. Secondary aims are to assess the effects on balance, gait parameters and other motor and non-motor symptoms, and patient’s satisfaction and adherence to the treatment. As an exploratory aim, the study attempts to identify biomarkers of neuroplasticity detecting changes in Neurofilament Light Chain concentration T0-T1 and to identify prognostic biomarkers associated to blood-derived Extracellular Vesicles.MethodsSingle-center, randomized controlled single-blind trial comparing TT + AVR vs. TT in II-III stage PD patients with gait disturbances. Assessment will be performed at baseline (T0), end of training (T1), 3 (T2) and 6 months (T3, phone interview) from T1. The primary outcome is difference in gait performance assessed with the Tinetti Performance-Oriented Mobility Assessment gait scale at T1. Secondary outcomes are differences in gait performance at T2, in balance and spatial–temporal gait parameters at T1 and T2, patients’ satisfaction and adherence. Changes in falls, functional mobility, functional autonomy, cognition, mood, and quality of life will be also assessed at different timepoints. The G*Power software was used to estimate a sample size of 20 subjects per group (power 0.95, α < 0.05), raised to 24 per group to compensate for potential drop-outs. Both interventions will be customized and progressive, based on the participant’s performance, according to a predefined protocol.ConclusionThis study will provide data on the possible superiority of AVR-associated TT over conventional TT in improving gait and other motor and non-motor symptoms in persons with PD and gait disturbances. Results of the exploratory analysis could add information in the field of biomarker research in PD rehabilitation

Eksperimentalni dokazi (pokazatelji) molekulske strukture lakih jezgri

Experimental studies of the cluster structures in 9,10Be and 13,14C have been performed. Evidence for the α+5He decay of 9Be excited states, α+6He decays of 10Be∗ , α+9Be decay of 13C ∗ and for the decays of 14C ∗ into α+10Be were found. These decay processes indicate the cluster structures of the excited states. The results are compared with recent suggestions for the presence of molecule-like structures based upon α-particles and valence neutrons in Be and C isotopes.Eksperimentalno smo proučavali nakupinske strukture u 9,10Be i 13,14C. Našli smo α+5He raspad uzbuđenog stanja 9Be, α+6He raspad 10Be∗ , α+9Be raspad 13C ∗ te raspad 14C ∗ u α+10Be. Ovi procesi ukazuju na nakupinske strukture uzbuđenih stanja tih jezgri. Ishode mjerenja uspoređujemo s novim objašnjenjima o prisutnosti molekulama-sličnih struktura zasnovanim na α-česticama i valentnim neutronima u izotopima Be i C

Eksperimentalni dokazi (pokazatelji) molekulske strukture lakih jezgri

Experimental studies of the cluster structures in 9,10Be and 13,14C have been performed. Evidence for the α+5He decay of 9Be excited states, α+6He decays of 10Be∗ , α+9Be decay of 13C ∗ and for the decays of 14C ∗ into α+10Be were found. These decay processes indicate the cluster structures of the excited states. The results are compared with recent suggestions for the presence of molecule-like structures based upon α-particles and valence neutrons in Be and C isotopes.Eksperimentalno smo proučavali nakupinske strukture u 9,10Be i 13,14C. Našli smo α+5He raspad uzbuđenog stanja 9Be, α+6He raspad 10Be∗ , α+9Be raspad 13C ∗ te raspad 14C ∗ u α+10Be. Ovi procesi ukazuju na nakupinske strukture uzbuđenih stanja tih jezgri. Ishode mjerenja uspoređujemo s novim objašnjenjima o prisutnosti molekulama-sličnih struktura zasnovanim na α-česticama i valentnim neutronima u izotopima Be i C