335 research outputs found

    Do state and trait measures measure states and traits? The case of community-dwelling caregivers of older adults

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    Spielberger’s state and trait anxiety and anger scales are widely used and documented, but there is little or no direct evidence that they actually measure their respective state and trait aspects as was intended. We conducted latent state-trait analyses on data collected from 310 community-dwelling caregivers of older adult care recipients and found that (a) both state and trait scales reflected a mixture of state and trait aspects of their latent constructs, (b) state scales reflected more state-like variance than did corresponding trait scales, but (c) both state and trait scales were dominated by stable trait-like variance. Follow-up bivariate latent state-trait analyses indicated that correlations between trait components of anger and anxiety correlated more strongly with trait components of caregiver–care recipient mutually communal behavior and care recipient problem behavior than did state–state component correlations. Implications for the measurement of state and trait components of psychological constructs are discussed

    A trait-state model of trust propensity: Evidence from two career transitions

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    Trust propensity is typically conceptualized as a stable, trait-like, exogenous variable. Drawing on the social investment principle of personality change, we argue that trust propensity has situationally specific components and is likely to be less stable during periods of career transition. Using a latent curve-latent state-trait model, we present evidence that suggests that trust propensity has stable (trait) and unstable (state) components during career transition periods and that it has the potential to change over time. Our results are replicated across two, transitional workplace populations during a process of (re)socialization into an organization. In our second study, we also expand our focus to examine correlates of trust propensity and demonstrate the relationship between state and trait trust propensity and cognitive depletion. Our paper significantly extends knowledge of the nature of trust propensity and raises questions about the stability of this construct, one of the core tenets of trust theory

    An intellectual disability syndrome with single nucleotide variants in <i>O-GlcNAc Transferase</i>

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    Contains fulltext : 220584.pdf (Publisher’s version ) (Open Access)Intellectual disability (ID) is a neurodevelopmental condition that affects ~1% of the world population. In total 5-10% of ID cases are due to variants in genes located on the X chromosome. Recently, variants in OGT have been shown to co-segregate with X-linked intellectual disability (XLID) in multiple families. OGT encodes O-GlcNAc transferase (OGT), an essential enzyme that catalyses O-linked glycosylation with β-N-acetylglucosamine (O-GlcNAc) on serine/threonine residues of thousands of nuclear and cytosolic proteins. In this review, we compile the work from the last few years that clearly delineates a new syndromic form of ID, which we propose to classify as a novel Congenital Disorder of Glycosylation (OGT-CDG). We discuss potential hypotheses for the underpinning molecular mechanism(s) that provide impetus for future research studies geared towards informed interventions

    Magnetic properties of pure and Gd doped EuO probed by NMR

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    An Eu NMR study in the ferromagnetic phase of pure and Gd doped EuO was performed. A complete description of the NMR lineshape of pure EuO allowed for the influence of doping EuO with Gd impurities to be highlighted. The presence of a temperature dependent static magnetic inhomogeneity in Gd doped EuO was demonstrated by studying the temperature dependence of the lineshapes. The results suggest that the inhomogeneity in 0.6% Gd doped EuO is linked to colossal magnetoresistance. The measurement of the spin-lattice relaxation times as a function of temperature led to the determination of the value of the exchange integral J as a function of Gd doping. It was found that J is temperature independent and spatially homogeneous for all the samples and that its value increases abruptly with increasing Gd doping.Comment: 14 pages, 10 figures, to be published in Physical Review

    Revised estimates of dimension and exercise variance components in assessment center postexercise dimension ratings

