Estrategias de formulación de los mercados de abasto y su influencia en la sociedad y cultura

Los mercados de abasto es una de las infraestructuras más antiguas de comercialización que convive con el retail moderno, manteniendo su posicionamiento, gracias no solo a la ventaja competitiva del producto fresco sino a los impactos sociales y culturales que generan. Por otro lado los supermercados y su gran desarrollo logístico operacional y fuerte crecimiento, han modificado los hábitos de compra del consumidor, con la creación de distintos formatos de venta, posicionándose cada vez más en la preferencia de compra, pudiéndose perder ese potencial beneficio sociocultural, por lo que los mercados de abasto tradicionales necesitan implementar nuevas estrategias que les permita seguir desarrollando esos aspectos relevantes de la sociedad, recuperando sus orígenes de ser edificaciones potencialmente influyentes de su entorno, a través de intervenciones que generan vinculaciones sociales y culturales, encontrándose en la investigación soluciones como: Beneficios sociales a través de la integración estratégica de comerciantes y vecinos, Beneficios urbanos a través de la integración con su entorno, Beneficios culturales a través de nuevos servicios con valor agregado, mejoras de los servicios internos implementando el diseño emocional y merchandising en la exhibición

Cyanobacterial and chloroplast F1-ATPases: cross-reconstitution of photophosphorylation and subunit immunological relationships

The photosynthetic F1-ATPase from the cyanobacterium Spirulina platensis was recently purified in a five-subunit, reconstitutively active form (Hicks, D.B. and Yocum, C.F. (1986) Arch. Biochem. Biophys. 245, 220-229). Here we report on the similarities of the cyanobacterial F1 to the higher plant chloroplast F1 (CF1), as judged by two distinct methods. The ability of each coupling factor to reconstitute photophosphorylation in photosynthetic membranes depleted of F1 content by 2 M NaBr treatment was tested. Addition of either the homologous enzyme (e.g., Spirulina F1, Spirulina membranes) or the heterologous enzyme (e.g., spinach CF1 Spirulina membranes) to depleted membranes increased the rate of phenazine methosulfate-dependent cyclic photophosphorylation from nearly zero to up to 70 [mu]mol ATP/h per mg Chl. Antibodies against four subunits of CF1 ([alpha], [gamma], [delta] and [var epsilon]) and against [beta] of Escherichia coli F1 were reacted with the Spirulina enzyme by protein blotting. The [alpha], [beta] and [gamma] subunits of Spirulina F1 cross-reacted with antibodies against the corresponding subunits from spinach. The cross-reactivity of the [gamma] subunit correlated with previous observations that Spirulina membrane ATPase activity can be modulated by light and dithiothreitol, in a similar fashion to their effect on the enzyme from spinach chloroplasts. The ability of cyanobacterial and chloroplast enzymes to restore activity to heterologous membranes in the absence of immunological similarities between their respective [delta] and [var epsilon] subunits may suggest that structural features other than particular amino acid sequences of these subunits are paramount in their roles in binding F1 to the membrane and in sealing proton leaks.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26048/1/0000121.pd

Differential Cross Section for γ d →ωd Using CLAS at Jefferson Lab

The cross section for coherent ω-meson photoproduction off the deuteron has been measured for the first time as a function of the momentum transfer t=(Pγ−Pω)2 and photon energy Eγ using the CLAS detector at the Thomas Jefferson National Accelerator Facility. The cross sections are measured in the energy range 1.4 γ\u3c3.4 GeV. A model based on ω−N rescattering is consistent with the data at low and intermediate momentum transfer, |t|. For 2.8 γ\u3c3.4 GeV, the total cross-section of ω−N scattering, based on fits within the framework of the Vector Meson Dominance model, is in the range of 30–40 mb

Coronary artery disease risk reduction in HIV-infected persons: a comparative analysis

