Design procedure for low-drag subsonic airfoils

Airfoil has least amount of drag under given restrictions of boundary layer transition position, lift coefficient, thickness ratio, and Reynolds number based on airfoil chord. It is suitable for use as wing and propeller aircraft sections operating at subsonic speeds and for hydrofoil sections and blades for fans, compressors, turbines, and windmills

Marginally Trapped Surfaces in the Nonsymmetric Gravitational Theory

We consider a simple, physical approach to the problem of marginally trapped surfaces in the Nonsymmetric Gravitational Theory (NGT). We apply this approach to a particular spherically symmetric, Wyman sector gravitational field, consisting of a pulse in the antisymmetric field variable. We demonstrate that marginally trapped surfaces do exist for this choice of initial data.Comment: REVTeX 3.0 with epsf macros and AMS symbols, 3 pages, 1 figur

Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2 and cell proliferation via Gαq-mediated mechanism

Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling. Emerging data suggest that the cardiovascular system is the main target of apelin, which exerts an overall neuroprotective role, and is a positive regulator of angiotensin-converting enzyme 2 (ACE2) in heart failure. Moreover, ACE2 cleaves off C-terminal residues of vasoactive peptides including apelin-13, and neurotensin that activate the apelin receptor (APJ) and neurotensin receptor 1 (NTSR1) respectively, that belong to the A class of GPCRs. Therefore, based on the similar mode of modification by ACE2 at peptide level, the homology at amino acid level and the capability of forming dimers with other GPCRs, we have been suggested that APJ and NTSR1 can form a functional heterodimer. Using co-immunoprecipitation, BRET and FRET, we provided conclusive evidence of heterodimerization between APJ and NTSR1 in a constitutive and induced form. Upon agonist stimulation, hetrodimerization enhanced ERK1/2 activation and increased proliferation via activation of Gq α-subunits. These novel data provide evidence for a physiological role of APJ/NTSR1 heterodimers in terms of ERK1/2 activation and increased intracellular calcium and induced cell proliferation and provide potential new pharmaceutical targets for cardiovascular disease. © 2014 The Authors

Waveguide cooling system

An improved system is described for cooling high power waveguides by the use of cooling ducts extending along the waveguide, which minimizes hot spots at the flanges where waveguide sections are connected together. The cooling duct extends along substantially the full length of the waveguide section, and each flange at the end of the section has a through hole with an inner end connected to the duct and an opposite end that can be aligned with a flange hole in another waveguide section. Earth flange is formed with a drainage groove in its face, between the through hole and the waveguide conduit to prevent leakage of cooling fluid into the waveguide. The ducts have narrowed sections immediately adjacent to the flanges to provide room for the installation of fasteners closely around the waveguide channel

Consistency of Markov chain quasi-Monte Carlo on continuous state spaces

The random numbers driving Markov chain Monte Carlo (MCMC) simulation are usually modeled as independent U(0,1) random variables. Tribble [Markov chain Monte Carlo algorithms using completely uniformly distributed driving sequences (2007) Stanford Univ.] reports substantial improvements when those random numbers are replaced by carefully balanced inputs from completely uniformly distributed sequences. The previous theoretical justification for using anything other than i.i.d. U(0,1) points shows consistency for estimated means, but only applies for discrete stationary distributions. We extend those results to some MCMC algorithms for continuous stationary distributions. The main motivation is the search for quasi-Monte Carlo versions of MCMC. As a side benefit, the results also establish consistency for the usual method of using pseudo-random numbers in place of random ones.Comment: Published in at http://dx.doi.org/10.1214/10-AOS831 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

Tri-Dirac Surface Modes in Topological Superconductors

We propose a new type of topological surface modes having cubic dispersion in three-dimensional topological superconductors. Lower order dispersions are prohibited by the threefold rotational symmetry and time-reversal symmetry. Cooper pairing in the bulk changes sign under improper rotations, akin to$^{3}$He-B. The surface manifestations are a divergent surface density of states at the Fermi level and isospins that rotate three times as they circle the origin in momentum space. We propose that Heusler alloys with band inversion are candidate materials to harbor the novel topological superconductivity.Comment: Five-page main text plus five-page supplementary materials; three figure