Entanglement can completely defeat quantum noise

We describe two quantum channels that individually cannot send any information, even classical, without some chance of decoding error. But together a single use of each channel can send quantum information perfectly reliably. This proves that the zero-error classical capacity exhibits superactivation, the extreme form of the superadditivity phenomenon in which entangled inputs allow communication over zero capacity channels. But our result is stronger still, as it even allows zero-error quantum communication when the two channels are combined. Thus our result shows a new remarkable way in which entanglement across two systems can be used to resist noise, in this case perfectly. We also show a new form of superactivation by entanglement shared between sender and receiver.Comment: 4 pages, 1 figur

Potentially Inappropriate Prescribing of Proton Pump Inhibitors Among Older Patients in the US

The American Geriatrics Society list of Potentially Inappropriate Medication (Beers Criteria) use in older adults (\u3e64-years) includes Proton Pump Inhibitors (PPIs), and specifically cautions against their use for \u3e8 weeks. PPIs are prescribed to reduce the production of stomach acid, however there is strong evidence older adults are at risk of infection and bone loss from prolonged exposure to PPIs. This study used data from the 2017 Medical Expenditure Panel Survey (MEPS) and the FDA Adverse Event Report System (FAERS, as of June 30, 2019) to characterize the current prescribing practices of PPIs to older adults and the risks those patients may face. 4,288 patients \u3e64-years were included in this study, weighted to represent over 46 million Americans. Of these, 19.6% had been prescribed a PPI in 2017, and 10.05% had a long-term (\u3e8 week) prescription. Results from a generalized linear model using a quasibinomial link function demonstrated that patients with arthritis (adjusted-OR: 1.52, 95% CI: 1.17-1.98) and asthma (adjusted-OR: 1.73, 95% CI: 1.24-2.41) were more likely to have long-term PPI use, as were patients with 5+ other prescriptions (adjusted-OR: 4.31, 95% CI: 2.71-6.85). The adjusted odds ratios (OR) did not differ by age, gender, income, or education-level. For all PPIs, 28,031 (age\u3e64) adverse event (AE) cases were found in FAERS. The most commonly reported AEs were gastrointestinal disorders, and renal or urinary disorders, which appeared in 50% of included cases. Overall, our study reported current risks from and potential predictors of long-term PPI use among older adults

Invariant information and complementarity in high-dimensional states

Using a generalization of the invariant information introduced by Brukner and Zeilinger [Phys. Rev. Lett. \textbf{83}, 3354 (1999)] to high-dimensional systems, we introduce a complementarity relation between the local and nonlocal information for $d\times d$ systems under the isolated environment, where $d$ is prime or the power of prime. We also analyze the dynamics of the local information in the decoherence process.Comment: 4 pages, 2 figure

Archiving and Delivery of 3DTI Rehabilitation Sessions

In this paper we present CyPhy: a cyber-physiotherapy system that brings daily rehabilitation to patient’s home with supervision from trained therapist. With its archiving and delivery features, CyPhy is able to 1) capture and record RGB-D and physiotherapy-related medical sensing data streams in home environment; 2) provide efficient storage for rehabilitation session recordings; 3) provide fast metadata analysis over stored sessions for review recommendation; 4) adaptively deliver rehabilitation session under different networking capabilities; 5) support smooth viewpoint changing during 3D video streaming with scene rendering schemes tailored for devices with different bandwidth and power limitations; and 6) provide platform-independent streaming client for various mobile and PC environments

On Coding for Reliable Communication over Packet Networks

We present a capacity-achieving coding scheme for unicast or multicast over lossy packet networks. In the scheme, intermediate nodes perform additional coding yet do not decode nor even wait for a block of packets before sending out coded packets. Rather, whenever they have a transmission opportunity, they send out coded packets formed from random linear combinations of previously received packets. All coding and decoding operations have polynomial complexity. We show that the scheme is capacity-achieving as long as packets received on a link arrive according to a process that has an average rate. Thus, packet losses on a link may exhibit correlation in time or with losses on other links. In the special case of Poisson traffic with i.i.d. losses, we give error exponents that quantify the rate of decay of the probability of error with coding delay. Our analysis of the scheme shows that it is not only capacity-achieving, but that the propagation of packets carrying "innovative" information follows the propagation of jobs through a queueing network, and therefore fluid flow models yield good approximations. We consider networks with both lossy point-to-point and broadcast links, allowing us to model both wireline and wireless packet networks.Comment: 33 pages, 6 figures; revised appendi

