Electric Two-Wheelers in China: Analysis ofEnvironmental, Safety, and Mobility Impacts

Electric powered two-wheel bicycles, while extremely popular in China, have been recently banned by policy makers due to safety, congestion, and environmental concerns. This study investigates the tremendous growth of electric two wheel bicycles in China and compares and quantifies their environmental and safety impacts with the impacts of alternative modes of transportation, such as traditional bicycles, public transportation, or personal cars. The research also analyzes the benefits of electric two wheel bicycles, such as increased mobility and access to opportunities. Additionally, the author looks at the impacts of prohibiting the use of electric bicycles. Two case studies are carried out in Kunming and Shanghai, cities that have similar electric bicycle use but with very distinct differences

Riding an e-scooter at nighttime is more dangerous than at daytime

With rapidly increasing e-scooter usage in the United States [1], a growing number of studies aim to understand the safety aspect of these emerging modes. The existing literature has a limited understanding of time-of-day and seasonal patterns of e-scooter crashes. While many e-scooter safety policies are based on the number of crashes [2, 3], accounting for exposure provides a measure of risk to inform effective preventive strategies [4]. This study focuses on motor-vehicle involved crashes since they constitute the most severe and fatal injuries. We compared daytime and nighttime motor-vehicle involved e-scooter crashes and combined them with micromobility trip data to generate exposure variables and estimate crash risk. The key research question of this paper is as follows: 1. Are crashes or crash rates disproportionately higher at night than in the day? [From: Introduction

Health hazards of China’s lead-acid battery industry: a review of its market drivers, production processes, and health impacts

Despite China’s leaded gasoline phase out in 2000, the continued high rates of lead poisoning found in children’s blood lead levels reflect the need for identifying and controlling other sources of lead pollution. From 2001 to 2007, 24% of children in China studied (N = 94,778) were lead poisoned with levels exceeding 100 μg/L. These levels stand well above the global average of 16%. These trends reveal that China still faces significant public health challenges, with millions of children currently at risk of lead poisoning. The unprecedented growth of China’s lead-acid battery industry from the electric bike, automotive, and photovoltaic industries may explain these persistently high levels, as China remains the world’s leading producer, refiner, and consumer of both lead and lead-acid batteries. This review assesses the role of China’s rising lead-acid battery industry on lead pollution and exposure. It starts with a synthesis of biological mechanisms of lead exposure followed by an analysis of the key technologies driving the rapid growth of this industry. It then details the four main stages of lead battery production, explaining how each stage results in significant lead loss and pollution. A province-level accounting of each of these industrial operations is also included. Next, reviews of the literature describe how this industry may have contributed to mass lead poisonings throughout China. Finally, the paper closes with a discussion of new policies that address the lead-acid battery industry and identifies policy frameworks to mitigate exposure. This paper is the first to integrate the market factors, production processes, and health impacts of China’s growing lead-acid battery industry to illustrate its vast public health consequences. The implications of this review are two-fold: it validates calls for a nationwide assessment of lead exposure pathways and levels in China as well as for a more comprehensive investigation into the health impacts of the lead-acid battery industry. The continuous growth of this industry signals the urgent need for effective regulatory action to protect the health and lives of China’s future generations

Differences of Cycling Experiences and Perceptions between E-Bike and Bicycle Users in the United States

E-bikes are bicycles that provide pedal-assistance to aid people in cycling. Because of the potential of promoting sustainable transportation, more attention has been focused on the e-bike market. This paper investigates the differences of the cycling experience and perceptions between e-bike and conventional bicycle users, using samples drawn from independent bicycle dealer customers. A total of 806 respondents in the United States took the on-line survey, including 363 e-bike-owning respondents. The results show that e-bikes play a more important role in utilitarian travel, such as commuting and running errands, compared to a conventional bicycle. Conventional bicycle-owning respondents use their bicycles more for recreation and exercise. Also, e-bike owners tend to bike longer distances and take more trips per week. Both e-bike respondents and bicycle respondents stated that improved health was a key factor for cycling, while Millennials and Generation X respondents cycle to save time and improve the environment. Finally, an ordered logit model is proposed for evaluating factors that influence interest in future e-bike ownership. Travel purpose, e-bike familiarity, annual household income, and education level are statistically significant factors in the model. These findings begin to provide insight and a profile of potential new markets for e-bikes in the United States

