Do note disclosures influence value relevance more after financial statement placement becomes more uniformly prominent? Evidence from ASU 2011-05

We examine whether financial statement note disclosures play an enhanced role in value relevance when the placement of line items among financial statements becomes more uniformly prominent. We consider ASU 2011-05, which prohibited reporting other comprehensive income (OCI) in the statement of changes in stockholders’ equity, and report two main findings. First, using a larger sample and longer time period than early studies examining ASU 2011-05, we document that, relative to firms unaffected by this prohibition, firms required to change OCI placement exhibited positive changes in OCI value relevance after ASU 2011-05 became effective, in line with the FASB’s stated goal of raising OCI prominence. This finding resolves the seemingly puzzling findings of early studies, which documented an unexpected incremental decrease in OCI value relevance for these firms. Second, we find that this effect is enhanced when OCI-related note disclosures are more specific and numeric, and are more readable, more stable, or shorter in length. Collectively, our findings suggest that financial statement placement and note disclosure characteristics interact in a manner such that when financial statement line items influence valuation to a greater extent via prominent placement, qualitative characteristics of accompanying note disclosures assume this role more prominently as well

Silicon Derived from Glass Bottles as Anode Materials for Lithium Ion Full Cell Batteries.

Every year many tons of waste glass end up in landfills without proper recycling, which aggravates the burden of waste disposal in landfill. The conversion from un-recycled glass to favorable materials is of great significance for sustainable strategies. Recently, silicon has been an exceptional anode material towards large-scale energy storage applications, due to its extraordinary lithiation capacity of 3579 mAh g-1 at ambient temperature. Compared with other quartz sources obtained from pre-leaching processes which apply toxic acids and high energy-consuming annealing, an interconnected silicon network is directly derived from glass bottles via magnesiothermic reduction. Carbon-coated glass derived-silicon (gSi@C) electrodes demonstrate excellent electrochemical performance with a capacity of ~1420 mAh g-1 at C/2 after 400 cycles. Full cells consisting of gSi@C anodes and LiCoO2 cathodes are assembled and achieve good initial cycling stability with high energy density

Epitope mapping of PfCP-2.9, an asexual blood-stage vaccine candidate of Plasmodium falciparum

<p>Abstract</p> <p>Background</p> <p>Apical membrane antigen 1 (AMA-1) and merozoite surface protein 1 (MSP1) of <it>Plasmodium falciparum </it>are two leading blood-stage malaria vaccine candidates. A <it>P. falciparum </it>chimeric protein 2.9 (PfCP-2.9) has been constructed as a vaccine candidate, by fusing AMA-1 domain III (AMA-1 (III)) with a C-terminal 19 kDa fragment of MSP1 (MSP1-19) via a 28-mer peptide hinge. PfCP-2.9 was highly immunogenic in animal studies, and antibodies elicited by the PfCP-2.9 highly inhibited parasite growth <it>in vitro</it>. This study focused on locating the distribution of epitopes on PfCP-2.9.</p> <p>Methods</p> <p>A panel of anti-PfCP-2.9 monoclonal antibodies (mAbs) were produced and their properties were examined by Western blot as well as <it>in vitro </it>growth inhibition assay (GIA). In addition, a series of PfCP-2.9 mutants containing single amino acid substitution were produced in <it>Pichia pastoris</it>. Interaction of the mAbs with the PfCP-2.9 mutants was measured by both Western blot and enzyme-linked immunosorbent assay (ELISA).</p> <p>Results</p> <p>Twelve mAbs recognizing PfCP-2.9 chimeric protein were produced. Of them, eight mAbs recognized conformational epitopes and six mAbs showed various levels of inhibitory activities on parasite growth <it>in vitro</it>. In addition, seventeen PfCP-2.9 mutants with single amino acid substitution were produced in <it>Pichia pastoris </it>for interaction with mAbs. Reduced binding of an inhibitory mAb (mAb7G), was observed in three mutants including M62 (Phe⁴⁹¹→Ala), M82 (Glu⁵¹¹→Gln) and M84 (Arg⁵¹³→Lys), suggesting that these amino acid substitutions are critical to the epitope corresponding to mAb7G. The binding of two non-inhibitory mAbs (mAbG11.12 and mAbW9.10) was also reduced in the mutants of either M62 or M82. The substitution of Leu³¹to Arg resulted in completely abolishing the binding of mAb1E1 (a blocking antibody) to M176 mutant, suggesting that the Leu residue at this position plays a crucial role in the formation of the epitope. In addition, the Asn¹⁵residue may also play an important role in the global folding of PfCP-2.9, as its substitution by Arg lead to reduced binding of most mAbs and abolishing the binding of mAb6G and mAbP5-W12.</p> <p>Conclusions</p> <p>This study provided valuable information on epitopes of PfCP-2.9 vaccine candidate through generation of a panel of mAbs and a series of PfCP-2.9 mutants. The information may prove to be useful for designing more effective malaria vaccines against blood-stage parasites.</p