Entropic uncertainty relations and entanglement

We discuss the relationship between entropic uncertainty relations and entanglement. We present two methods for deriving separability criteria in terms of entropic uncertainty relations. Especially we show how any entropic uncertainty relation on one part of the system results in a separability condition on the composite system. We investigate the resulting criteria using the Tsallis entropy for two and three qubits.Comment: 8 pages, 3 figures, v2: small change

Determinants of a transcriptionally competent environment at the GM-CSF promoter

Granulocyte macrophage-colony stimulating factor (GM-CSF) is produced by T cells, but not B cells, in response to immune signals. GM-CSF gene activation in response to T-cell stimulation requires remodelling of chromatin associated with the gene promoter, and these changes do not occur in B cells. While the CpG methylation status of the murine GM-CSF promoter shows no correlation with the ability of the gene to respond to activation, we find that the basal chromatin environment of the gene promoter influences its ability to respond to immune signals. In unstimulated T cells but not B cells, the GM-CSF promoter is selectively marked by enrichment of histone acetylation, and association of the chromatin-remodelling protein BRG1. BRG1 is removed from the promoter upon activation concomitant with histone depletion and BRG1 is required for efficient chromatin remodelling and transcription. Increasing histone acetylation at the promoter in T cells is paralleled by increased BRG1 recruitment, resulting in more rapid chromatin remodelling, and an associated increase in GM-CSF mRNA levels. Furthermore, increasing histone acetylation in B cells removes the block in chromatin remodelling and transcriptional activation of the GM-CSF gene. These data are consistent with a model in which histone hyperacetylation and BRG1 enrichment at the GM-CSF promoter, generate a chromatin environment competent to respond to immune signals resulting in gene activation

Defining the chromatin signature of inducible genes in T cells

BACKGROUND Specific chromatin characteristics, especially the modification status of the core histone proteins, are associated with active and inactive genes. There is growing evidence that genes that respond to environmental or developmental signals may possess distinct chromatin marks. Using a T cell model and both genome-wide and gene-focused approaches, we examined the chromatin characteristics of genes that respond to T cell activation. RESULTS To facilitate comparison of genes with similar basal expression levels, we used expression-profiling data to bin genes according to their basal expression levels. We found that inducible genes in the lower basal expression bins, especially rapidly induced primary response genes, were more likely than their non-responsive counterparts to display the histone modifications of active genes, have RNA polymerase II (Pol II) at their promoters and show evidence of ongoing basal elongation. There was little or no evidence for the presence of active chromatin marks in the absence of promoter Pol II on these inducible genes. In addition, we identified a subgroup of genes with active promoter chromatin marks and promoter Pol II but no evidence of elongation. Following T cell activation, we find little evidence for a major shift in the active chromatin signature around inducible gene promoters but many genes recruit more Pol II and show increased evidence of elongation. CONCLUSIONS These results suggest that the majority of inducible genes are primed for activation by having an active chromatin signature and promoter Pol II with or without ongoing elongation

Divergence and Shannon information in genomes

Shannon information (SI) and its special case, divergence, are defined for a DNA sequence in terms of probabilities of chemical words in the sequence and are computed for a set of complete genomes highly diverse in length and composition. We find the following: SI (but not divergence) is inversely proportional to sequence length for a random sequence but is length-independent for genomes; the genomic SI is always greater and, for shorter words and longer sequences, hundreds to thousands times greater than the SI in a random sequence whose length and composition match those of the genome; genomic SIs appear to have word-length dependent universal values. The universality is inferred to be an evolution footprint of a universal mode for genome growth.Comment: 4 pages, 3 tables, 2 figure