Determination of pH dependent antioxidant activity of Palm (Borassus flabellifer) Polyphenol compounds by Photoluminol and DPPH methods -A Comparison redox-reaction Sensitivity

Palm juice (Borassus flabellifer) is one of the most common and cheap natural juices. Fermented palm juice contains various phytochemical compounds that exhibit antioxidant activity. In the present study, we examined the effects of pH on the production of phytochemicals and their antioxidant activity during the fermentation process. The concentration of total phenolics and flavonoid compounds of fermented palm juice and their antioxidant activity were investigated at various pH. The results showed that total phenolics concentration and antioxidant activity of palm wine and palm vinegar increase as pH increases: 3.54.55.5. Maximum flavonoid concentration was obtained at pH 6.5. Measurements of antioxidant activity by conventional DPPH method and Photochem antioxidant analyzer technique were highly correlated, with a corresponding R2 value of 0.94

PPAR Regulation of Inflammatory Signaling in CNS Diseases

Central nervous system (CNS) is an immune privileged site, nevertheless inflammation associates with many CNS diseases. Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that regulate immune and inflammatory responses. Specific ligands for PPARα, γ, and δ isoforms have proven effective in the animal models of multiple sclerosis (MS), Alzheimer's disease, Parkinson's disease, and trauma/stroke, suggesting their use in the treatment of neuroinflammatory diseases. The activation of NF-κB and Jak-Stat signaling pathways and secretion of inflammatory cytokines are critical in the pathogenesis of CNS diseases. Interestingly, PPAR agonists mitigate CNS disease by modulating inflammatory signaling network in immune cells. In this manuscript, we review the current knowledge on how PPARs regulate neuroinflammatory signaling networks in CNS diseases

Hybrid solar cell with TiO2 film: BBOT polymer and copper phthalocyanine as sensitizer

An organic-inorganic hybrid solar cell was fabricated using Titanium dioxide (TiO2): 2,5-bis(5-tert-butyl-2-benzoxazolyl) thiophene (BBOT) film and Copper Phthalocyanine (CuPc) as a sensitizer. BBOT was used in photodetector in other reported research works, but as per best of our knowledge, it was not implemented in solar cells till date. The blend of TiO2: BBOT blend was used to fabricate the film on ITO-coated glass and further a thin layer of CuPc was coated on the film. This was acted as photoanode and another ITO coated glass with a platinum coating was used as a counter electrode (cathode). An optimal blend of acetonitrile (solvent) (50-100%), 1,3-dimethylimidazolium iodide (10-25%), iodine (2.5-10%) and lithium iodide, pyridine derivative and thiocyanate was used as electrolytes in the hybrid solar cell. The different structural, optical and electrical characteristics were measured. The Hybrid solar cell showed a maximum conversion efficiency of 6.51%

Sustainable livestock production: A systematic review of different constraints associated with sustainable livestock production

Agriculture in general and ranches contribute significantly to the sustainability of poor and marginalized farmers. To meet the future requirements of an increasing population, animal productivity must be significantly increased. Animal production is increasingly influenced by a variety of external factors. This includes increasing demand for animal products and an inadequate supply of feed ingredients due to competition in natural resources and trade barriers. At the same time, there is growing concern about livestock and its health consequences. Optimization of the productivity and effectiveness within such restrictions, as well as profit maximization for all stakeholders, are important goals. Several indicators show that animal production optimization is still potentially possible. New science and technologies seem to offer many opportunities for innovation in animal production. Animal productivity improvement has significant mitigation effects in both developed and developing countries. However, the extent of its impact also depends on factors such as the genetic potential of the animal and the introduction of management techniques. Acceptance by consumers and society is an important success factor. In summary, sustainable livestock is very important in livestock. This overview focuses on various issues and restrictions associated with sustainable livestock production

Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

Hyperthermia inhibits DNA double-strand break (DSB) repair that utilizes homologous recombination (HR) pathway by a poorly defined mechanism(s); however, the mechanisms for this inhibition remain unclear. Here we report that hyperthermia decreases H4K16 acetylation (H4K16ac), an epigenetic modification essential for genome stability and transcription. Heat-induced reduction in H4K16ac was detected in humans

Nuclear Structure of \u3csup\u3e76\u3c/sup\u3eGe from Inelastic Neutron Scattering Measurements and Shell Model Calculations

The low-lying, low-spin levels of 76Ge were studied with the (n,n′γ) reaction. Gamma-ray excitation function measurements were performed at incident neutron energies from 1.6 to 3.7 MeV, and γ-ray angular distributions were measured at neutron energies of 3.0 and 3.5 MeV. From these measurements, level spins, level lifetimes, γ-ray intensities, and multipole mixing ratios were determined. No evidence for a number of previously placed levels was found. Below 3.3 MeV, many new levels were identified, and the level scheme was re-evaluated. The B(E2) values support low-lying band structure. The 2+ mixed-symmetry state has been identified for the first time. A comparison of the level characteristics with large-scale shell model calculations yielded excellent agreement

Level Lifetimes and the Structure of \u3csup\u3e134\u3c/sup\u3eXe from Inelastic Neutron Scattering

The level structure of 134Xe was studied with the inelastic neutron scattering reaction followed by γ-ray detection. A number of level lifetimes were determined for the first time with the Doppler-shift attenuation method and the low-lying excited states were characterized. From this new spectroscopic information, the third excited state, a 0+ level which had only been observed in a previous inelastic neutron scattering study, was verified. Reduced transition probabilities were calculated; comparisons were drawn with a vibrational description of the nucleus and found lacking. The 3− octupole phonon has been confirmed, and the complete negative-parity multiplet resulting from the ν(1h11/22d3/2) configuration has also been tentatively identified for the first time in the N = 80 isotones

0\u3csup\u3e+\u3c/sup\u3e States in \u3csup\u3e130,132\u3c/sup\u3eXe: A Search for E(5) Behavior

The level structures of 130,132Xe were studied with the inelastic neutron scattering reaction followed by γ-ray detection. Level lifetimes were measured using the Doppler-shift attenuation method and low-lying excited states in these nuclei were characterized. With a focus on the decay properties of the 0+ states, these nuclei were examined as representations of the E(5) critical-point symmetry

Collective Quadrupole Behavior in \u3csup\u3e106\u3c/sup\u3ePd

Excited states in 106Pd were studied with the (n,n′γ) reaction, and comprehensive information for excitations with spin ≤6ℏ was obtained. The data include level lifetimes in the femtosecond regime, spins and parities, transition multipolarities, and multipole mixing ratios, which allow the determination of reduced transition probabilities. The E2 decay strength to the low-lying states is mapped up to ≈2.4 MeV in excitation energy. The structures associated with quadrupole collectivity are elucidated and organized into bands