23 research outputs found
Recommended from our members
Effect of rotational inertia on building response to earthquakes via a closed-form solution
In this article, a widely used building model, comprised of uniform coupled flexural and shear beams, herein improved by allowing for the effects of rotational inertia. Closed-form solutions in terms of trigonometric and hyperbolic functions are obtained, allowing for the explicit formulation of period ratios, modal participation factors (MPFs), mode shapes, and mode shape derivatives based solely on displacement response, without coupling with chord rotations, which is the case for the Timoshenko beam model. This makes the model proposed in this study more convenient for assessing building behavior to ground motion, by explicitly highlighting the effect of rotational inertia in their response to earthquakes, making the case for studying its beneficial effects in mitigating response of buildings to ground motion. It is observed that rotational inertia induces mild fundamental period lengthening, while notably reducing period ratios between higher modes and the fundamental one. This can lead to an enhanced response to ground motion showcasing narrow-band characteristics. However, the most severe effect is found to be on the MPF, which is significantly diminished. This leads to important reductions on the overall response, as a consequence of attenuation of the first-mode response, along with severe undercutting of the effects of higher modes. The results demonstrate that without considering the rotational inertia in the assessment of in-plane structural response to horizontal ground motion can lead to conservative results. Moreover, the results showcase the advantages of providing supplemental rotational inertia as a way to improve the seismic behavior of buildings
Downregulation of a UDP-Arabinomutase Gene in Switchgrass (Panicum virgatum L.) Results in Increased Cell Wall Lignin While Reducing Arabinose-Glycans
Background: Switchgrass (Panicum virgatum L.) is a C4 perennial prairie grass and a dedicated feedstock for lignocellulosic biofuels. Saccharification and biofuel yields are inhibited by the plant cell wallâs natural recalcitrance against enzymatic degradation. Plant hemicellulose polysaccharides such as arabinoxylans structurally support and cross-link other cell wall polymers. Grasses predominately have Type II cell walls that are abundant in arabinoxylan, which comprise nearly 25% of aboveground biomass. A primary component of arabinoxylan synthesis is uridine diphosphate (UDP) linked to arabinofuranose (Araf). A family of UDP-arabinopyranose mutase (UAM)/reversible glycosylated polypeptides catalyze the interconversion between UDP-arabinopyranose (UDP-Arap) and UDP-Araf.
Results: The expression of a switchgrass arabinoxylan biosynthesis pathway gene, PvUAM1, was decreased via RNAi to investigate its role in cell wall recalcitrance in the feedstock. PvUAM1 encodes a switchgrass homolog of UDP-arabinose mutase, which converts UDP-Arap to UDP-Araf. Southern blot analysis revealed each transgenic line contained between one to at least seven T-DNA insertions, resulting in some cases, a 95% reduction of native PvUAM1 transcript in stem internodes. Transgenic plants had increased pigmentation in vascular tissues at nodes, but were otherwise similar in morphology to the non-transgenic control. Cell wall-associated arabinose was decreased in leaves and stems by over 50%, but there was an increase in cellulose. In addition, there was a commensurate change in arabinose side chain extension. Cell wall lignin composition was altered with a concurrent increase in lignin content and transcript abundance of lignin biosynthetic genes in mature tillers. Enzymatic saccharification efficiency was unchanged in the transgenic plants relative to the control.
Conclusion: Plants with attenuated PvUAM1 transcript had increased cellulose and lignin in cell walls. A decrease in cell wall-associated arabinose was expected, which was likely caused by fewer Araf residues in the arabinoxylan. The decrease in arabinoxylan may cause a compensation response to maintain cell wall integrity by increasing cellulose and lignin biosynthesis. In cases in which increased lignin is desired, e.g., feedstocks for carbon fiber production, downregulated UAM1 coupled with altered expression of other arabinoxylan biosynthesis genes might result in even higher production of lignin in biomass
ARCHITECTURAL ENGINEERING AS A PROFESSION: REPORT ON RESEARCH LEADING TO A CURRICULUM REVISION
Increased leukotriene E4 excretion during antigen-induced bronchoconstriction in allergic sheep
Recycled versus Natural-Rubber Fiber-Reinforced Bearings for Base Isolation: Review of the Experimental Findings
The motivations of psychotherapists: an inâdepth survey
Background
Examining the motivations of psychotherapists has not been a popular topic of systematic research. Knowing why people want to become therapists is clearly important because this factor will inevitably impact on therapeutic outcomes. The absence of researchâled knowledge on therapistsⲠmotivations allows this key issue to remain a relatively unattended focus within reflective practice and personal development.
Aim
To collect data about therapistsⲠmotivations from a large number of practitioners so that core findings could be generalised to the wider profession.
Method
A total of 540 psychotherapists completed an online survey with significant numbers offering supporting qualitative data. Quantitative data were analysed using descriptive and inferential statistics. Qualitative data were subject to thematic and textual analysis.
Results
A large majority of therapists believe that their career choice was influenced by unconscious motivations, that their motivations are likely to change over time and that their own psychic wounds can contribute to effective therapy.
Conclusion
Psychotherapists are clearly prepared to reflect, in depth, on why they have been drawn to the profession. The fact that an awareness of therapistsⲠmotivations may be variable that they may change over time and can be linked to personal vulnerability suggests that the topic should be an integral part of practitionersⲠongoing personal development and a discrete focus in formal training programmes