Factors influencing the choice of shared bicycles and shared electric bikes in Beijing

AbstractChina leads the world in both public bikeshare and private electric bike (e-bike) growth. Current trajectories indicate the viability of deploying large-scale shared e-bike (e-bikeshare) systems in China. We employ a stated preference survey and multinomial logit to model the factors influencing the choice to switch from an existing transportation mode to bikeshare or e-bikeshare in Beijing. Demand is influenced by distinct sets of factors: the bikeshare choice is most sensitive to measures of effort and comfort while the e-bikeshare choice is more sensitive to user heterogeneities. Bikeshare demand is strongly negatively impacted by trip distance, temperature, precipitation, and poor air quality. User demographics however do not factor strongly on the bikeshare choice, indicating the mode will draw users from across the social spectrum. The e-bikeshare choice is much more tolerant of trip distance, high temperatures and poor air quality, though precipitation is also a highly negative factor. User demographics do play a significant role in e-bikeshare demand. Analysis of impact to the existing transportation system finds that both bikeshare and e-bikeshare will tend to draw users away from the “unsheltered modes”, walk, bike, and e-bike. Although it is unclear if shared bikes are an attractive “first-and-last-mile solution”, it is clear that e-bikeshare is attractive as a bus replacement

Effects of neonatal amygdala or hippocampus lesions on resting brain metabolism in the macaque monkey: A microPET imaging study

Longitudinal analysis of animals with neonatal brain lesions enables the evaluation of behavioral changes during multiple stages of development. Interpretation of such changes, however, carries the caveat that permanent neural injury also yields morphological and neurochemical reorganization elsewhere in the brain that may lead either to functional compensation or to exacerbation of behavioral alterations. We have measured the long-term effects of selective neonatal brain damage on resting cerebral glucose metabolism in nonhuman primates. Sixteen rhesus monkeys (Macaca mulatta) received neurotoxic lesions of either the amygdala (n = 8) or hippocampus (n = 8) when they were two weeks old. Four years later, these animals, along with age- and experience-matched sham-operated control animals (n = 8), were studied with high-resolution positron emission tomography (microPET) and 2-deoxy-2[¹⁸F]fluoro-d-glucose ([¹⁸F]FDG) to detect areas of altered metabolism. The groups were compared using an anatomically-based region of interest analysis. Relative to controls, amygdala-lesioned animals displayed hypometabolism in three frontal lobe regions, as well as in the neostriatum and hippocampus. Hypermetabolism was also evident in the cerebellum of amygdala-lesioned animals. Hippocampal-lesioned animals only showed hypometabolism in the retrosplenial cortex. These results indicate that neonatal amygdala and hippocampus lesions induce very different patterns of long-lasting metabolic changes in distant brain regions. These observations raise the possibility that behavioral alterations in animals with neonatal lesions may be due to the intended damage, to consequent brain reorganization or to a combination of both factors

A Systems Engineering Approach to Aircraft Kinetic Kill Countermeasures Technology: Development of an Active Aircraft Defense System for the C/KC-135 Aircraft

