1,448 research outputs found
Author Correction: Systematic evaluation of 2′-Fluoro modified chimeric antisense oligonucleotide-mediated exon skipping in vitro
Correction to: Scientific Reports https://doi.org/10.1038/s41598-019-42523-0, published online 15 April 201
Non-structural mitigation programs for sediment-related disasters after the Chichi Earthquake in Taiwan
Following the Chichi Earthquake (M(L)=7.3) in 1999, sediment-related disasters, such as landslides and debris flows, have become more frequent in Taiwan. Because engineering structures cannot be fully and rapidly emplaced, the government has initiated non-structural hazard mitigation programs. Initially, community debris flow evacuation drills were promoted in 2000. Typhoon Toraji caused numerous debris flow events in July 2001, and some communities evacuated according to the drills, significantly reducing the numbers of possible casualties. Based on that result, the government expanded the program for evacuation drills. Secondly, the early warning system created after the Chichi Earthquake will prevent many potential future casualties. Rainfall threshold values for debris flow warnings in different areas are determined from information received from local weather stations and modified for local geomorphologic situations. Realtime information is gradually being integrated to create a debris flow disaster warning system, the goal of which is to provide warnings to zones in which debris flows are likely. The warning system was launched in 2005 and has two levels of alarms: yellow and red. The final, red alarm triggers enforced evacuation. Overall, the decrease in casualties from debris flows during the decade after the Chichi Earthquake is not the result of a decrease in number or severity of sediment related disasters, but is more directly related to the gradually improved early warning and evacuation system. However, the compound hazards resulting from Typhoon Morakot in 2009 remind us of the ongoing need for improving the existing mitigation system
Inhibitory effect of rhubarb on intestinal α-glucosidase activity in type 1 diabetic rats
Purpose: To investigate the inhibitory effect of rhubarb on α-glucosidase activity in the small intestine of rats with type 1 diabetes.Methods: Type 1 diabetic rat model was established by intraperitoneally injecting 30 male SD rats with 1 % streptozocin (STZ). Rats with fasting blood glucose > 11 mmol/L (24) were used for the study. The rats were randomly divided into three equal groups including control, acarbose and rhubarb groups. Arcabose® (20 mg/kg /day) and rhubarb (100 mg/kg /day) were given by intra-gastric route via insertion of the cannula through the esophagus. Daily fasting blood glucose and daily postprandial glucose levels were assayed for all groups. On day 6, postprandial blood glucose, blood levels of C-peptide and insulin, and intestinal α-glucosidase were also determined.Results: There were no significant differences in levels of C-peptide, insulin and fasting blood glucose between control, Acarbose® and rhubarb groups (p > 0.05). However, α-glucosidase activity at 0, 30, 60 and 120 min in the rhubarb group was 1759.2, 1812.8, 1379.8 and 772.1 U, respectively,) while in the Acarbose® group it was 178.6, 1260.1, 1126.5, 599.2 U, respectively. α-Glucosidase activity in both groups initially showed an increase (p < 0.05), followed by a decline from 60 to 120 min (p ˂ 0.05). After 120 min, α-glucosidase activity in each of the two groups was significantly decreased compared with untreated control (1200 U) (p ˂ 0.05).Conclusion: The inhibitory effect of rhubarb on intestinal α-glucosidase activity of Type 1 diabetic rats is comparable to that of Arcabose®.This suggests that this plant may have clinically potent anti-diabetic properties.Keywords: Type 1 diabetes, α-Glucosidase activity, Acarbose®, Rhubarb, Postprandial glucose leve
Four methods for determining the composition of trace radioactive surface contamination of low-radioactivity metal
Four methods for determining the composition of low-level uranium- and
thorium-chain surface contamination are presented. One method is the
observation of Cherenkov light production in water. In two additional methods a
position-sensitive proportional counter surrounding the surface is used to make
both a measurement of the energy spectrum of alpha particle emissions and also
coincidence measurements to derive the thorium-chain content based on the
presence of short-lived isotopes in that decay chain. The fourth method is a
radiochemical technique in which the surface is eluted with a weak acid, the
eluate is concentrated, added to liquid scintillator and assayed by recording
beta-alpha coincidences. These methods were used to characterize two `hotspots'
on the outer surface of one of the He-3 proportional counters in the Neutral
Current Detection array of the Sudbury Neutrino Observatory experiment. The
methods have similar sensitivities, of order tens of ng, to both thorium- and
uranium-chain contamination.Comment: 22 pages, 19 figure
Constraints on Neutrino Parameters from Neutral-Current Solar Neutrino Measurements
We generalize the pull approach to define the function to the
analysis of the data with correlated statistical errors. We apply this method
to the analysis of the Sudbury Neutrino Collaboration data obtained in the
salt-phase. In the global analysis of all the solar neutrino and KamLAND data
