Joint Spectrum Sensing and Resource Allocation for OFDM-based Transmission with a Cognitive Relay

In this paper, we investigate the joint spectrum sensing and resource allocation problem to maximize throughput capacity of an OFDM-based cognitive radio link with a cognitive relay. By applying a cognitive relay that uses decode and forward (D&F), we achieve more reliable communications, generating less interference (by needing less transmit power) and more diversity gain. In order to account for imperfections in spectrum sensing, the proposed schemes jointly modify energy detector thresholds and allocates transmit powers to all cognitive radio (CR) subcarriers, while simultaneously assigning subcarrier pairs for secondary users (SU) and the cognitive relay. This problem is cast as a constrained optimization problem with constraints on (1) interference introduced by the SU and the cognitive relay to the PUs; (2) miss-detection and false alarm probabilities and (3) subcarrier pairing for transmission on the SU transmitter and the cognitive relay and (4) minimum Quality of Service (QoS) for each CR subcarrier. We propose one optimal and two sub-optimal schemes all of which are compared to other schemes in the literature. Simulation results show that the proposed schemes achieve significantly higher throughput than other schemes in the literature for different relay situations.Comment: EAI Endorsed Transactions on Wireless Spectrum 14(1): e4 Published 13th Apr 201

Logarithmic Correction to BPS Black Hole Entropy from Supersymmetric Index at Finite Temperature

It has been argued by Iliesiu, Kologlu and Turiaci in arXiv:2107.09062 that one can compute the supersymmetric index of black holes using black hole geometry carrying finite temperature but a specific complex angular velocity. We follow their prescription to compute the logarithmic correction to the entropy of BPS states in four dimensions, defined as the log of the index of supersymmetric black holes, and find perfect agreement with the previous results for the same quantity computed using the near horizon $AdS_2 \times S^2$ geometry of zero temperature black holes. Besides giving an independent computation of supersymmetric black hole entropy, this analysis also provides a test of the procedure used previously for computing logarithmic corrections to Schwarzschild and other non-extremal black hole entropy.Comment: 23 page

Insilico Molecular Docking - A tool to understand the action of Rasaushadhis

Rasashastra, a branch of Ayurveda consists of many metallo-mineral preparations which are explained as highly efficacious in smaller doses and even in shorter duration. We know the functions of Rasaushadhis (herbo-mineral preparations), but we are lacking the knowledge of their Pharmacodynamics which may benefit us in understanding the exact site where, how and which active principle work and at what rate a drug will interact with its target biomolecule. The advent of new Sciences like Bioinformatics has made drug discovery faster and economical. Bioinformatics research focuses on biology at a molecular level by identifying the effect of drugs at the level of individual genes, DNA, RNA and proteins. It utilizes existing information to model disease pathways and identifies precise targets of the drug. The unclearly answered questions can be clarified by understanding and adopting the concept of ‘Insilico Molecular Docking’, means a computational study of binding of Ligand to specific Receptor. The action between the receptor and ligand is by selectivity and affinity; Lock and Key concept. It encompasses all theoretical methods and computational techniques to model and the behavior of molecules and by scoring function we can come to know the best suitable receptor for particular ligand. The working methodology includes preparation of Ligand, Receptor, Docking and inspection by X-Ray Crystallography, NMR techniques. The process of standardization is needed in Rasashastra but, there are some difficulties. One can overcome this by understanding the mode of action of Rasaushadhis -Rasabhasmas through molecular Docking which helps in drug discovery and development, optimisation of action and inhibition of harmful effects

Women's Participation in Cardiovascular Clinical Trials From 2010 to 2017

Background: Cardiovascular disease is the leading cause of death among women worldwide, yet, women have historically been underrepresented in cardiovascular trials. Methods: We systematically assessed the participation of women in completed cardiovascular trials registered in ClinicalTrials.gov between 2010 and 2017, and extracted publicly available information including disease type, sponsor type, country, trial size, intervention type, and the demographic characteristics of trial participants. We calculated the female-to-male ratio for each trial and determined the prevalence-adjusted estimates for participation of women by dividing the percentage of women among trial participants by the percentage of women in the disease population (participation prevalence ratio; a ratio of 0.8 to 1.2 suggests comparable prevalence and good representation). Results: We identified 740 completed cardiovascular trials including a total of 862 652 adults, of whom 38.2% were women. The median female-to-male ratio of each trial was 0.51 (25th quartile, 0.32; 75th quartile, 0.90) overall and varied by age group (1.02 in ≤55 year old group versus 0.40 in the 61- to 65-year-old group), type of intervention (0.44 for procedural trials versus 0.78 for lifestyle intervention trials), disease type (0.34 for acute coronary syndrome versus 3.20 for pulmonary hypertension), region (0.45 for Western Pacific versus 0.55 for the Americas), funding/sponsor type (0.14 for government-funded versus 0.73 for multiple sponsors), and trial size (0.56 for smaller [n≤47] versus 0.49 for larger [n≥399] trials). Relative to their prevalence in the disease population, participation prevalence ratio was higher than 0.8 for hypertension, pulmonary arterial hypertension and lower (participation prevalence ratio 0.48 to 0.78) for arrhythmia, coronary heart disease, acute coronary syndrome, and heart failure trials. The most recent time period (2013 to 2017) saw significant increases in participation prevalence ratios for stroke (P=0.007) and heart failure (P=0.01) trials compared with previous periods. Conclusions: Among cardiovascular trials in the current decade, men still predominate overall, but the representation of women varies with disease and trial characteristics, and has improved in stroke and heart failure trials