Modern Surface to Air Missiles (SAMs) present a significant threat to today\u27s military and civilian aircraft. Current countermeasure systems such as flares and chaff rely on decoying the missile threat and do not provide adequate protection against advanced computerized missiles (Schaffer, 1993:1). An aircraft defense system that actively seeks out and defeats an incoming missile by placing a physical barrier in the missile\u27s path offers a promising alternative to current countermeasures technology. This thesis reports the preliminary design of an active aircraft defense system for the protection of the C/KC-135 aircraft from SAMs. The developed system utilizes a kinetic kill mechanism to protect the aircraft from shoulder launched missiles while the aircraft is in the takeoff and climb-out configurations. Both smart anti-missile expendables and dumb projectile expendables are evaluated. The iterative Systems Engineering approach is used to narrow the solution set to the optimal design. The final outcome is the refined design of two candidate aircraft defense system employing a kinetic kill mechanism. Both systems utilize a modified ultra-violet tracker and employ one of two types of nets, one made out of Detonation Cord and the other made out of Spectra

GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues

This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) and Diabetes UK. The authors declare no conflicts of interest. This article includes supplemental data. Please visit http://www.fasebj.org to obtain this information.Peer reviewedPublisher PD

Utilization of Intensive Care Unit Nutrition Consultation Is Associated With Reduced Mortality

BackgroundThe aim of this project was to investigate the prevalence of nutrition consultation (NC) in U.S. intensive care units (ICUs) and to examine its association with patient outcomes.MethodsData from the Healthcare Cost and Utilization Project’s state inpatient databases was utilized from 2010 â 2014. A multilevel logistic regression model was used to evaluate the relationship between NC and clinical outcomes.ResultsInstitutional ICU NC rates varied significantly (mean: 14%, range: 0.1%â 73%). Significant variation among underlying disease processes was identified, with burn patients having the highest consult rate (P < 0.001, mean: 6%, range: 2%â 25%). ICU patients who received NC had significantly lower inâ hospital mortality (odds ratio [OR] 0.59, 95% confidence interval [CI] 0.48â 0.74, P < 0.001), as did the subset with malnutrition (OR 0.72, 95% CI 0.53â 0.99, P = 0.047) and the subset with concomitant physical therapy consultation (OR 0.53, 95% CI 0.38â 0.74, P < 0.001). NC was associated with significantly lower rates of intubation, pulmonary failure, pneumonia, and gastrointestinal bleeding (P < 0.05). Furthermore, patients who received NC were more likely to receive enteral or parenteral nutrition (ENPN) (OR 1.8, 95% CI 1.4â 2.3, P < 0.001). Patients who received followâ up NC were even more likely to receive ENPN (OR 3.0, 95% CI 2.1â 4.2, P < 0.001).ConclusionsRates of NC were low in critically ill patients. This study suggests that increased utilization of NC in critically ill patients may be associated with improved clinical outcomes.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154413/1/jpen1534_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154413/2/jpen1534.pd

Tackling dementia together via the Australian dementia network (ADNeT): A summary of initiatives, progress and plans

In 2018, the Australian Dementia Network (ADNeT) was established to bring together Australia\u27s leading dementia researchers, people with living experience and clinicians to transform research and clinical care in the field. To address dementia diagnosis, treatment, and care, ADNeT has established three core initiatives: the Clinical Quality Registry (CQR), Memory Clinics, and Screening for Trials. Collectively, the initiatives have developed an integrated clinical and research community, driving practice excellence in this field, leading to novel innovations in diagnostics, clinical care, professional development, quality and harmonization of healthcare, clinical trials, and translation of research into practice. Australia now has a national Registry for Mild Cognitive Impairment and dementia with 55 participating clinical sites, an extensive map of memory clinic services, national Memory and Cognition Clinic Guidelines and specialized screening for trials sites in five states. This paper provides an overview of ADNeT\u27s achievements to date and future directions. With the increase in dementia cases expected over coming decades, and with recent advances in plasma biomarkers and amyloid lowering therapies, the nationally coordinated initiatives and partnerships ADNeT has established are critical for increased national prevention efforts, co-ordinated implementation of emerging treatments for Alzheimer\u27s disease, innovation of early and accurate diagnosis, driving continuous improvements in clinical care and patient outcome and access to post-diagnostic support and clinical trials. For a heterogenous disorder such as dementia, which is now the second leading cause of death in Australia following cardiovascular disease, the case for adequate investment into research and development has grown even more compelling