SWOT Analysis of the Application of International Standard ISO 14001 in the Chinese Context. A Case Study of Guangdong Province

Industry has long been one of the most important drivers of Chinese economic growth. In order to improve the environmental footprint of industrial areas, Chinese authorities have established mechanisms of environmental control in the internal management processes of companies. In this regard, the international standard ISO 14001 for environmental management systems is the management tool that has had widest adoption among Chinese companies since its creation in 1996. The main purposes of the paper are to investigate the available international and national statistics on the adoptionof ISO 14001 in China, and present opinions on ISO 14001 of the 72 representatives of small and medium enterprises and multinational companies of Guangdong province that participated to the workshop New tools and standards to advance and measure corporate sustainability, held in Guangzhou on 26 January 2018. The analysis of strengths, weaknesses, opportunities and threats (SWOT) was adopted as the research method to collect opinions on the ISO 14001 standard. Participants were asked to discuss strengths, weaknesses, threats and opportunities considering four business aspects: sustainability, internal processes, stakeholder engagement, and resource management. Our findings indicate that companies fully embraced ISO 14001 and recognized the necessity of a standardized approach to identify environmental aspects. On the other hand, they also expressed concern about aspects such as the certification cost, the focus on certification itself and not on the improvement of environmental performance, and the lack of integration with sustainability tools such as life cycle assessment (LCA) and other sustainability paradigms such as circular economy and corporate social responsibility (CSR)

Present-day activity and seismic potential of the north Qinling fault, southern ordos block, central China, as revealed from GPS data and seismicity

The North Qinling Fault, located at the boundary of the North China Block and the South China Block, represents an important tectonic structure between the Weihe Basin and the Qinling Mountains, and controls the subsidence and expansion of the Weihe Basin. This fault has been highly active and has caused strong earthquakes since the Holocene and in a pre-seismic stage currently, as indicated by the many paleoearthquake traces found along it. To determine the present-day activity and seismic potential of the North Qinling Fault, by inverting GPS data, we produced fault locking depth, slip rate, and regional strain fields maps; moreover, based on seismicity, we produced a seismic b-value map. Combining this information with modern seismicity, we were able to comprehensively analyze the seismic potential of different fault segments. Our inversion of GPS data showed that the slip rate of the western segment of the fault (Qingjiangkou–Xitangyu) and the correspondent locking depth are 1.33 mm/a and 13.54 km, respectively, while the slip rate of the middle segment (Xitangyu–Fengyukou) and the correspondent locking depth are 0.45 mm/a and 8.58 km, respectively; finally, the slip rate of the eastern segment (Xitangyu–Daiyu) and the correspondent locking depth are 0.36 mm/a and 21.46 km, respectively. The locking depths of the western and middle segments of the fault are shallower than 90% of the seismic cutoff depth, while the locking depth of the eastern segment of the fault is similar to 90% of the seismic cutoff depth, indicating that “deep creep” occurs in the western and middle segments, while the eastern segment is locked. Modern small earthquakes have involved the western and middle segments of the fault, while the eastern segment has acted as a seismic gap with weak seismicity, characterized by a higher shear strain value and a lower b-value. These characteristics reflect the relationship between the locking depth and seismicity distribution. The results of our comprehensive analysis, combined with field geological surveys, show that the eastern segment of the North Qinling Fault has a strong seismic potential and is presently locked

Benzo[1,2-b:4,5-b′]difuran-based sensitizers for dye-sensitized solar cells

Two BDF-based organic sensitizers, as first examples for their use in dye-sensitized solar cells, are prepared and characterized. They yield promising power conversion efficiencies of up to 5.5% and high open circuit voltages up to 0.82 V. This work demonstrates that the BDF chromophore acts as an effective donor in organic sensitizers

Targeted Expression of Cre Recombinase Provokes Placental-Specific DNA Recombination in Transgenic Mice

Background: Inadequate placental development is associated with a high incidence of early embryonic lethality and serious pregnancy disorders in both humans and mice. However, the lack of well-defined trophoblast-specific gene regulatory elements has hampered investigations regarding the role of specific genes in placental development and fetal growth. Principal Findings: By random assembly of placental enhancers from two previously characterized genes, trophoblast specific protein a (Tpbpa) and adenosine deaminase (Ada), we identified a chimeric Tpbpa/Ada enhancer that when combined with the basal Ada promoter provided the highest luciferase activity in cultured human trophoblast cells, in comparison with non-trophoblast cell lines. We used this chimeric enhancer arrangement to drive the expression of a Cre recombinase transgene in the placentas of transgenic mice. Cre transgene expression occurred throughout the placenta but not in maternal organs examined or in the fetus. Significance: In conclusion, we have provided both in vitro and in vivo evidence for a novel genetic system to achieve placental transgene expression by the use of a chimeric Tpbpa/Ada enhancer driven transgene. The availability of thi

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

A Hybrid Robust-Learning Architecture for Medical Image Segmentation with Noisy Labels

Deep-learning models require large amounts of accurately labeled data. However, for medical image segmentation, high-quality labels rely on expert experience, and less-experienced operators provide noisy labels. How one might mitigate the negative effects caused by noisy labels for 3D medical image segmentation has not been fully investigated. In this paper, our purpose is to propose a novel hybrid robust-learning architecture to combat noisy labels for 3D medical image segmentation. Our method consists of three components. First, we focus on the noisy annotations of slices and propose a slice-level label-quality awareness method, which automatically generates label-quality scores for slices in a set. Second, we propose a shape-awareness regularization loss based on distance transform maps to introduce prior shape information and provide extra performance gains. Third, based on a re-weighting strategy, we propose an end-to-end hybrid robust-learning architecture to weaken the negative effects caused by noisy labels. Extensive experiments are performed on two representative datasets (i.e., liver segmentation and multi-organ segmentation). Our hybrid noise-robust architecture has shown competitive performance, compared to other methods. Ablation studies also demonstrate the effectiveness of slice-level label-quality awareness and a shape-awareness regularization loss for combating noisy labels

The earthquake probabilities of the Liupanshan fault zone based on the Coulomb stress and friction constitutive law

AbstractAs the forefront of the northeastern margin of the Tibetan Plateau, the Liupanshan area is subjected to significant Cenozoic deformation. Considering the background of historical earthquakes and the current seismic activity, the Liupanshan fault poses a risk of strong earthquakes. This paper analyzes the evolution of Coulomb stress induced by the coseismic and postseismic viscoelastic deformation of six historical strong earthquakes that occurred around the Liupanshan area since the twentieth century. Additionally, based on the disturbance in Coulomb stress and the background seismicity rate, the probability of earthquake occurrence is quantitatively evaluated using the frictional constitutive law. The results indicate that northern section of the Liupanshan fault has higher earthquake potential than the southern section, warranting close attention. These findings serve as a reference for medium- and long-term earthquake forecast and risk assessment in the vicinity of the Liupanshan fault