Feasibility Study of Tractor-Test Vehicle Technique for Practical Structural Condition Assessment of Beam-Like Bridge Deck

The tractor-test vehicle technique of non-destructive testing for indirect measurement of the modal properties of a bridge deck is revisited in this paper with several improvements for possible practical application to the structural condition assessment of a beam-like bridge deck. The effect of damping of the vehicle-bridge system is considered and the modal properties from only the first vibration mode of the structure will be used for a quick and simple assessment. The two test vehicles are designed to have the same modal frequency and damping ratio but with parameters in the follower No.2 test vehicle proportional to those in the follower No.1 test vehicle. This effectively removes the effect of road surface roughness in the response of an equivalent vehicle such that the error in the subsequent condition assessment is reduced. Through data collected on-site transmitted to the remote computer platform, a simple technique based on the moment-curvature relationship acceptable to practical engineers is adopted for the condition assessment with improvements in the estimation of the element bending stiffness of the deck. Scenarios with different damping, vehicle speed, road surface roughness, and local damages in the bridge structure are studied with or without temperature effect in the measurement. Through numerical simulations and field tests, the tractor-test vehicle technique of non-destructive testing with the proposed modifications and improvements has been demonstrated to give consistently accurate estimates of the element bending stiffness of the bridge deck but with a small error close to the end of the deck

Some recent progress on quark pairings in dense quark and nuclear matter

We give a brief overview on some recent progress in quark pairings in dense quark/nuclear matter mostly developed in the past five years. We focus on following aspects in particular: the BCS-BEC crossover in the CSC phase, the baryon formation and dissociation in dense quark/nuclear matter, the Ginzburg-Landau theory for three-flavor dense matter with $U_{A}$(1) anomaly, and the collective and Nambu-Goldstone modes for the spin-one CSC.Comment: RevTex 4, 25 pages, 9 figures, presented for the KITPC (Kavli Institute for Theoretical Physics China) program "AdS/CFT and Novel Approaches to Hadron and Heavy Ion Physics' in Oct. 11- Dec. 3, 201

How are typical urban sewage treatment technologies going in China: from the perspective of life cycle environmental and economic coupled assessment

Sewage treatment is an important public service, but it consumes a lot of energy and chemicals in the process of removing wastewater pollutants, which may cause the risk of pollution transfer. To find the corresponding hot issues, this paper took the lead in integrating life cycle assessment (LCA) with life cycle costing (LCC) to evaluate four most typical sewage treatment technologies with more than 85% share in China. It is found that anaerobic/anoxic/oxic (AAO) was the optimal treatment scheme with relatively small potential environmental impact and economic load. The normalized results show that the trends of the four technologies on eleven environmental impact categories were basically the same. Marine aquatic ecotoxicity potential accounted for more than 70% of the overall environmental impact. Contribution analysis indicates that electricity and flocculant consumption were the main processes responsible for the environmental and economic burden. Overall, electricity consumption was the biggest hot spot. Sensitivity analysis verifies that a 10% reduction in electricity could bring high benefits to both the economy and the environment. These findings are expected to provide effective feedback on the operation and improvement of sewage treatment

Efficiency assessment of rural domestic sewage treatment facilities by a slacked-based DEA model

In the context of sustainable development, a number of rural domestic sewage treatment facilities had been built in China to solve the problem of rural domestic sewage pollution. The comprehensive, quantitative and objective efficiency assessment of facilities is urgent. This study used a non-radial slacked-based data envelopment analysis model combined with cluster analysis to construct an index system covering multiple aspects, including three inputs and four outputs to assess 681 facilities. These samples selected from the biggest demonstration area are the most representative for and exceed 2/5 of the running facilities all over the country. The average efficiency score of samples was 0.496 meaning the improvement potential was about 50.4%. Only 27 samples were relatively effective, scoring 1. The remaining 654 facilities had different levels of input excesses or output shortfalls, which should be the key objects to improve overall performance. In addition, there was evidence that output indicators had more room for improvement than input indicators. The analysis of sensitivity on inputs and outputs confirmed that the idleness and poor treatment effects of rural sewage treatment facilities should be concerned. Finally, Kruskal–Wallis non-parametric test verified that technology and load rate of facilities have significant impacts on efficiency. The performance evaluation results could not only provide guidance for the local government to strengthen the supervision and operation of facilities, but also potentially provide reference for the construction, operation and management of rural sewage treatment facilities in China

Distribution of Spectral Lags in Gamma Ray Bursts

Using the data acquired in the Time To Spill (TTS) mode for long gamma-ray bursts (GRBs) collected by the Burst and Transient Source Experiment on board the Compton Gamma Ray Observatory (BATSE/CGRO), we have carefully measured spectral lags in time between the low (25-55 keV) and high (110-320 keV) energy bands of individual pulses contained in 64 multi-peak GRBs. We find that the temporal lead by higher-energy gamma-ray photons (i.e., positive lags) is the norm in this selected sample set of long GRBs. While relatively few in number, some pulses of several long GRBs do show negative lags. This distribution of spectral lags in long GRBs is in contrast to that in short GRBs. This apparent difference poses challenges and constraints on the physical mechanism(s) of producing long and short GRBs. The relation between the pulse peak count rates and the spectral lags is also examined. Observationally, there seems to be no clear evidence for systematic spectral lag-luminosity connection for pulses within a given long GRB.Comment: 20 pages, 4 figure

