4,548 research outputs found

    Early intervention screening involves more than “simple” screening

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    From the perspective of preventive medical discourse, early interventional screening is one of the most important ways to intervene with developmentally delayed children and an important service for children’s public health. This paper details an historical perspective of early developmental screening in the United States and reexamines the concepts of early screening in widespread use in children’s populations to expose undisclosed facts. These facts remind us that early developmental screening might not be totally based on children’s needs, but on both the government’s desires and political activities. As a result, a certain population was identified as subjects that required developmental screening resulting in very large numbers studies. Under these circumstances, developmental screening instruments were used in conjunction with pediatricians’ individualized appraisals. The approach to developmental surveillance was to expand from the children to the parents’ concern. The instrument not only legitimately recruited parents and facilitated parents’ surveillance of their children’s development, but was also was a platform for highlighting parent-child interactions. This discussion may help community health nurses further understand different perspectives of early interventional screening in practice

    Pneumocystis jiroveci Pneumonia in Patients with Non-Hodgkin's Lymphoma Receiving Chemotherapy Containing Rituximab

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    AbstractRituximab enhances treatment efficacy of B-lineage lymphoma by targeting CD20+ B-cells. Such target therapies may compromise the immune system and render patients susceptible to opportunistic infections. We report 2 cases of lymphoma complicated with Pneumocystis jiroveci (previously known as P. carinii) pneumonia (PCP) while being treated with rituximab-containing chemotherapy regimens. In both cases, PCP developed during the neutropenic period. With timely diagnosis and proper management, both were treated successfully. We searched the literature and found that such opportunistic infection occurred only infrequently in lymphoma patients, and it has not been reported in the large-scale clinical trials of rituximab. Such cases demonstrate the importance of taking PCP into diagnostic consideration in lymphoma patients receiving similar therapies

    The influence of the technical dimension, functional dimension, and tenant satisfaction on tenant loyalty: an analysis based on the theory of planned behavior

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    This study primarily explored the influence of the technical dimension, functional dimension, and tenant satisfaction on tenant loyalty. The theory of planned behavior served as the basis of this study, and the three aforementioned factors (the technical dimension, the functional dimension, and tenant satisfaction) were incorporated into a conceptual framework for tenant loyalty. Structural equation modeling (SEM) was employed for parameter estimation. The participants consisted of tenants residing in eight administrative districts in Kaohsiung City. 315 questionnaires were administered, all of which were returned. After removing 15 invalid responses, there were 300 valid responses, which indicated an effective recovery rate of 95.2%. The results showed that the technical dimension, the functional dimension, and attitude significantly and positively influenced tenant satisfaction. Tenant satisfaction, perceived behavioral control, and social norms significantly and positively influenced tenant loyalty. Tenant satisfaction mediated the influence of the technical dimension and the functional dimension on tenant loyalty; the mediating effect of the functional dimension on tenant loyalty was greater than that of the technical dimension. The findings of this study highlight the measures rental companies should adopt in order to enhance the technical dimension, functional dimension, and tenant satisfaction, as this is crucial to maintaining sustainable operations

    Extraction of single-trial cortical beta oscillatory activities in EEG signals using empirical mode decomposition

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    <p>Abstract</p> <p>Background</p> <p>Brain oscillatory activities are stochastic and non-linearly dynamic, due to their non-phase-locked nature and inter-trial variability. Non-phase-locked rhythmic signals can vary from trial-to-trial dependent upon variations in a subject's performance and state, which may be linked to fluctuations in expectation, attention, arousal, and task strategy. Therefore, a method that permits the extraction of the oscillatory signal on a single-trial basis is important for the study of subtle brain dynamics, which can be used as probes to study neurophysiology in normal brain and pathophysiology in the diseased.</p> <p>Methods</p> <p>This paper presents an empirical mode decomposition (EMD)-based spatiotemporal approach to extract neural oscillatory activities from multi-channel electroencephalograph (EEG) data. The efficacy of this approach manifests in extracting single-trial post-movement beta activities when performing a right index-finger lifting task. In each single trial, an EEG epoch recorded at the channel of interest (CI) was first separated into a number of intrinsic mode functions (IMFs). Sensorimotor-related oscillatory activities were reconstructed from sensorimotor-related IMFs chosen by a spatial map matching process. Post-movement beta activities were acquired by band-pass filtering the sensorimotor-related oscillatory activities within a trial-specific beta band. Signal envelopes of post-movement beta activities were detected using amplitude modulation (AM) method to obtain post-movement beta event-related synchronization (PM-bERS). The maximum amplitude in the PM-bERS within the post-movement period was subtracted by the mean amplitude of the reference period to find the single-trial beta rebound (BR).</p> <p>Results</p> <p>The results showed single-trial BRs computed by the current method were significantly higher than those obtained from conventional average method (<it>P </it>< 0.01; matched-pair Wilcoxon test). The proposed method provides high signal-to-noise ratio (SNR) through an EMD-based decomposition and reconstruction process, which enables event-related oscillatory activities to be examined on a single-trial basis.</p> <p>Conclusions</p> <p>The EMD-based method is effective for artefact removal and extracting reliable neural features of non-phase-locked oscillatory activities in multi-channel EEG data. The high extraction rate of the proposed method enables the trial-by-trial variability of oscillatory activities can be examined, which provide a possibility for future profound study of subtle brain dynamics.</p

    Improving Efficiency of Evaporated Cu 2

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    Consecutive Tumor Lysis Syndrome and Hepatic Failure after Transarterial Chemoembolization for Treatment of Hepatocellular Aarcinoma: A Case Report and Literature Review

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    Introduction: Acute tumor lysis syndrome (ATLS) and hepatic failure are fatal complications that can occur in patients with hepatocellular carcinoma (HCC) who undergo transarterial chemoembolization (TACE).Presentation of Case: We report the case of a 78-year-old man with HCC who had successive ATLS and hepatic failure after the first course of TACE. He succumbed due to rapid deterioration of his condition.Conclusion: We therefore concluded that awareness of the risks of ATLS and hepatic failure before administration of TACE is crucial in patients with HCC
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