Despite an increased risk of coronary artery disease (CAD) in persons infected with human immunodeficiency virus (HIV), few data are available on primary prevention of CAD in this population. In this retrospective cohort study, HIV-infected patients treated in an academic medical center HIV Specialty Clinic between 1996 and 2010 were matched by age, gender, and ethnicity to a cohort of presumed uninfected persons followed in an academic medical center Internal Medicine primary care clinic. We compared CAD primary prevention care practices between the two clinics, including use of aspirin, HMG-CoA reductase inhibitors (“statins”), and anti-hypertensive drugs. CAD risk between the two groups was assessed with 10-year Framingham CAD risk scores. In the comparative analysis, 890 HIV-infected persons were compared to 807 controls. Ten-year Framingham CAD Risk Scores were similar in the two groups (median, 3; interquartile range [IQR], 0–5). After adjusting for relevant risk factors, HIV-infected persons were less likely to be prescribed aspirin (odds ratio [OR] 0.53; 95% confidence interval [CI], 0.40–0.71), statins (OR, 0.70; 95% CI, 0.53–0.92), and anti-hypertensive drugs (OR, 0.63; 95% CI, 0.50–0.79) than persons in the control group. In summary, when compared to demographically similar uninfected persons, HIV-infected persons treated in an HIV specialty clinic were less likely to be prescribed medications appropriate for CAD risk reduction. Improving primary preventative CAD care in HIV specialty clinic populations is an important step toward diminishing risk of heart disease in HIV-infected persons

Diminished physical function in older HIV-infected adults in the Southeastern U.S. despite successful antiretroviral therapy

As antiretroviral therapy efficacy improves, HIV is gradually being recognized more as a chronic disease within the aging HIV-infected population. While these individuals are surviving into old age, they may, however, be experiencing “accelerated aging” with greater declines in physical function than that observed among comparably matched individuals free of HIV. This decline is not well understood and it remains unclear if physical decline correlates with the degree of immunosuppression based on CD4 lymphocyte nadir

Measurements of ep → e′π+π-p′ Cross Sections with CLAS at 1.40 GeV \u3c W \u3c 2.0 GeV and 2.0 GeV² \u3c Q² \u3c 5.0 GeV²

This paper reports new exclusive cross sections for ep → e′π+π-p′ using the CLAS detector at Jefferson Laboratory. These results are presented for the first time at photon virtualities 2.0GeV2 2 \u3c 5.0GeV2 in the center-of-mass energy range 1.4 GeV \u3c W \u3c 2.0 GeV, which covers a large part of the nucleon resonance region. Using a model developed for the phenomenological analysis of electroproduction data, we see strong indications that the relative contributions from the resonant cross sections at W \u3c 1.74 GeV increase with Q2. These data considerably extend the kinematic reach of previous measurements. Exclusive ep → e′π+π-p′ cross section measurements are of particular importance for the extraction of resonance electrocouplings in the mass range above 1.6 GeV

1946: Abilene Christian College Bible Lectures - Full Text

Abilene Christian College Lectures - 1946 INTRODUCTION It has been our purpose at Abilene Christian College down through the years to provide in the Annual Bible Lectureship programs that which would be appropriate for the time and most useful to the students and to the Lectureship visitors. The general subject for the 1946 lectures is “Things That Cannot Be Shaken.” This subject was selected because one of the battles, if not the battle, which the church faces today is against those forces which would undermine the bases of gospel truth. Many denominational leaders, in one way or another, are denying even the fundamentals of fundamentals— God is, the Bible is God\u27s Revelation, Jesus Christ is the Son of God and The Kingdom Cannot Be Shaken. Many others, some without knowing what they do, are accepting false teachings and ideologies which, if allowed to run their course, will destroy all true religion. It is believed that the 1946 lectures and this edition of the lectures will help toward establishing in the hearts of men the truth of the important theses discussed. It was the purpose of those who arranged the program that the Lectureship should, also, hold up Christianity as a working, practical religion; hence, the meetings on “Work in New Fields” and “The Church at Work.” The attendance of this Lectureship was the largest in the history of these yearly meetings. On Wednesday evening Brother Nichol spoke to a crowd of approximately 1700 persons. Other evening lectures were attended by crowds almost as large. Visitors came from more than a score of States and, also, from Canada and Mexico. It is the hope of all of us at the College that the fellowship of the 1946 Lectureship and the instruction given by the various speakers will continue to do good for years without end. DON H. MORRIS

