2,620 research outputs found

    Defects in the Compound Bi2te3 Caused by Irradiation with Protons

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    Defects in single crystals of bismuth telluride caused by proton irradiatio

    Test Experiment for Time-Reversal Symmetry Breaking Superconductivity

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    A new experiment is proposed to probe the time-reversal symmetry of a superconductor. It is shown that a time-reversal symmetry breaking superconductor can be identified by the observation of a fractional flux in connection with a Josephson junction in a special geometry.Comment: 4 pages, 2 figures available upon request, Revtex, MIT-CMT-OC

    Perinatal outcome associated with oligohydramnios in third trimester

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    Background: We aimed to evaluate the effect of Oligohydramnios on fetal outcome in terms of fetal distress, Meconium staining of amniotic fluid, birth weight, Apgar score of newborn babies, NICU admission, early neonatal morbidity and mortality.Methods: This was a prospective study of 156 antenatal patients booked at K. J. Somaiya medical college and research centre during the year January 2012 to December 2013 with gestational age between 30-40wks with AFI<5cms with intact membranes were analyzed for perinatal outcome.Results: The Caesarian section rate for fetal distress was 41% in patients with Oligohydramnios. Meconium staining of amniotic fluid was found in 30.7% patients. APGAR score at 5 minutes <7 was found in 6 patients (3.8%).Conclusions: Oligohydramnios has significant correlation with Caesarean section for fetal distress and low birth weight babies. Oligohydramnios is associated with high rate of pregnancy complication and increased perinatal morbidity and mortality. Oligohydramnios is a frequent occurrence demand careful evaluation, intensive parental counseling, fetal surveillance and proper antepartum and intrapartum care

    Development and Optimization of Solid Lipid Nanoparticle for Topical Delivery

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    The aim of present work was to develop and evaluate solid lipid nanoparticle (SLNs) based gel for topical delivery of anti-inflammatory drug. Material and method Nabumetone loaded SLNs were developed by hot homogenization followed by ultra- sonication technique using compritol 888 ATO as solid lipid and tween 80 as a surfactant. Developed SLNs were evaluated for particle size, entrapment efficiency (EE) and drug release profile. Process and formulation parameters were optimized. Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) studies were carried out on SLNs to mark the change in the drug and lipid modification. The Nabumetone based gels were prepared using carbopol 940 as gelling agent. Results and conclusion: The F14 batch had shown maximum entrapment efficiency up to 94.40 and sustained drug release for more than 7 hours. The particle size of optimized batch (F14) was found to be 16.54. Keywords: Solid lipid nanoparticle, Entrapment efficiency, Colloidal carrier
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