Spectacular Subjects: The Violent Erotics of Imperial Visual Culture

The central concerns of this project are the visual constructions of feminine and feminist subjectivities, significations and semiotics of the (brown) female body, and the pleasures and power of global visual culture. I consider the primary visual fields that seek to tell the story of Pakistani women, and Muslim woman more broadly, after September 11th, 2001. Specifically, I offer detailed case studies of three visual stories: international human rights sensation Mukhtar Mai; twice elected Prime Minister of Pakistan and first woman to lead a Muslim country Benazir Bhutto; and female terrorists/religious martyrs of the Red Mosque events in Islamabad, Pakistan. I locate the relevance of these visual stories on three axes − human rights, democratization and the war on terror − where each operates as an arm of, what Jasbir Paur (2007) calls, the U.S. hetero-normative nation. I also examine the structures of affect, pleasure and eroticism that are embedded in these popularized representations and narrations in the U.S. cultural context. Finally, I offer ways to reread the potential radical subjectivities or possibilities that these visual subjects and their political labor open up

Efficacy of HIV/STI behavioral interventions for heterosexual African American men in the United States: a meta-analysis

This meta-analysis estimates the overall efficacy of HIV prevention interventions to reduce HIV sexual risk behaviors and sexually transmitted infections (STIs) among heterosexual African American men. A comprehensive search of the literature published during 1988–2008 yielded 44 relevant studies. Interventions significantly reduced HIV sexual risk behaviors and STIs. The stratified analysis for HIV sexual risk behaviors indicated that interventions were efficacious for studies specifically targeting African American men and men with incarceration history. In addition, interventions that had provision/referral of medical services, male facilitators, shorter follow-up periods, or emphasized the importance of protecting family and significant others were associated with reductions in HIV sexual risk behaviors. Meta-regression analyses indicated that the most robust intervention component is the provision/referral of medical services. Findings indicate that HIV interventions for heterosexual African American men might be more efficacious if they incorporated a range of health care services rather than HIV/STI-related services alone

Smart Partnerships to Increase Equity in Education

This exploratory analysis of smart partnerships identifies the risk of increasing the digital divide with the deployment of data analytics. Smart partnerships in education appear to include a process of evolution into a synergy of strategic and holistic approaches that enhance the quality of education with digital technologies, harnessing ICT “smartly” both in relation to learning and support of the partnership itself. To guide strategic development as data analytics start to emerge in the schooling sector, two cases of large multi-stakeholder partnership initiatives aiming to increase access to education with ICT nationwide in India and Malaysia are analyzed. Mapping the partners’ collaborative activities in Davis’ Arena of change with digital technologies enabled the identification of both local and global influences in that ecological framework, which inform the choice of partners and their roles to increase equitable access to education. Research and development is recommended so that multi-stakeholder partnerships leverage data analytics alongside technology enhanced learning in the schooling sector with strategies that proactively increase equity

Microbiota Modulate Host Gene Expression via MicroRNAs

Microbiota are known to modulate host gene expression, yet the underlying molecular mechanisms remain elusive. MicroRNAs (miRNAs) are importantly implicated in many cellular functions by post-transcriptionally regulating gene expression via binding to the 3′-untranslated regions (3′-UTRs) of the target mRNAs. However, a role for miRNAs in microbiota-host interactions remains unknown. Here we investigated if miRNAs are involved in microbiota-mediated regulation of host gene expression. Germ-free mice were colonized with the microbiota from pathogen-free mice. Comparative profiling of miRNA expression using miRNA arrays revealed one and eight miRNAs that were differently expressed in the ileum and the colon, respectively, of colonized mice relative to germ-free mice. A computational approach was then employed to predict genes that were potentially targeted by the dysregulated miRNAs during colonization. Overlapping the miRNA potential targets with the microbiota-induced dysregulated genes detected by a DNA microarray performed in parallel revealed several host genes that were regulated by miRNAs in response to colonization. Among them, Abcc3 was identified as a highly potential miRNA target during colonization. Using the murine macrophage RAW 264.7 cell line, we demonstrated that mmu-miR-665, which was dysregulated during colonization, down-regulated Abcc3 expression by directly targeting the Abcc3 3′-UTR. In conclusion, our study demonstrates that microbiota modulate host microRNA expression, which could in turn regulate host gene expression

Efficacy of Structural-Level Condom Distribution Interventions: A Meta-Analysis of U.S. and International Studies, 1998–2007

This systematic review examines the overall efficacy of U.S. and international-based structural-level condom distribution interventions (SLCDIs) on HIV risk behaviors and STIs and identifies factors associated with intervention efficacy. A comprehensive literature search of studies published from January 1988 through September 2007 yielded 21 relevant studies. Significant intervention effects were found for the following outcomes: condom use, condom acquisition/condom carrying, delayed sexual initiation among youth, and reduced incident STIs. The stratified analyses for condom use indicated that interventions were efficacious for various groups (e.g., youth, adults, males, commercial sex workers, clinic populations, and populations in areas with high STI incidence). Interventions increasing the availability of or accessibility to condoms or including additional individual, small-group or community-level components along with condom distribution were shown to be efficacious in increasing condom use behaviors. This review suggests that SLCDIs provide an efficacious means of HIV/STI prevention