EVALUATION OF THE EFFICACY OF PRANAYAMA ON THE LUNGS

Yoga is a science which has been practised in India from over thousands of years. Besides the spiritual achievements, the practice of yoga is accompanied by a number of beneficial physiological effects in the body. Yoga and health goes hand in hand. Yoga calms and relaxes the mind and it strengthens and tunes the body and brings them into harmony with each another. Pranayama is an art of controlling the life force of breath [1]. It produces many systemic psycho-physical effects in the body, besides its specific effects on the respiratory functions. This study is designed to study the effects of pranayama (12 weeks) on the pulmonary function parameters. It is one of the best lifestyle modifications which have ever been devised in the history of mankind. There are many classical paths which have been described to reach the ultimate goal of healthy life. It is an ancient yoga technique, a spiritual and physical practice which integrates the mind and body. Pranayama is a type of yogic practice which produces many systemic psycho-physical effects in the body, besides its specific effects on the respiratory functions. So, it has become a standard fare at health clubs and community recreation programmes.Pulmonary function tests (PFTs) are simple screening procedures which are performed by using a standardized equipment (spirometer) to measure the lung function. This test provides useful information about the minimum levels of the lung function. The breath holding time measures the level of the threshold of the respiratory center to the partial pressure of the carbon dioxide (Pco2) level.Pulmonary function tests have been studied in yoga and pranayama practitioners. They have shown that the regular practice of these pranayama techniques have proved to be beneficial for the human body. Pranayama has a favourable influence and it causes a marked improvement in the lung functions. This study is designed to study the effects of pranayama (12 weeks) on the pulmonary function parameters.In these clinical trial 60 patients of mild to moderate hypertensive patients were randomly selected and divided in to two groups. In each group 30 patients had taken. In Group A Pranayam had been given to the 30 patients of mild to moderate hypertensive patients and In Group B only placebo drug Prana had given to the 30 patients mild to moderate hypertensive patients. In all these two groups, group A was found as the most benefited because it showed significant changes in symptoms and Biochemistry investigations. Whereas in Group B (Placebo group) showed insignificant changes in symptoms as well as in Biochemistry investigations.    Key words-For Yoga- Pranayama, Yoga, Pulmonary Function Parameters FVC FEV1 FEF (25-75percent), and BHT For Hypertension-Vyan vikriti, vyan bala, Raktavritta vata, Raktagata vata, Dhamani Pratichaya, Siragata vata, Rasabhara, Dhamani Prapurnata, Vyanavrita vata etc. Â

COMPARATIVE STUDY OF THE SHIVA GUGGULU AND SIMHANADA GUGGULU IN THE MANAGEMENT OF AMAVATA (RHEUMATOID ARTHRITIS)