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    The authors reanalyzed assessment center (AC) multitrait–multimethod (MTMM) matrices containing correlations among postexercise dimension ratings (PEDRs) reported by F. Lievens and J. M. Conway (2001). Unlike F. Lievens and J. M. Conway, who used a correlated dimension-correlated uniqueness model, we used a different set of confirmatory-factor-analysis–based models (1-dimension-correlated Exercise and 1-dimension-correlated uniqueness models) to estimate dimension and exercise variance components in AC PEDRs. Results of reanalyses suggest that, consistent with previous narrative reviews, exercise variance components dominate over dimension variance components after all. Implications for AC construct validity and possible redirections of research on the validity of ACs are discussed. Assessment centers (ACs) exhibit some of the highest criterion-related validities among alternative predictors of job performance (Gaugler, Rosenthal, Thornton, &amp; Bentson, 1987; Schmidt &amp; Hunter, 1998). Nevertheless, the construct validity of AC postex-ercise dimension ratings (PEDRs), that is, dimension ratings that are made at the completion of each exercise, has continued to be called into question for over 20 years (Lance, Newbolt, et al.

    What is Method Variance and How Can We Cope With It? A Panel Discussion

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    A panel of experts describes the nature of, and remedies for, method variance. In an attempt to help the reader understand the nature of method variance, the authors describe their experiences with method variance both on the giving and the receiving ends of the editorial review process, as well as their interpretation of other reviewers’ comments. They then describe methods of data analysis and research design, which have been used for detecting and eliminating the effects of method variance. Most methods have some utility, but none prevent the researcher from making faulty inferences. The authors conclude with suggestions for resolving disputes about method variance

    The Dual Impact of HIV-1 Infection and Aging on NaĂŻve CD4+ T-Cells: Additive and Distinct Patterns of Impairment

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    HIV-1-infected adults over the age of 50 years progress to AIDS more rapidly than adults in their twenties or thirties. In addition, HIV-1-infected individuals receiving antiretroviral therapy (ART) present with clinical diseases, such as various cancers and liver disease, more commonly seen in older uninfected adults. These observations suggest that HIV-1 infection in older persons can have detrimental immunological effects that are not completely reversed by ART. As naïve T-cells are critically important in responses to neoantigens, we first analyzed two subsets (CD45RA+CD31+ and CD45RA+CD31-) within the naïve CD4+ T-cell compartment in young (20–32 years old) and older (39–58 years old), ART-naïve, HIV-1 seropositive individuals within 1–3 years of infection and in age-matched seronegative controls. HIV-1 infection in the young cohort was associated with lower absolute numbers of, and shorter telomere lengths within, both CD45RA+CD31+CD4+ and CD45RA+CD31-CD4+ T-cell subsets in comparison to age-matched seronegative controls, changes that resembled seronegative individuals who were decades older. Longitudinal analysis provided evidence of thymic emigration and reconstitution of CD45RA+CD31+CD4+ T-cells two years post-ART, but minimal reconstitution of the CD45RA+CD31-CD4+ subset, which could impair de novo immune responses. For both ART-naïve and ART-treated HIV-1-infected adults, a renewable pool of thymic emigrants is necessary to maintain CD4+ T-cell homeostasis. Overall, these results offer a partial explanation both for the faster disease progression of older adults and the observation that viral responders to ART present with clinical diseases associated with older adults

    On the alleged simplicity of impure proof

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    Roughly, a proof of a theorem, is “pure” if it draws only on what is “close” or “intrinsic” to that theorem. Mathematicians employ a variety of terms to identify pure proofs, saying that a pure proof is one that avoids what is “extrinsic,” “extraneous,” “distant,” “remote,” “alien,” or “foreign” to the problem or theorem under investigation. In the background of these attributions is the view that there is a distance measure (or a variety of such measures) between mathematical statements and proofs. Mathematicians have paid little attention to specifying such distance measures precisely because in practice certain methods of proof have seemed self- evidently impure by design: think for instance of analytic geometry and analytic number theory. By contrast, mathematicians have paid considerable attention to whether such impurities are a good thing or to be avoided, and some have claimed that they are valuable because generally impure proofs are simpler than pure proofs. This article is an investigation of this claim, formulated more precisely by proof- theoretic means. After assembling evidence from proof theory that may be thought to support this claim, we will argue that on the contrary this evidence does not support the claim
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