15,103 research outputs found

    Frobenius morphisms and stability conditions

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    We generalize Deng-Du's folding argument, for the bounded derived category D(Q)\mathcal{D}(Q) of an acyclic quiver QQ, to the finite dimensional derived category D(ΓQ)\mathcal{D}(\Gamma Q) of the Ginzburg algebra ΓQ\Gamma Q associated to QQ. We show that the FF-stable category of D(ΓQ)\mathcal{D}(\Gamma Q) is equivalent to the finite dimensional derived category D(ΓS)\mathcal{D}(\Gamma\mathbb{S}) of the Ginzburg algebra ΓS\Gamma\mathbb{S} associated to the species S\mathbb{S}, which is folded from QQ. If (Q,S)(Q,\mathbb{S}) is of Dynkin type, we prove that StabD(S)\operatorname{Stab}\mathcal{D}(\mathbb{S}) (resp. the principal component StabD(ΓS)\operatorname{Stab}^\circ\mathcal{D}(\Gamma\mathbb{S})) of the space of the stability conditions of D(S)\mathcal{D}(\mathbb{S}) (resp. D(ΓS)\mathcal{D}(\Gamma\mathbb{S})) is canonically isomorphic to FStabD(Q)\operatorname{FStab}\mathcal{D}(Q) (resp. the principal component FStabD(ΓQ)\operatorname{FStab}^\circ\mathcal{D}(\Gamma Q)) of the space of FF-stable stability conditions of D(Q)\mathcal{D}(Q) (resp. D(ΓQ)\mathcal{D}(\Gamma Q)). There are two applications. One is for the space NStabD(ΓQ)\operatorname{NStab}\mathcal{D}(\Gamma Q) of numerical stability conditions in StabD(ΓQ)\operatorname{Stab}^\circ\mathcal{D}(\Gamma Q). We show that NStabD(ΓQ)\operatorname{NStab}\mathcal{D}(\Gamma Q) consists of BrQ/BrS\operatorname{Br} Q/\operatorname{Br} \mathbb{S} many connected components, each of which is isomorphic to StabD(ΓS)\operatorname{Stab}^\circ\mathcal{D}(\Gamma\mathbb{S}), for (Q,S)(Q,\mathbb{S}) is of type (A3,B2)(A_3, B_2) or (D4,G2)(D_4, G_2). The other is that we relate the FF-stable stability conditions to the Gepner type stability conditions.Comment: Update versio

    Benefit Evaluation of the Country of Origin Labeling in Taiwan: Results from Auction Experiment

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    This research is aimed at investigating the consumer’s preference for food produced in Taiwan and the economic benefits for the country of origin labeling. The study uses both experimental auction and contingent valuation method (CVM) to investigate factors that affect the consumer’s willingness to pay (WTP) for products under country-of-origin labeling (COOL). Experimental auctions of Taiwan and China preserved olives as well as Taiwan, China and Vietnam oolong teas were conducted using the Vickrey’s second price sealed bid auction. For CVM, the study used the double-bounded dichotomous choice method in which we started assuming the same base price for all products in the first question and then varied the prices in the second CV question. The products not chosen in the first question were offered with a discount in a range from 10% to 50% in the following question. Based on auction data, the Tobit model shows that the estimated premiums are 58.1%, 78.15% and 98.13% for Taiwan products over their alternatives of China olives, China oolong tea, and Vietnam oolong tea, respectively. Based on the CVM, the estimated premiums for Taiwan over China olives from a Logit model is 67%, and the premiums for Taiwan produced oolong tea should lie between 50% to an unknown upper bound over China and Vietnam alternatives as the Multinomial Logit model cannot be successfully estimated due to too few choice switches with discounted prices. The study thus demonstrates the superiority of the experimental auction over the CVM in eliciting the WTP for foods produced in Taiwan. The study concludes that enacting a COOL law would increase economic benefits to consumers in Taiwan, and at the same time, placing the imported products in the level playing field.country-of-origin labeling, experimental auction, Tobit model, contingent valuation method, logit model, multinomial logit model, willingness to pay, Agricultural and Food Policy, Consumer/Household Economics, Demand and Price Analysis, Food Consumption/Nutrition/Food Safety, Q13, D12.,

    Building an Effective Learning Environment for Chinese Language Learners

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    This portfolio is a compilation of papers that the author originally wrote during her study in the program of Master of Second Language Teaching at Utah State University. While pursuing the Master’s degree, the author also served as an instructor, teaching assistant, and research assistant in the Chinese program. Thus, this work is framed by the author\u27s personal reflection accumulated from her day-to-day teaching experiences and class observations. The portfolio consists of three major sections: (1) teaching perspectives, (2) research perspectives, and (3) an annotated bibliography. With the aim to identify the elements of an effective and communicative learning environment for Chinese language learners in a foreign setting, the author analyzes both the facilitating parameters in an at-home learning environment and the study abroad context. The author also explores the topics of Digital Story Telling and teaching pragmatics. This portfolio is intended to benefit teachers of the Chinese language and culture that seek to build a fruitful learning environment in their classrooms around the world

