335 research outputs found
Carbamazepine on a carbamazepine monolayer forms unique 1D supramolecular assemblies
High-resolution STM imaging of the structures formed by carbamazepine molecules adsorbed onto a pseudo-ordered carbamazepine monolayer on Au(111) shows the formation of previously unreported 1-dimensional supramolecular assemblies
Controlling a spillover pathway with the molecular cork effect
Spillover of reactants from one active site to another is important in heterogeneous catalysis and has recently been shown to enhance hydrogen storage in a variety of materials. The spillover of hydrogen is notoriously hard to detect or control. We report herein that the hydrogen spillover pathway on a Pd/Cu alloy can be controlled by reversible adsorption of a spectator molecule. Pd atoms in the Cu surface serve as hydrogen dissociation sites from which H atoms can spillover onto surrounding Cu regions. Selective adsorption of CO at these atomic Pd sites is shown to either prevent the uptake of hydrogen on, or inhibit its desorption from, the surface. In this way, the hydrogen coverage on the whole surface can be controlled by molecular adsorption at a minority site, which we term a âmolecular corkâ effect. We show that the molecular cork effect is present during a surface catalysed hydrogenation reaction and illustrate how it can be used as a method for controlling uptake and release of hydrogen in a model storage syste
Is âfailure to treatâ a treatment failure?
Over-servicing in dentistry has been widely reported on and
censured due to the potential physical, social and financial
harms it can cause a patient. In contrast, under-treatment
is less often noticed or raised as a concern as it seldom
presents with overt signs of carelessness or disregard. In
addition, it is usually not accompanied by any time or financial
burdens, thus patients rarely complain about it. While some
practitioners may argue that failure to treat is a form of
negligence, this paper will explore if, and when it could be
justified. While practitioners may never reach a consensus
agreement, the ultimate message is that all treatment should
be patient centred and should only commence following their
educated, considered, autonomous, and voluntary consent.https://www.sada.co.za/the-sadjam2022Prosthodontic
Discovery of a Brown Dwarf Companion to Gliese 570ABC: A 2MASS T Dwarf Significantly Cooler than Gliese 229B
We report the discovery of a widely separated (258\farcs3\pm0\farcs4) T
dwarf companion to the Gl 570ABC system. This new component, Gl 570D, was
initially identified from the Two Micron All Sky Survey (2MASS). Its
near-infrared spectrum shows the 1.6 and 2.2 \micron CH absorption bands
characteristic of T dwarfs, while its common proper motion with the Gl 570ABC
system confirms companionship. Gl 570D (M = 16.470.07) is nearly a
full magnitude dimmer than the only other known T dwarf companion, Gl 229B, and
estimates of L = (2.80.3)x10 L_{\sun} and T = 75050
K make it significantly cooler and less luminous than any other known brown
dwarf companion. Using evolutionary models by Burrows et al. and an adopted age
of 2-10 Gyr, we derive a mass estimate of 5020 M for this object.Comment: 13 pages, 2 figures, 2 tables, accepted by ApJ
Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokinesâan exploratory study
<p>Background: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear. Whilst cytokines can induce corticosteroid insensitivity in-vitro, how current and former smoking affects airway cytokine concentrations and their responses to oral corticosteroids in stable chronic asthma is unclear.</p>
<p>Objectives: To examine blood and sputum cytokine concentrations in never, ex and current smokers with asthma before and after oral corticosteroids.</p>
<p>Methods: Exploratory study utilizing two weeks of oral dexamethasone (equivalent to 40 mg/day prednisolone) in 22 current, 21 never and 10 ex-smokers with asthma. Induced sputum supernatant and plasma was obtained before and after oral dexamethasone. 25 cytokines were measured by multiplex microbead system (Invitrogen, UK) on a Luminex platform.</p>
<p>Results: Smokers with asthma had elevated sputum cytokine interleukin (IL) -6, -7, and -12 concentrations compared to never smokers with asthma. Few sputum cytokine concentrations changed in response to dexamethasone IL-17 and IFNÎą increased in smokers, CCL4 increased in never smokers and CCL5 and CXCL10 reduced in ex-smokers with asthma. Ex-smokers with asthma appeared to have evidence of an ongoing corticosteroid resistant elevation of cytokines despite smoking cessation. Several plasma cytokines were lower in smokers wi</p>
<p>Conclusion: Cigarette smoking in asthma is associated with a corticosteroid insensitive increase in multiple airway cytokines. Distinct airway cytokine profiles are present in current smokers and never smokers with asthma and could provide an explanatory mechanism for the altered clinical behavior observed in smokers with asthma.</p>
Quantum flutter of supersonic particles in one-dimensional quantum liquids
The non-equilibrium dynamics of strongly correlated many-body systems
exhibits some of the most puzzling phenomena and challenging problems in
condensed matter physics. Here we report on essentially exact results on the
time evolution of an impurity injected at a finite velocity into a
one-dimensional quantum liquid. We provide the first quantitative study of the
formation of the correlation hole around a particle in a strongly coupled
many-body quantum system, and find that the resulting correlated state does not
come to a complete stop but reaches a steady state which propagates at a finite
velocity. We also uncover a novel physical phenomenon when the impurity is
injected at supersonic velocities: the correlation hole undergoes long-lived
coherent oscillations around the impurity, an effect we call quantum flutter.
We provide a detailed understanding and an intuitive physical picture of these
intriguing discoveries, and propose an experimental setup where this physics
can be realized and probed directly.Comment: 13 pages, 9 figure
Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care
Structuring International Financial Support for Climate Change Mitigation in Developing Countries
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