we find the best fit (minimum ) values of neutrino parameters to be
and
eV. We confirm that the maximal mixing is strongly disfavored while the
bounds on are significantly strengthened.Comment: 6 figures. Some typos are corrected, figures are visually improve
Magnetism in systems with various dimensionality: A comparison between Fe and Co
A systematic ab initio study is performed for the spin and orbital moments
and for the validity of the sum rules for x-ray magnetic circular dichroism for
Fe systems with various dimensionality (bulk, Pt-supported monolayers and
monatomic wires, free-standing monolayers and monatomic wires). Qualitatively,
the results are similar to those for the respective Co systems, with the main
difference that for the monatomic Fe wires the term in the spin sum rule
is much larger than for the Co wires. The spin and orbital moments induced in
the Pt substrate are also discussed.Comment: 4 page
Magnetic versus crystal field linear dichroism in NiO thin films
We have detected strong dichroism in the Ni x-ray absorption
spectra of monolayer NiO films. The dichroic signal appears to be very similar
to the magnetic linear dichroism observed for thicker antiferromagnetic NiO
films. A detailed experimental and theoretical analysis reveals, however, that
the dichroism is caused by crystal field effects in the monolayer films, which
is a non trivial effect because the high spin Ni ground state is not
split by low symmetry crystal fields. We present a practical experimental
method for identifying the independent magnetic and crystal field contributions
to the linear dichroic signal in spectra of NiO films with arbitrary
thicknesses and lattice strains. Our findings are also directly relevant for
high spin and systems such as LaFeO, FeO,
VO, LaCrO, CrO, and Mn manganate thin films
X-Ray Magnetic Circular Dichroism at the K edge of Mn3GaC
We theoretically investigate the origin of the x-ray magnetic circular
dichroism (XMCD) spectra at the K edges of Mn and Ga in the ferromagnetic phase
of Mn3GaC on the basis of an ab initio calculation. Taking account of the
spin-orbit interaction in the LDA scheme, we obtain the XMCD spectra in
excellent agreement with the recent experiment. We have analyzed the origin of
each structure, and thus elucidated the mechanism of inducing the orbital
polarization in the p symmetric states. We also discuss a simple sum rule
connecting the XMCD spectra with the orbital moment in the p symmetric states.Comment: 5 pages, 5 figures, accepted for publication in Physical Review
Multiwavelength Study on Solar and Interplanetary Origins of the Strongest Geomagnetic Storm of Solar Cycle 23
We study the solar sources of an intense geomagnetic storm of solar cycle 23
that occurred on 20 November 2003, based on ground- and space-based
multiwavelength observations. The coronal mass ejections (CMEs) responsible for
the above geomagnetic storm originated from the super-active region NOAA 10501.
We investigate the H-alpha observations of the flare events made with a 15 cm
solar tower telescope at ARIES, Nainital, India. The propagation
characteristics of the CMEs have been derived from the three-dimensional images
of the solar wind (i.e., density and speed) obtained from the interplanetary
scintillation data, supplemented with other ground- and space-based
measurements. The TRACE, SXI and H-alpha observations revealed two successive
ejections (of speeds ~350 and ~100 km/s), originating from the same filament
channel, which were associated with two high speed CMEs (~1223 and ~1660 km/s,
respectively). These two ejections generated propagating fast shock waves
(i.e., fast drifting type II radio bursts) in the corona. The interaction of
these CMEs along the Sun-Earth line has led to the severity of the storm.
According to our investigation, the interplanetary medium consisted of two
merging magnetic clouds (MCs) that preserved their identity during their
propagation. These magnetic clouds made the interplanetary magnetic field (IMF)
southward for a long time, which reconnected with the geomagnetic field,
resulting the super-storm (Dst_peak=-472 nT) on the Earth.Comment: 24 pages, 16 figures, Accepted for publication in Solar Physic
Nanosized superparamagnetic precipitates in cobalt-doped ZnO
The existence of semiconductors exhibiting long-range ferromagnetic ordering
at room temperature still is controversial. One particularly important issue is
the presence of secondary magnetic phases such as clusters, segregations,
etc... These are often tedious to detect, leading to contradictory
interpretations. We show that in our cobalt doped ZnO films grown
homoepitaxially on single crystalline ZnO substrates the magnetism
unambiguously stems from metallic cobalt nano-inclusions. The magnetic behavior
was investigated by SQUID magnetometry, x-ray magnetic circular dichroism, and
AC susceptibility measurements. The results were correlated to a detailed
microstructural analysis based on high resolution x-ray diffraction,
transmission electron microscopy, and electron-spectroscopic imaging. No
evidence for carrier mediated ferromagnetic exchange between diluted cobalt
moments was found. In contrast, the combined data provide clear evidence that
the observed room temperature ferromagnetic-like behavior originates from
nanometer sized superparamagnetic metallic cobalt precipitates.Comment: 20 pages, 6 figures; details about background subtraction added to
section III. (XMCD
- …