A Novel Speech Separation Based On Ica Strategical Classification

ABSTRACT: Monaural conversation splitting is a well-recognized process. Modern research utilize monitored classification methods to estimate the ideal binary cover up (IBM) inorder to address the issue. In a supervised learning structure, the issue of generalization to conditions different from those in coaching is most essential. This paper presents techniques that require only a little coaching corpus and can generalize to invisible circumstances. The program uses assistance vector machines to understand category hints and then runs on the rethresholding technique inorder to calculate the IBM. A submission fitting method is used to make generalizations to invisible signal-to-noise rate circumstances and voice action recognition centered variation isused to make generalizations to unseen noise circumstances. Methodical evaluation reveals that the recommended strategy generates top quality IBM estimates under invisible circumstances. Hence in this proposed method, a single channel speech enhancement algorithm is intend to offer by constructing a observational signal and noise signal for single channel speech noise reduction based on Independent component analysis (ICA),thereby noise and original speech can be separated through ICA. Hence Simulation results provides that much better peak signal to noise ratio(PSNR) and denoising effect can be procured by using this algorithm

OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation

2-Oxoglutarate (2OG) and Fe(II)-dependent oxygenase domain-containing protein 1 (OGFOD1) is predicted to be a conserved 2OG oxygenase, the catalytic domain of which is related to hypoxia-inducible factor prolyl hydroxylases. OGFOD1 homologs in yeast are implicated in diverse cellular functions ranging from oxygen-dependent regulation of sterol response genes (Ofd1, Schizosaccharomyces pombe) to translation termination/mRNA polyadenylation (Tpa1p, Saccharomyces cerevisiae). However, neither the biochemical activity of OGFOD1 nor the identity of its substrate has been defined. Here we show that OGFOD1 is a prolyl hydroxylase that catalyzes the posttranslational hydroxylation of a highly conserved residue (Pro-62) in the small ribosomal protein S23 (RPS23). Unusually OGFOD1 retained a high affinity for, and forms a stable complex with, the hydroxylated RPS23 substrate. Knockdown or inactivation of OGFOD1 caused a cell type-dependent induction of stress granules, translational arrest, and growth impairment in a manner complemented by wild-type but not inactive OGFOD1. The work identifies a human prolyl hydroxylase with a role in translational regulation

K-Space at TRECVID 2008

In this paper we describe K-Space’s participation in TRECVid 2008 in the interactive search task. For 2008 the K-Space group performed one of the largest interactive video information retrieval experiments conducted in a laboratory setting. We had three institutions participating in a multi-site multi-system experiment. In total 36 users participated, 12 each from Dublin City University (DCU, Ireland), University of Glasgow (GU, Scotland) and Centrum Wiskunde and Informatica (CWI, the Netherlands). Three user interfaces were developed, two from DCU which were also used in 2007 as well as an interface from GU. All interfaces leveraged the same search service. Using a latin squares arrangement, each user conducted 12 topics, leading in total to 6 runs per site, 18 in total. We officially submitted for evaluation 3 of these runs to NIST with an additional expert run using a 4th system. Our submitted runs performed around the median. In this paper we will present an overview of the search system utilized, the experimental setup and a preliminary analysis of our results

On the analytical formulation of excess noise in avalanche photodiodes with dead space

Simple, approximate formulas are developed to calculate the mean gain and excess noise factor for avalanche photodiodes using the dead-space multiplication theory in the regime of small multiplication width and high applied electric field. The accuracy of the approximation is investigated by comparing it to the exact numerical method using recursive coupled integral equations and it is found that it works for dead spaces up to 15% of the multiplication width, which is substantial. The approximation is also tested for real materials such as GaAs, InP and Si for various multiplication widths, and the results found are accurate within ∼ 15% of the actual noise, which is a significant improvement over the local-theory noise formula. The results obtained for the mean gain also confirm the recently reported relationship between experimentally determined local ionization coefficients and the enabled non-local ionization coefficients