Objective: Comparison of effectiveness of two drugs (Shiva Guggulu and Simhanada Guggulu in the same dose of both drug given separately in two different groupA and Group B) on patients of Amavata. Methods: Patients between 18-60 y of age with classical features of Amavata [9] from OPD and IPD of Government autonomous Ayurvedic College and Hospital were selected for the present work; irrespective of their sex, religion, education, etc. Detailed research Performa was prepared to incorporate all the signs and symptoms of the disease Amavata is the second most common joint disorders. Nowadays erroneous dietary habits, lifestyle and environment have led to various autoimmune disorders i.e. Amavisajanya Vikaara and Amavata is one among them. Rheumatoid arthritis can be correlated with Amavata in view of its clinical features. Many research studies have been done to solve this clinical enigma, but an effective, safe, less complicated treatment is still required for the management of Amavata. In the present study, 24 patients of Amavata were registered and randomly grouped into two. In group A, Shiva Guggulu 6 g/day in divided doses and in group B, Simhanada Guggulu 6 g/day in divided doses were given for 8 w. On analysis of the results, it was found that Simhanada Guggulu provided better results as compared to Shiva Guggulu in the management of Amavata. In group A, the mean score of grip strength was 1.14 before treatment, which was reduced to 0.57 after treatment, with 50% relief. It was statistically insignificant. The mean score of grip strength in group B was 2.4 before treatment, which was reduced to 1.5 after treatment, with 37.5% relief. It was statistically highly significant. Results: Before treatment the mean score of walking time in group A was 2, which was reduced to 1 after treatment, with 50% relief. It was statistically insignificant. The mean score of walking time in group B was 1.75 before treatment, which was reduced to 0.75 after treatment, with 45.71% relief. It was statistically significant. In group A, the mean score of foot pressure was 1 before treatment, which was decreased to 0.66 after treatment, with 33.33% relief. It was statistically insignificant. The mean score of foot pressure in group B was 2.3 before treatment, which was decreased to 1.4 after treatment with, 39.13% relief. It was statistically highly significant. In group A, the mean score of general functional capacity was 1.33 before treatment, which was reduced to 0.66 after treatment, with 50% relief. It was statistically highly significant. The mean score of general functional capacity in group B was 1.66 before treatment, which was reduced to 0.66 after treatment, with 60% relief and was statistically insignificant. In group A, the mean score of the degree of disease activity was 1.75 before treatment, which was reduced to 1 after treatment, with 42.85% relief. It was statistically highly significant. The mean score of the degree of disease activity in group B was 1.5 before treatment, which was reduced to 0.75 after treatment, with 50% relief. It was statistically significant. Regarding ESR value, the mean scores before treatment in A and B groups were 54.5 and 55.2, respectively, and they were reduced to 45.3 and 40.1, respectively, after treatment. Group A percentage relief was 16.88%, while in group B it was 27.35%. An apparent difference in improvement of all the cardinal symptoms was observed with the treatment. On comparing Group B proved to be better than Group A. Statistically highly significant difference was found in the improvement of Sandhigraha and statistically significant difference was found in the improvement of Sandhishoola and Sparshasahyata by Simhanada Guggulu than Shiva Guggulu, whereas insignificant difference was observed in the improvement of Sandhishotha. So, from the obtained data it may be inferred that group B is more effective than groupA. Conclusion: It was observed from the treatment that Simhanada Guggulu provided comparatively better relief in cardinal signs and symptoms of Amavata. Keywords: Agni, Ama, Amavata, Rheumatoid arthritis, Shiva Guggulu, Simhanada Guggul

Discutindo a educação ambiental no cotidiano escolar: desenvolvimento de projetos na escola formação inicial e continuada de professores

A presente pesquisa buscou discutir como a Educação Ambiental (EA) vem sendo trabalhada, no Ensino Fundamental e como os docentes desta escola compreendem e vem inserindo a EA no cotidiano escolar., em uma escola estadual do município de Tangará da Serra/MT, Brasil. Para tanto, realizou-se entrevistas com os professores que fazem parte de um projeto interdisciplinar de EA na escola pesquisada. Verificou-se que o projeto da escola não vem conseguindo alcançar os objetivos propostos por: desconhecimento do mesmo, pelos professores; formação deficiente dos professores, não entendimento da EA como processo de ensino-aprendizagem, falta de recursos didáticos, planejamento inadequado das atividades. A partir dessa constatação, procurou-se debater a impossibilidade de tratar do tema fora do trabalho interdisciplinar, bem como, e principalmente, a importância de um estudo mais aprofundado de EA, vinculando teoria e prática, tanto na formação docente, como em projetos escolares, a fim de fugir do tradicional vínculo “EA e ecologia, lixo e horta”.Facultad de Humanidades y Ciencias de la Educació