A cross-sectional analysis of HIV and hepatitis C clinical trials 2007 to 2010: the relationship between industry sponsorship and randomized study design

Abstract Background The proportion of clinical research sponsored by industry will likely continue to expand as federal funds for academic research decreases, particularly in the fields of HIV/AIDS and hepatitis C (HCV). While HIV and HCV continue to burden the US population, insufficient data exists as to how industry sponsorship affects clinical trials involving these infectious diseases. Debate exists about whether pharmaceutical companies undertake more market-driven research practices to promote therapeutics, or instead conduct more rigorous trials than their non-industry counterparts because of increased resources and scrutiny. The ClinicalTrials.gov registry, which allows investigators to fulfill a federal mandate for public trial registration, provides an opportunity for critical evaluation of study designs for industry-sponsored trials, independent of publication status. As part of a large public policy effort, the Clinical Trials Transformation Initiative (CTTI) recently transformed the ClinicalTrials.gov registry into a searchable dataset to facilitate research on clinical trials themselves. Methods We conducted a cross-sectional analysis of 477 HIV and HCV drug treatment trials, registered with ClinicalTrials.gov from 1 October 2007 to 27 September 2010, to study the relationship of study sponsorship with randomized study design. The likelihood of using randomization given industry (versus non-industry) sponsorship was reported with prevalence ratios (PR). PRs were estimated using crude and stratified tabular analysis and Poisson regression adjusting for presence of a data monitoring committee, enrollment size, study phase, number of study sites, inclusion of foreign study sites, exclusion of persons older than age 65, and disease condition. Results The crude PR was 1.17 (95% CI 0.94, 1.45). Adjusted Poisson models produced a PR of 1.13 (95% CI 0.82, 1.56). There was a trend toward mild effect measure modification by study phase, but this was not statistically significant. In stratified tabular analysis the adjusted PR was 1.14 (95% CI 0.78, 1.68) among phase 2/3 trials and 1.06 (95% CI 0.50, 2.22) among phase 4 trials. Conclusions No significant relationship was found between industry sponsorship and use of randomization in trial design in this cross-sectional study. Prospective studies evaluating other aspects of trial design may shed further light on the relationship between industry sponsorship and appropriate trial methodology

Incident Sexually Transmitted Infection as a Biomarker for High-Risk Sexual Behavior After Diagnosis of Acute HIV

Sexually transmitted infection (STI) diagnosis following diagnosis of acute HIV infection (AHI) indicates ongoing high-risk sexual behavior and possible risk of HIV transmission. We assessed predictors of STI acquisition and the effect of time since care entry on STI incidence in AHI patients in care and receiving consistent risk-reduction messaging

A comparison of forward and backward pp pair knockout in 3He(e,e'pp)n

Measuring nucleon-nucleon Short Range Correlations (SRC) has been a goal of the nuclear physics community for many years. They are an important part of the nuclear wavefunction, accounting for almost all of the high-momentum strength. They are closely related to the EMC effect. While their overall probability has been measured, measuring their momentum distributions is more difficult. In order to determine the best configuration for studying SRC momentum distributions, we measured the $^3$He$(e,e'pp)n$ reaction, looking at events with high momentum protons ($p_p > 0.35$ GeV/c) and a low momentum neutron ($p_n< 0.2$ GeV/c). We examined two angular configurations: either both protons emitted forward or one proton emitted forward and one backward (with respect to the momentum transfer, $\vec q$). The measured relative momentum distribution of the events with one forward and one backward proton was much closer to the calculated initial-state $pp$ relative momentum distribution, indicating that this is the preferred configuration for measuring SRC.Comment: 8 pages, 9 figures, submitted to Phys Rev C. Version 2 incorporates minor corrections in response to referee comment