168 research outputs found
An examination of the relationship between creative potential and personality types among American and Taiwanese college students of teacher education
Previous research has studied the effects of personality on creativity. The present study examined the relationship between personality types and creativity. Creativity was measured by using the Torrance Test of Creative Thinking (TTCT)-Figural, whereas personality type was measured by using Keirsey Temperament Sorter II (KTS II). 57 Americans and 72 Taiwanese college students who specialize in teacher education participated in this study. Consistent with previous research, significant correlation coefficients between the Creativity Index of the TTCT and both the Intuitive (p \u3c .0001) and Perceiving (p = .029) personality types of the KTS II were found. In addition, significant cultural differences in creativity (p = .001) and significant gender differences in personality types (p = .008) were found by multivariate analyses of variance
Learned Quality Enhancement via Multi-Frame Priors for HEVC Compliant Low-Delay Applications
Networked video applications, e.g., video conferencing, often suffer from
poor visual quality due to unexpected network fluctuation and limited
bandwidth. In this paper, we have developed a Quality Enhancement Network
(QENet) to reduce the video compression artifacts, leveraging the spatial and
temporal priors generated by respective multi-scale convolutions spatially and
warped temporal predictions in a recurrent fashion temporally. We have
integrated this QENet as a standard-alone post-processing subsystem to the High
Efficiency Video Coding (HEVC) compliant decoder. Experimental results show
that our QENet demonstrates the state-of-the-art performance against default
in-loop filters in HEVC and other deep learning based methods with noticeable
objective gains in Peak-Signal-to-Noise Ratio (PSNR) and subjective gains
visually
Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness.
Zap70 plays a critical role in normal T cell development and T cell function. However, little is known about how perturbation of allosteric autoinhibitory mechanisms in Zap70 impacts T cell biology. Here, we analyze mice with a hypermorphic Zap70 mutation, W131A, which destabilizes the autoinhibitory conformation of Zap70, rendering the kinase in a semiactive state. W131A mutant mice with wild-type T cell receptor (TCR) repertoires exhibited relatively normal T cell development. However, crossing the W131A mutant mice to OTII TCR transgenic mice resulted in increased negative selection of OTII+ thymocytes and in increased thymic and peripheral T regulatory cells. Strikingly, increased basal TCR signaling was associated with a marked increase in inhibitory receptor expression and with T cells that were relatively refractory to TCR stimulation. PD-1 inhibitory receptor blockade partially reversed T cell unresponsiveness. Collectively, disruption of normal Zap70 autoinhibition engaged negative feedback mechanisms by which negative selection and inhibitory receptors restrain TCR signaling to enforce both central and peripheral tolerance
Genome cloning and genetic diversity of Apple chlorotic leaf spot virus
514-519Apple chlorotic leaf spot virus (ACLSV) with a wide distribution and variability is great threat to apple yield and quality. The systematic research on the occurrence, genetic structure and evolutionary mechanism is important for the prevention of ACLSV. In this study, 360 apple leaf samples were collected from Shanxi province and tested by RT-PCR, and the result showed that the incidence of ACLSV in Shanxi was ranged from 43.59% in Linfen to 68.18% in Wanrong. One new ACLSV isolate (shanxi14-MK368727) was collected from the positive samples, of which the genome (including the 5' and 3' ends) was 7507 bp and encoded 2536 amino acids. Compared with online database, the highest nd identity was between shanxi14 and KJ522693.1, and the lowest was shanxi14 and M58152.1. Phylogenetic analyzed based on genome showed that 25 isolated of ACLSV were divided two groups (Group I and II), which showed that was no significant correlation with geographic location. The selection pressures of POL, MP and CP were tested, the result proved the three genes were under negative selection pressure. The knowledge presented in this study will be useful in for the design of long-term, sustainable management strategies for controlling these viruses
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Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
