2,061 research outputs found

    PMS16 Economic Evidence of Biologics in Rheumatoid Arthritis: A Systematic Review for Supporting Informed Decision of BNHI

    Get PDF

    Schramm-Loewner Equations Driven by Symmetric Stable Processes

    Full text link
    We consider shape, size and regularity of the hulls of the chordal Schramm-Loewner evolution driven by a symmetric alpha-stable process. We obtain derivative estimates, show that the complements of the hulls are Hoelder domains, prove that the hulls have Hausdorff dimension 1, and show that the trace is right-continuous with left limits almost surely.Comment: 22 pages, 4 figure

    Stationary distributions for diffusions with inert drift

    Get PDF
    Consider reflecting Brownian motion in a bounded domain in Rd{\mathbb R^d} that acquires drift in proportion to the amount of local time spent on the boundary of the domain. We show that the stationary distribution for the joint law of the position of the reflecting Brownian motion and the value of the drift vector has a product form. Moreover, the first component is uniformly distributed on the domain, and the second component has a Gaussian distribution. We also consider more general reflecting diffusions with inert drift as well as processes where the drift is given in terms of the gradient of a potential

    Self-intersection local times of random walks: Exponential moments in subcritical dimensions

    Get PDF
    Fix p>1p>1, not necessarily integer, with p(d2)<dp(d-2)<d. We study the pp-fold self-intersection local time of a simple random walk on the lattice Zd\Z^d up to time tt. This is the pp-norm of the vector of the walker's local times, t\ell_t. We derive precise logarithmic asymptotics of the expectation of exp{θttp}\exp\{\theta_t \|\ell_t\|_p\} for scales θt>0\theta_t>0 that are bounded from above, possibly tending to zero. The speed is identified in terms of mixed powers of tt and θt\theta_t, and the precise rate is characterized in terms of a variational formula, which is in close connection to the {\it Gagliardo-Nirenberg inequality}. As a corollary, we obtain a large-deviation principle for tp/(trt)\|\ell_t\|_p/(t r_t) for deviation functions rtr_t satisfying t r_t\gg\E[\|\ell_t\|_p]. Informally, it turns out that the random walk homogeneously squeezes in a tt-dependent box with diameter of order t1/d\ll t^{1/d} to produce the required amount of self-intersections. Our main tool is an upper bound for the joint density of the local times of the walk.Comment: 15 pages. To appear in Probability Theory and Related Fields. The final publication is available at springerlink.co

    Stellar adiabatic mass loss model and applications

    Full text link
    Roche-lobe overflow and common envelope evolution are very important in binary evolution, which is believed to be the main evolutionary channel to hot subdwarf stars. The details of these processes are difficult to model, but adiabatic expansion provides an excellent approximation to the structure of a donor star undergoing dynamical time scale mass transfer. We can use this model to study the responses of stars of various masses and evolutionary stages as potential donor stars, with the urgent goal of obtaining more accurate stability criteria for dynamical mass transfer in binary population synthesis studies. As examples, we describe here several models with the initial masses equal to 1 Msun and 10 Msun, and identify potential limitations to the use of our results for giant-branch stars.Comment: 7 pages, 5 figures,Accepted for publication in AP&SS, Special issue Hot Sub-dwarf Stars, in Han Z., Jeffery S., Podsiadlowski Ph. ed

    ECC2K-130 on NVIDIA GPUs

    Get PDF
    A major cryptanalytic computation is currently underway on multiple platforms, including standard CPUs, FPGAs, PlayStations and Graphics Processing Units (GPUs), to break the Certicom ECC2K-130 challenge. This challenge is to compute an elliptic-curve discrete logarithm on a Koblitz curve over F2131\rm F_{2^{131}} . Optimizations have reduced the cost of the computation to approximately 277 bit operations in 261 iterations. GPUs are not designed for fast binary-field arithmetic; they are designed for highly vectorizable floating-point computations that fit into very small amounts of static RAM. This paper explains how to optimize the ECC2K-130 computation for this unusual platform. The resulting GPU software performs more than 63 million iterations per second, including 320 million F2131\rm F_{2^{131}} multiplications per second, on a $500 NVIDIA GTX 295 graphics card. The same techniques for finite-field arithmetic and elliptic-curve arithmetic can be reused in implementations of larger systems that are secure against similar attacks, making GPUs an interesting option as coprocessors when a busy Internet server has many elliptic-curve operations to perform in parallel