Deformed Microcavity Quantum Cascade Lasers with Directional Emission

We report the experimental realization of deformed microcavity quantum cascade lasers (QCLs) with a Limaçon-shaped chaotic resonator. Directional light emission with a beam divergence of $\theta_{\|} \approx 33^{\circ}$ from QCLs emitting at λ ≈ 10µm was obtained in the plane of the cavity for deformations in the range 0.37 < ε < 0.43. An excellent agreement between measured and calculated far-field profiles was found. Both simulations and experiments show that the Limaçon-shaped microcavity preserves whispering gallery-like modes with high Q-factors for low deformations (ε < 0.50). In addition, while the measured spectra show a transition from whispering gallery-like modes to a more complex mode structure at higher pumping currents, we observed ‘universal far-field behavior’ for different intracavity mode distributions in the Limaçon microcavity, which can be explained by the distribution of unstable manifolds in ray optics simulations. Furthermore, the performance of the deformed microcavity lasers is robust with respect to variations of the deformation near its optimum value ε = 0.40, which implies that this structure reduces the requirements on photolithography fabrication. The successful realization of these microcavity lasers may lead to applications in optoelectronics.Engineering and Applied Science

Genome-wide association mapping for yield-related traits in soybean (Glycine max) under well-watered and drought-stressed conditions

Soybean (Glycine max) productivity is significantly reduced by drought stress. Breeders are aiming to improve soybean grain yields both under well-watered (WW) and drought-stressed (DS) conditions, however, little is known about the genetic architecture of yield-related traits. Here, a panel of 188 soybean germplasm was used in a genome wide association study (GWAS) to identify single nucleotide polymorphism (SNP) markers linked to yield-related traits including pod number per plant (PN), biomass per plant (BM) and seed weight per plant (SW). The SLAF-seq genotyping was conducted on the population and three phenotype traits were examined in WW and DS conditions in four environments. Based on best linear unbiased prediction (BLUP) data and individual environmental analyses, 39 SNPs were significantly associated with three soybean traits under two conditions, which were tagged to 26 genomic regions by linkage disequilibrium (LD) analysis. Of these, six QTLs qPN-WW19.1, qPN-DS8.8, qBM-WW1, qBM-DS17.4, qSW-WW4 and qSW-DS8 were identified controlling PN, BM and SW of soybean. There were larger proportions of favorable haplotypes for locus qPN-WW19.1 and qSW-WW4 rather than qBM-WW1, qBM-DS17.4, qPN-DS8.8 and qSW-DS8 in both landraces and improved cultivars. In addition, several putative candidate genes such as Glyma.19G211300, Glyma.17G057100 and Glyma.04G124800, encoding E3 ubiquitin-protein ligase BAH1, WRKY transcription factor 11 and protein zinc induced facilitator-like 1, respectively, were predicted. We propose that the further exploration of these locus will facilitate accelerating breeding for high-yield soybean cultivars

Development of multifunctional unmanned aerial vehicles versus ground seeding and outplanting: What is more effective for improving the growth and quality of rice culture?

The agronomic processes are complex in rice production. The mechanization efficiency is low in seeding, fertilization, and pesticide application, which is labor-intensive and time-consuming. Currently, many kinds of research focus on the single operation of UAVs on rice, but there is a paucity of comprehensive applications for the whole process of seeding, fertilization, and pesticide application. Based on the previous research synthetically, a multifunctional unmanned aerial vehicle (mUAV) was designed for rice planting management based on the intelligent operation platform, which realized three functions of seeding, fertilizer spreading, and pesticide application on the same flight platform. Computational fluid dynamics (CFD) simulations were used for machine design. Field trials were used to measure operating parameters. Finally, a comparative experimental analysis of the whole process was conducted by comparing the cultivation patterns of mUAV seeding (T1) with mechanical rice direct seeder (T2), and mechanical rice transplanter (T3). The comprehensive benefit of different rice management processes was evaluated. The results showed that the downwash wind field of the mUAV fluctuated widely from 0 to 1.5 m, with the spreading height of 2.5 m, and the pesticide application height of 3 m, which meet the operational requirements. There was no significant difference in yield between T1, T2, and T3 test areas, while the differences in operational efficiency and input labor costs were large. In the sowing stage, T1 had obvious advantages since the working efficiency was 2.2 times higher than T2, and the labor cost was reduced by 68.5%. The advantages were more obvious compared to T3, the working efficiency was 4 times higher than in T3, and the labor cost was reduced by 82.5%. During the pesticide application, T1 still had an advantage, but it was not a significant increase in advantage relative to the seeding stage, in which operating efficiency increased by 1.3 times and labor costs were reduced by 25%. However, the fertilization of T1 was not advantageous due to load and other limitations. Compared to T2 and T3, operational efficiency was reduced by 80% and labor costs increased by 14.3%. It is hoped that this research will provide new equipment for rice cultivation patterns in different environments, while improving rice mechanization, reducing labor inputs, and lowering costs

Directional Emission and Universal Far-Field Behavior from Semiconductor Lasers with Limacon-Shaped Microcavity

We report experimental demonstration of directional light emission from limaçon-shaped microcavity semiconductor lasers. Quantum cascade lasers (QCLs) emitting at $\lambda \approx 10 \mu m$ are used as a model system. Both ray optics and wave simulations show that for deformations in the range $0.37< \epsilon <0.43$, these microcavities support high quality-factor whispering gallerylike modes while having a directional far-field profile with a beam divergence $\theta \approx 30°$ in the plane of the cavity. The measured far-field profiles are in good agreement with simulations. While the measured spectra show a transition from whispering gallerylike modes to a more complex mode structure at higher pumping currents, the far field is insensitive to the pumping current demonstrating the predicted “universal far-field behavior” of this class of chaotic resonators. Due to their relatively high quality factor, our microcavity lasers display reduced threshold current densities compared to conventional ridge lasers with millimeter-long cavities. The performance of the limaçon-shaped QCLs is robust with respect to variations of the deformation near its optimum value of $\epsilon = 0.40$.Engineering and Applied Science