Cultural Predilection On Design In Planning Ecological Sanitation In Northern Uganda

Poor sanitation and open defecation is a major concern in many parts of the world. Ecological sanitation is a possible alternative to the global issue by using dry toilet systems that allow for recycling the waste for other uses. The purpose of this thesis is to determine the cultural perception and design implications toward ecological sanitation in developing countries. By surveying the local population in the proposed environments and implementing a corresponding system, the sanitation system has a much higher chance of sustainability and success. In Northern Uganda, the population was surveyed through a questionnaire and a Visual Preference Survey to determine current conditions, immediate needs, cultural preferences, and attitudes toward the design of sanitation types with the main focus on privacy, placement, type and gender-specific facilities. Results demonstrated that the majority of the population was interested in learning more to improve sanitation and reuse waste for agricultural productivity

Oral Memoirs of Charles McCall

An oral history interview with Charles McCall, MD, former associate dean of the Tulsa Medical College, and later dean of the College of Medicine at the University of Oklahoma Health Sciences Center.N

Using Batch Studies to Optimize On-site Wastewater Treatment Systems for Removing Emerging Contaminants

Decentralized or "on-site" wastewater treatment systems offer a number of advantages over conventional centralized systems, including reduced capital costs, adaptability, and ease of implementation for water reuse. While the ability of these systems to remove traditional wastewater constituents is well known, their ability to address contaminants of emerging environmental and public health concern, such as pharmaceuticals and personal care products, is less established. This report explores the effects of various design and operating parameters on emerging contaminant removal, with a focus on the use of batch studies to identify which removal mechanisms are most relevant. The results of an initial batch study, using wastewater from the Jordan Lake Business Park (Apex, NC), suggest that mixed media consisting of gravel, Stalite, and sand were more effective than sand alone at removing five selected contaminants from the bulk solution.Master of Science in Environmental Engineerin

Improving Cavity Enhanced Spectroscopy of Molecular Ions in the Mid-Infrared With Up-Conversion Detection and Brewster-Plate Spoilers

The performance of sensitive spectroscopic methods in the mid-IR is often limited by fringing due to parasitic etalons and the background noise in mid-infrared detectors. In particular, the technique Noise Immune Cavity Enhanced Optical Heterodyne Velocity Modulation Spectroscopy (NICE-OHVMS), which is capable of determining the frequencies of strong rovibrational transitions of molecular ions with sub-MHz uncertainty, needs improved sensitivity in order to probe weaker transitions. In this work, we have implemented up-conversion detection with NICE-OHVMS in the 3.2 - 3.9 μm region to enable the use of faster and more sensitive detectors which cover visible wavelengths. The higher bandwidth enabled detection at optimized heterodyne frequencies, which increased the overall signal from the H43 cation by a factor of three and was able to resolve sub-Doppler features which had previously overlapped. Also, we demonstrate the effectiveness of Brewster-plate spoilers to remove fringes due to parasitic etalons in a cavity enhanced technique. Together, these improvements reduced the instrument\u27s noise equivalent absorption to 5.9 X 10-11 cm-1 Hz-1/2, which represents a factor of 34 improvement in sensitivity compared to previous implementations of NICE-OHVMS. This work will enable extended high-precision spectroscopic surveys of H43 and other important molecular ions

Note and Comment

The Passing of State Control over Railway Rates; Constitutionality of the New York Workmen\u27s Compensation Act; Must a Passenger Go on the Same Train with His Baggage?; Implied Reservation of Easements; Extent of the City\u27s Right, Under the Power of Eminent Domain, to Exemption from Liability for Consequential Damages Under the Rule of Damnum Absque Injuria

Trends, wealth inequalities and the role of the private sector in caesarean section in the Middle East and North Africa : A repeat cross-sectional analysis of population-based surveys

Peer reviewedPublisher PD

KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis

Sepsis-induced myeloid-derived suppressor cells (MDSCs) increase mortality risk. We previously identified that long non-coding RNA Hotairm1 supports myeloid precursor shifts to Gr1+CD11b+ MDSCs during mouse sepsis. A major unanswered question is what molecular processes control Hotairm1 expression. In this study, we found by a genetic deletion that a specific PU.1-binding site is indispensable in controlling Hotairm1 transcription. We then identified H3K4me3 and H3K27me3 at the PU.1 site on the Hotairm1 promoter. Controlling an epigenetic switch of Hotairm1 transcription by PU.1 was histone KDM6A demethylase for H3K27me3 that derepressed its transcription with possible contributions from Ezh2 methyltransferase for H3K27me3. KDM6A knockdown in MDSCs increased H3K27me3, decreased H3K4me3, and inhibited Hotairm1 transcription activation by PU.1. These results enlighten clinical translation research of PU.1 epigenetic regulation as a potential sepsis immune-checkpoint treatment site