Sustainability efficiency assessment of wastewater treatment plants in China: A data envelopment analysis based on cluster benchmarking

Quantitative evaluation on the efficiency of wastewater treatment plants (WWTPs) is a key issue that needs to be solved. For this purpose, data envelopment analysis (DEA) was employed to establish a comprehensive efficiency evaluation system on WWTPs, including three inputs of operating cost, electricity consumption and labor, three desirable outputs of chemical oxygen demand (COD) removal rate, ammonia nitrogen (NH3–N) removal rate and reclaimed water yield, and one undesirable output of dry sludge yield. 861 WWTPs in China were assessed by a slacked-based DEA model based on cluster benchmarking. The technology gap ratio (TGR) confirmed that large WWTPs operated more efficiently than small ones. The WWTPs had an average efficiency score of 0.611. Among them, 170 samples were relatively efficient with a score of 1, which means these samples could be a benchmark for other inefficient samples. Different degrees of input excesses or output shortfalls existed in 691 inefficient samples and these samples should be the key objects to improve the operational efficiency. Furthermore, through the Kruskal-Wallis test, the influent COD concentration and capacity load rate showed significant effects on the WWTP performance. These findings, derived from a simple but effective framework, have potential value for managers to make decisions

Regulation of Proapoptotic Mammalian ste20–Like Kinase MST2 by the IGF1-Akt Pathway

Hippo, a Drosophila serine/threonine kinase, promotes apoptosis and restricts cell growth and proliferation. Its mammalian homolog MST2 has been shown to play similar role and be regulated by Raf-1 via a kinase-independent mechanism and by RASSF family proteins through forming complex with MST2. However, regulation of MST2 by cell survival signal remains largely unknown.Using immunoblotting, in vitro kinase and in vivo labeling assays, we show that IGF1 inhibits MST2 cleavage and activation induced by DNA damage through the phosphatidylinosotol 3-kinase (PI3K)/Akt pathway. Akt phosphorylates a highly conserved threonine-117 residue of MST2 in vitro and in vivo, which leads to inhibition of MST2 cleavage, nuclear translocation, autophosphorylation-Thr180 and kinase activity. As a result, MST2 proapoptotic and growth arrest function was significantly reduced. Further, inverse correlation between pMST2-T117/pAkt and pMST2-T180 was observed in human breast tumors.Our findings demonstrate for the first time that extracellular cell survival signal IGF1 regulates MST2 and that Akt is a key upstream regulator of MST2

Inverse Spin Hall Effect and Anomalous Hall Effect in a Two-Dimensional Electron Gas

We study the coupled dynamics of spin and charge currents in a two-dimensional electron gas in the transport diffusive regime. For systems with inversion symmetry there are established relations between the spin Hall effect, the anomalous Hall effect and the inverse spin Hall effect. However, in two-dimensional electron gases of semiconductors like GaAs, inversion symmetry is broken so that the standard arguments do not apply. We demonstrate that in the presence of a Rashba type of spin-orbit coupling (broken structural inversion symmetry) the anomalous Hall effect, the spin Hall and inverse spin Hall effect are substantially different effects. Furthermore we discuss the inverse spin Hall effect for a two-dimensional electron gas with Rashba and Dresselhaus spin-orbit coupling; our results agree with a recent experiment.Comment: 5 page

The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA

Constitutive activation of pro-survival kinases has become a promising target of small molecules with an increasing interest in developing multi-targeted agents. The mechanisms underlying the responsiveness to most agents targeting cancer specific survival pathways are still poorly understood but critical for their clinical application. In this study, we found that sunitinib, a small molecule inhibitor of multiple tyrosine kinases including VEGFRs and PDGFRs induces apoptosis and inhibits cell growth in colon cancer cells in cell culture and xenograft models via the BH3-only protein PUMA. Sunitinib treatment induced PUMA transcription via the AKT/FoxO3a axis. PUMA, BH3 mimetics, or 5-Flurourical sensitized colon cancer cells to sunitinib-induced apoptosis. Furthermore, PUMA was induced by sunitinib treatment in xenograft tumors, and deficiency in PUMA significantly suppressed the anti-tumor effects of sunitinib. Our study suggests that PUMA-mediated apoptosis is important for the therapeutic responses to sunitinib, and activation of the mitochondrial pathway by BH3 mimetics or PUMA manipulation may be useful for improving the antitumor activity of sunitinib. Modulation of PUMA and selective Bcl-2 family members might be potential biomarkers for predicting sunitinib responses. © 2012 Sun et al