A speech envelope landmark for syllable encoding in human superior temporal gyrus.

The most salient acoustic features in speech are the modulations in its intensity, captured by the amplitude envelope. Perceptually, the envelope is necessary for speech comprehension. Yet, the neural computations that represent the envelope and their linguistic implications are heavily debated. We used high-density intracranial recordings, while participants listened to speech, to determine how the envelope is represented in human speech cortical areas on the superior temporal gyrus (STG). We found that a well-defined zone in middle STG detects acoustic onset edges (local maxima in the envelope rate of change). Acoustic analyses demonstrated that timing of acoustic onset edges cues syllabic nucleus onsets, while their slope cues syllabic stress. Synthesized amplitude-modulated tone stimuli showed that steeper slopes elicited greater responses, confirming cortical encoding of amplitude change, not absolute amplitude. Overall, STG encoding of the timing and magnitude of acoustic onset edges underlies the perception of speech temporal structure

Cost-Effectiveness of Advanced Imaging Technologies in the Presurgical Workup of Epilepsy.

The cost-effectiveness and benefit of many diagnostic tests used in the presurgical evaluation for persons with epilepsy is for the most part uncertain as is their influence on decision-making. The options we have at our disposal are ever increasing. Advanced imaging modalities aim to improve surgical candidacy by helping us better define the epileptogenic zone and optimize surgical planning. However, judicious use is important. Randomized controlled trials delineating which mode of investigation is superior are lacking. Presurgical tests do have incremental value by increasing surgical candidacy and refining surgical planning. The yield of additional imaging will increase with complex localization. However, every case must be tailored by hypothesis, cost, and accessibility. Future studies using a quantitative cost-benefit framework are needed to determine the cost-effectiveness of advanced diagnostic tests (beyond magnetic resonance imaging) in the presurgical evaluation of those with epilepsy

A Review of Regional Economic Models for Fisheries Management in the U.S.

In 1986, Andrews and Rossi reviewed input-output (IO)studies of U.S. fisheries. Since then, many more fisheries studies have appeared using IO and other types of regional economic models, such as Fishery Economic Assessment Models, Social Accounting Matrices, and Computable General Equilibrium models. However, to our knowledge no updated summary of these studies or models has appeared since 1986. This paper attempts to fill this gap by briefly reviewing the types of regional economic models that have been applied to fisheries, reviewing studies using these models that have been conducted for U.S. fisheries, and identifying data and modeling issues associated with regional economic analysis of fisheries in the U.S. The authors conclude that although economic impact analysis of fisheries policy is required under federal law, development of more representative regional economic models for this purpose is not likely to be forthcoming without increased information obtained through some type of comprehensive data collection program.Review, regional economic models, fisheries, IO, FEAM, SAM, CGE, IMPLAN, data., Community/Rural/Urban Development, Resource /Energy Economics and Policy, R1, R13, R15,

TRANDESNF: A computer program for transonic airfoil design and analysis in nonuniform flow

The use of a transonic airfoil code for analysis, inverse design, and direct optimization of an airfoil immersed in propfan slipstream is described. A summary of the theoretical method, program capabilities, input format, output variables, and program execution are described. Input data of sample test cases and the corresponding output are given