    Network monitoring in multicast networks using network coding

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    In this paper we show how information contained in robust network codes can be used for passive inference of possible locations of link failures or losses in a network. For distributed randomized network coding, we bound the probability of being able to distinguish among a given set of failure events, and give some experimental results for one and two link failures in randomly generated networks. We also bound the required field size and complexity for designing a robust network code that distinguishes among a given set of failure events

    A Bayesian measurement error model for two-channel cell-based RNAi data with replicates

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    RNA interference (RNAi) is an endogenous cellular process in which small double-stranded RNAs lead to the destruction of mRNAs with complementary nucleoside sequence. With the production of RNAi libraries, large-scale RNAi screening in human cells can be conducted to identify unknown genes involved in a biological pathway. One challenge researchers face is how to deal with the multiple testing issue and the related false positive rate (FDR) and false negative rate (FNR). This paper proposes a Bayesian hierarchical measurement error model for the analysis of data from a two-channel RNAi high-throughput experiment with replicates, in which both the activity of a particular biological pathway and cell viability are monitored and the goal is to identify short hair-pin RNAs (shRNAs) that affect the pathway activity without affecting cell activity. Simulation studies demonstrate the flexibility and robustness of the Bayesian method and the benefits of having replicates in the experiment. This method is illustrated through analyzing the data from a RNAi high-throughput screening that searches for cellular factors affecting HCV replication without affecting cell viability; comparisons of the results from this HCV study and some of those reported in the literature are included.Comment: Published in at http://dx.doi.org/10.1214/11-AOAS496 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

    An Indirubin Derivative, Indirubin-39-MonoximeSuppresses Oral Cancer Tumorigenesis through theDownregulation of Survivin

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    Oral cancer is the fourth most common cause of death from cancer in Taiwanese men. Indirubin-3′-monoxime (I3M), a potent cyclin-dependent kinase inhibitor, has therapeutic effects in other cancer cells. In this study, we carried out in vitro assays to test cell viability, cell cycle progression, apoptosis, cell migration and invasion in this cancer type. In addition, using an oral tumorigenic animal model, we examined target gene and protein expression using real time qPCR, immunoblotting and immunohistochemical staining. Our results demonstrate that I3M has an anti-proliferative effect in both Cal-27 and HSC-3 oral cancer cell lines and that treatment of Cal-27 and HSC-3 cells with I3M results in apoptosis through the activation of cytochrome c. In addition, I3M interrupts the cell cycle in Cal-27 cells in a dose-dependent manner by arresting cells in the G2/M phase. We also found that I3M suppresses migration and invasion in Cal-27 cells by inhibiting the expression of focal adhesion kinase, urokinase-type plasminogen inhibitor, and matrix metalloproteinase 9. Moreover, we identified survivin as a target protein in I3M-treated oral cancer cells. Using an oral cancer mouse model, we demonstrate that topical application of an adhesive gel composed of I3M and poly(vinyl alcohol) (I3M/PVA) has dose-dependent anti-tumorigenic effects. Following treatment, the expression of survivin protein and mRNA was downregulated in cancerous tissues. Furthermore, plasma survivin levels were also reduced in the I3M-treated mice. These results suggest that topical application of I3M, a drug synthesized from indirubin, which is found in Qing-Dai – has therapeutic potential for treating oral cancer

    Examining Stakeholder Perspectives: Process, Performance and Progress of the Age-Friendly Taiwan Program.

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    Since Taiwans age-friendly city (AFC) program was launched in 2012, the central government has provided various resources to the countrys 22 local authorities, including budgetary support, policy advocacy, and consultation from a team of experts. This study examines stakeholder perspectives on the process, performance, and outcome of the AFC program. A 53-item questionnaire was developed based on the World Health Organization (WHO) guideline, including mechanisms and processes (20 items), outcome evaluations (23 items), and resource integration (10 items). There was a great difference found among scores between facilitators and experts for inter-exchange experience with local and international cities (40%) and monitor and revise indicators (37%) in mechanisms and processes, evaluate performance of indicators and action plans (37%) in outcome evaluations, and interaction between government and community (46%) and interaction between civil organization and senior society (39%) in resource integration. Clearly, facilitators showed overly optimistic assessments in AFC mechanisms and processes, outcome evaluation, and resource integration. The results showed disconnect between experts expectations versus actual practice conducted by facilitators. Implications of these findings are to integrate top down expectations with the realities of bottom up practice to design more realistic evaluations; continue to educate stakeholders about design, implementation and evaluation; and further integrate resources from government, civil organizations, and community
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