EFFICACY OF AYURVEDIC DRUGS ON THE 150 PATIENTS OF DIABETIC NEPHROPATHY

It has been estimated that the global burden of type 2 diabetes mellitus (T2DM) for 2010 would be 285 million people (2010) which is projected to increase to 438 million in 2030; a 65 percent increase. Similarly, for India this increase is estimated to be 58percent, from 51 million people in 2010 to 87 million in 2030[1-2]. The impacts of T2DM are considerable: as a lifelong disease, it increases morbidity and mortality and decreases the quality of life [3]. At the same time, the disease and its complications cause a heavy economic burden for diabetic patients themselves, their families and society. A better understanding about the cause of a predisposition of Indians to get T2DM is necessary for future planning of healthcare, policy and delivery in order to ensure that the burdens of disease are addressed [4].This chapter on will focus on type T2DM and will provide a description of prevalence and incidence of T2DM in India; it will describe the health related complications, along with its various risk factors and recommended treatment. It will discuss current management practices and government policies for T2DM in India as well as identify policy and research gaps. Diabetes Morbidity and Mortality in India-Responsible for 109 thousand deaths in 2004 and 1.157 million years of life lost in 2004 [4-5] 2.263 million disability adjusted life years (DALYs) in India during 2004(ICMR 2006) Type 2 diabetes is an ever-growing problem worldwide. Approximately 40percent of the patients with type 2 diabetes will develop diabetic kidney disease. Diabetic nephropathy is a specific form of renal disease. It is a major cause of renal insufficiency and ultimately of death. The present study has been carried out to prove the efficacy of Ayurvedic drugs in the management of diabetic nephropathy, which can be helpful in reducing the need of dialysis and avoiding or delaying renal transplantation. Diabetic nephropathy is a specific form of renal complication of Diabetes Mellitus (DM), a major cause of death and disability among diabetics. It is observed that even the patients having well-controlled diabetes suffer from diabetic nephropathy. Diabetic nephropathy accounts for approximately 14percent of all deaths in diabetic patients, and some 25percent of those developing diabetes under the age of 30 die from renal failure due to diabetic nephropathy. [6] This is also a major cause of chronic renal failure as it accounts for 20-40percent patients of chronic renal failure. [7] A total of 150 patients of this disease were treated in IPD (Group A) and OPD (Group B) Nandlalpura Hospital and local regional area of lokmanya nagar under the guidance of Dr S.K.Das Adhikari. Ayurvedic formulations including Gokshuradi Guggulu, Bhumyamalaki, Punarnavastak Kwath, Vasa and Shilajatvadi Vati were given to all the patients for 3 months. Group A patients were given special planned food. Results were analyzed statistically using t†test. In group A patients, highly significant reduction was found in the values of serum creatinine, blood urea and urinary excretion of albumin. Marked improvement was found in the patients' general physical well-being, together with reduction in symptoms, in group A patients. This shows the importance of Pathyapathya in Ayurvedic management of the disease. This management may bring some new hope to the patients of diabetic nephropathy, which usually terminates to chronic renal failure and ultimately to death. Further studies are being carried out in this regard. The authors found some encouraging results in the patients of diabetic nephropathy with certain Ayurvedic treatments during clinical practice. These significantly correct albuminuria, which is the cardinal feature of diabetic nephropathy, and improve renal function which is evident by reduction in serum creatinine. In addition, the treatments also improve the general condition of the patient. Further studies are being carried out in this regard Keywords: Diabetic Nephropathy,Â

Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020

This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India. Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-

Health-status outcomes with invasive or conservative care in coronary disease

BACKGROUND In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients. METHODS We assessed angina-related symptoms, function, and quality of life with the Seattle Angina Questionnaire (SAQ) at randomization, at months 1.5, 3, and 6, and every 6 months thereafter in participants who had been randomly assigned to an invasive treatment strategy (2295 participants) or a conservative strategy (2322). Mixed-effects cumulative probability models within a Bayesian framework were used to estimate differences between the treatment groups. The primary outcome of this health-status analysis was the SAQ summary score (scores range from 0 to 100, with higher scores indicating better health status). All analyses were performed in the overall population and according to baseline angina frequency. RESULTS At baseline, 35% of patients reported having no angina in the previous month. SAQ summary scores increased in both treatment groups, with increases at 3, 12, and 36 months that were 4.1 points (95% credible interval, 3.2 to 5.0), 4.2 points (95% credible interval, 3.3 to 5.1), and 2.9 points (95% credible interval, 2.2 to 3.7) higher with the invasive strategy than with the conservative strategy. Differences were larger among participants who had more frequent angina at baseline (8.5 vs. 0.1 points at 3 months and 5.3 vs. 1.2 points at 36 months among participants with daily or weekly angina as compared with no angina). CONCLUSIONS In the overall trial population with moderate or severe ischemia, which included 35% of participants without angina at baseline, patients randomly assigned to the invasive strategy had greater improvement in angina-related health status than those assigned to the conservative strategy. The modest mean differences favoring the invasive strategy in the overall group reflected minimal differences among asymptomatic patients and larger differences among patients who had had angina at baseline

Initial invasive or conservative strategy for stable coronary disease

BACKGROUND Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, 121.8 percentage points; 95% CI, 124.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used