How pathogenic cluster of differentiation 4 (CD4) T cells in rheumatoid arthritis (RA) develop remains poorly understood. We used Nur77-a marker of T cell antigen receptor (TCR) signaling-to identify antigen-activated CD4 T cells in the SKG mouse model of autoimmune arthritis and in patients with RA. Using a fluorescent reporter of Nur77 expression in SKG mice, we found that higher levels of Nur77-eGFP in SKG CD4 T cells marked their autoreactivity, arthritogenic potential, and ability to more readily differentiate into interleukin-17 (IL-17)-producing cells. The T cells with increased autoreactivity, nonetheless had diminished ex vivo inducible TCR signaling, perhaps reflective of adaptive inhibitory mechanisms induced by chronic autoantigen exposure in vivo. The enhanced autoreactivity was associated with up-regulation of IL-6 cytokine signaling machinery, which might be attributable, in part, to a reduced amount of expression of suppressor of cytokine signaling 3 (SOCS3)-a key negative regulator of IL-6 signaling. As a result, the more autoreactive GFPhi CD4 T cells from SKGNur mice were hyperresponsive to IL-6 receptor signaling. Consistent with findings from SKGNur mice, SOCS3 expression was similarly down-regulated in RA synovium. This suggests that despite impaired TCR signaling, autoreactive T cells exposed to chronic antigen stimulation exhibit heightened sensitivity to IL-6, which contributes to the arthritogenicity in SKG mice, and perhaps in patients with RA
Life cycle economic viability analysis of battery storage in electricity market
Battery storage is essential to enhance the flexibility and reliability of
electric power systems by providing auxiliary services and load shifting.
Storage owners typically gains incentives from quick responses to auxiliary
service prices, but frequent charging and discharging also reduce its lifetime.
Therefore, this paper embeds the battery degradation cost into the operation
simulation to avoid overestimated profits caused by an aggressive bidding
strategy. Based on an operation simulation model, this paper conducts the
economic viability analysis of whole life cycle using the internal rate of
return(IRR). A clustering method and a typical day method are developed to
reduce the huge computational burdens in the life-cycle simulation of battery
storage. Our models and algorithms are validated by the case study of two
mainstream technology routes currently: lithium nickel cobalt manganese oxide
(NCM) batteries and lithium iron phosphate (LFP) batteries. Then a sensitivity
analysis is presented to identify the critical factors that boost battery
storage in the future. We evaluate the IRR results of different types of
battery storage to provide guidance for investment portfolio.Comment: 17 pages, accepted by JP
H2-Stereo: High-Speed, High-Resolution Stereoscopic Video System
High-speed, high-resolution stereoscopic (H2-Stereo) video allows us to
perceive dynamic 3D content at fine granularity. The acquisition of H2-Stereo
video, however, remains challenging with commodity cameras. Existing spatial
super-resolution or temporal frame interpolation methods provide compromised
solutions that lack temporal or spatial details, respectively. To alleviate
this problem, we propose a dual camera system, in which one camera captures
high-spatial-resolution low-frame-rate (HSR-LFR) videos with rich spatial
details, and the other captures low-spatial-resolution high-frame-rate
(LSR-HFR) videos with smooth temporal details. We then devise a Learned
Information Fusion network (LIFnet) that exploits the cross-camera redundancies
to enhance both camera views to high spatiotemporal resolution (HSTR) for
reconstructing the H2-Stereo video effectively. We utilize a disparity network
to transfer spatiotemporal information across views even in large disparity
scenes, based on which, we propose disparity-guided flow-based warping for
LSR-HFR view and complementary warping for HSR-LFR view. A multi-scale fusion
method in feature domain is proposed to minimize occlusion-induced warping
ghosts and holes in HSR-LFR view. The LIFnet is trained in an end-to-end manner
using our collected high-quality Stereo Video dataset from YouTube. Extensive
experiments demonstrate that our model outperforms existing state-of-the-art
methods for both views on synthetic data and camera-captured real data with
large disparity. Ablation studies explore various aspects, including
spatiotemporal resolution, camera baseline, camera desynchronization,
long/short exposures and applications, of our system to fully understand its
capability for potential applications
A public health milestone: China publishes new Physical Activity and Sedentary Behaviour Guidelines
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