    The pseudogap state in superconductors: Extended Hartree approach to time-dependent Ginzburg-Landau Theory

    Full text link
    It is well known that conventional pairing fluctuation theory at the Hartree level leads to a normal state pseudogap in the fermionic spectrum. Our goal is to extend this Hartree approximated scheme to arrive at a generalized mean field theory of pseudogapped superconductors for all temperatures TT. While an equivalent approach to the pseudogap has been derived elsewhere using a more formal Green's function decoupling scheme, in this paper we re-interpret this mean field theory and BCS theory as well, and demonstrate how they naturally relate to ideal Bose gas condensation. Here we recast the Hartree approximated Ginzburg-Landau self consistent equations in a T-matrix form. This recasting makes it possible to consider arbitrarily strong attractive coupling, where bosonic degrees of freedom appear at T T^* considerably above TcT_c. The implications for transport both above and below TcT_c are discussed. Below TcT_c we find two types of contributions. Those associated with fermionic excitations have the usual BCS functional form. That they depend on the magnitude of the excitation gap, nevertheless, leads to rather atypical transport properties in the strong coupling limit, where this gap (as distinct from the order parameter) is virtually TT-independent. In addition, there are bosonic terms arising from non-condensed pairs whose transport properties are shown here to be reasonably well described by an effective time-dependent Ginzburg-Landau theory.Comment: 14 pages, 5 figures, REVTeX4, submitted to PRB; clarification of the diagrammatic technique added, one figure update

    Test for entanglement using physically observable witness operators and positive maps

    Full text link
    Motivated by the Peres-Horodecki criterion and the realignment criterion we develop a more powerful method to identify entangled states for any bipartite system through a universal construction of the witness operator. The method also gives a new family of positive but non-completely positive maps of arbitrary high dimensions which provide a much better test than the witness operators themselves. Moreover, we find there are two types of positive maps that can detect 2xN and 4xN bound entangled states. Since entanglement witnesses are physical observables and may be measured locally our construction could be of great significance for future experiments.Comment: 6 pages, 1 figure, revtex4 styl

    Nucleon electroweak form factors in a meson-cloud model

    Get PDF
    The meson-cloud model of the nucleon consisting of a system of three valence quarks surrounded by a meson cloud is applied to study the electroweak structure of the proton and neutron. The electroweak nucleon form factors are calculated within a light-front approach, by obtaining an overall good description of the experimental data. Charge densities as a function of the transverse distance with respect to the direction of the three-momentum transfer are also discussed.Comment: Prepared for Proceedings of NSTAR2007, Workshop on the physics of excited nucleons, Bonn (Germany), 5-8 September 200

    The fermion dynamical symmetry model for the even--even and even--odd nuclei in the Xe--Ba region

    Full text link
    The even--even and even--odd nuclei 126^{126}Xe-132^{132}Xe and 131^{131}Ba-137^{137}Ba are shown to have a well-realized SO8SO6SO3SO_8 \supset SO_6 \supset SO_3 fermion dynamical symmetry. Their low-lying energy levels can be described by a unified analytical expression with two (three) adjustable parameters for even--odd (even--even) nuclei that is derived from the fermion dynamical symmetry model. Analytical expressions are given for wavefunctions and for E2E2 transition rates that agree well with data. The distinction between the FDSM and IBM SO6SO_6 limits is discussed. The experimentally observed suppression of the the energy levels with increasing SO5SO_5 quantum number τ\tau can be explained as a perturbation of the pairing interaction on the SO6SO_6 symmetry, which leads to an SO5SO_5 Pairing effect for SO6SO_6 nuclei.Comment: submitted to Phys. Rev. C, LaTeX, 31 pages, 8 figures with postscript files available on request at [email protected]
    corecore