The effects of artistic and social activities during hemodialysis on the life quality, pain perception, anxiety status of the patients and intradialytic complications

Introduction: We aimed to investigate the effects of social and artistic activity support on quality of life, pain perception, and anxiety status in hemodialysis (HD) patients and the relation between occupational therapy and frequent complications of HD.Methods: Volunteer instructors trained 22 patients participated in this study for wood painting for 4 hours/day, 2-3 days a week for six months. The State-Trait Anxiety Inventory (STAI I and STAI II) and Visual Analog Scale were applied before the social activity and at the 6th month. The quality of life evaluated with Short Form-36.Results: The patients who participated in the social activity more than 25 hours formed the study group (n=9), and those participated less than 25 hours made control group (n=13). There were significant differences in initial and 6th month values in both STAI I and STAI II scores of the study group, and only in STAI II score in the control group (p=0.008, p=0.015, p=0.003, respectively). In the study group, while STAI I and II mean was 49.9 and 52.8 in the first month, respectively, it decreased to 30.0 and 38.8 in 6th month, respectively. In the control group, in the first month mean of STAI II score was 56.9 and it decreased to 45.3 in the sixth month. The mean of physical function capacity from SF-36 parameters increased from 73.9 to 84.4 (p=0.026) in the study group and from 47.7 to 75.8 (p=0.002) in the control group. The difference between study and control group was statistically significant (p = 0.029). Conclusions: Our results support that social and artistic activities during HD have positive effects on chronic HD patients in terms of physical functioning level

Hemodiyaliz sırasında gerçekleştirilen sanatsal ve sosyal faaliyetlerin hastaların yaşam kalitesi, ağrı, kaygı durumları ve intradiyalitik komplikasyonlar üzerindeki etkileri

Introduction: We aimed to investigate the effects of social and artistic activity support on quality of life, pain perception, and anxiety status in hemodialysis (HD) patients and the relation between occupational therapy and frequent complications of HD.Methods: Volunteer instructors trained 22 patients participated in this study for wood painting for 4 hours/day, 2-3 days a week for six months. The State-Trait Anxiety Inventory (STAI I and STAI II) and Visual Analog Scale were applied before the social activity and at the 6th month. The quality of life evaluated with Short Form-36.Results: The patients who participated in the social activity more than 25 hours formed the study group (n=9), and those participated less than 25 hours made control group (n=13). There were significant differences in initial and 6th month values in both STAI I and STAI II scores of the study group, and only in STAI II score in the control group (p=0.008, p=0.015, p=0.003, respectively). In the study group, while STAI I and II mean was 49.9 and 52.8 in the first month, respectively, it decreased to 30.0 and 38.8 in 6th month, respectively. In the control group, in the first month mean of STAI II score was 56.9 and it decreased to 45.3 in the sixth month. The mean of physical function capacity from SF-36 parameters increased from 73.9 to 84.4 (p=0.026) in the study group and from 47.7 to 75.8 (p=0.002) in the control group. The difference between study and control group was statistically significant (p = 0.029). Conclusions: Our results support that social and artistic activities during HD have positive effects on chronic HD patients in terms of physical functioning level

Is there a relation between mean platelet volume and chronic kidney disease stages in diabetic patients?

WOS: 000371356600042Objective: Chronic kidney disesase (CKD) is a state of atherosclerotic and chronic inflammation and as the estimated glomerular filtration rate (GFR) declines, cardiovascular disease (CVD) risk and inflammation increase. Mean platelet volume (MPV) has shown to be influenced by cardiovascular risk factors. The aim of this study was to evaluate the relationship between MPV and CKD. Methods: This is prospective study of a total of 812 CKD patients. Patients with CKD were assigned to into the five groups depending on estimated GFR which were calculated by Modification of Diet in Renal Disease (MDRD). Patients demographics, comorbid disease were recorded, and laboratory variables were also evaluated. Results: The mean age of CKD patients was 62.6 +/- 15.4 years. According to stages, 96 patients (11.8%) were classified as stage 1 (GFR >90 ml/min/1.73 m(2)), 77 patients (9.5%) as stage 2 (GFR 89-60 ml/min/1.73 m(2)), 306 patients (37.7%) as stage 3 (GFR 59-30 ml/min/1.73 m(2)), 198 (24.4%) patients as stage 4 (GFR 29-15 ml/min/1.73 m(2)) and 135 (16.6%) patients as stage 5 (GFR < 15 ml/min/1.73 m(2), dialysis and non-dialysis). DM was found to be positive in 299 (152 female; 147 male) patients. The mean MPV was found to higher in diabetic patients compared to non-diabetic patients (9.5 +/- 1.3 fL vs 9.3 +/- 1.4 fL, p: 0.024). There was a positive correlation between CKD stage and MPV in diabetic male patients. Conclusion: The results of our study might suggest that diabetic male patients with CKD have higher MPV values support the idea that these groups have additional risks other than CKD and these patients should be followed closely in respect to its complications

Fabry Disease Prevalence in Renal Replacement Therapy in Turkey

Background: Fabry disease (FD) is an X-linked lysosomal storage disorder resulting from lack of alpha-galactosidase A (AGALA) activity in lysosomes. Objective: In this multicenter study, we aimed to evaluate the prevalence of FD in renal transplant (Tx) recipients in Turkey. We also screened dialysis patients as a control group. Methods: All Tx and dialysis patients were screened regardless of the presence of a primary disease. We measured the AGALA activity in all male patients as initial analysis. Mutation analysis was performed in male patients with decreased AGALA activity and in female patients as the initial diagnostic assay. Results: We screened 5,657 patients. A total of 17 mutations were identified. No significant difference was observed between the groups regarding the prevalence of patients with mutation. We found FD even in patients with presumed primary kidney diseases. Seventy-one relatives were analyzed and mutation was detected in 43 of them. We detected a patient with a new, unknown mutation (p.Cys223) in the GLA gene. Conclusions: There are important implications of the screening. First, detection of the undiagnosed patients leads to starting appropriate therapies for these patients. Second, the transmission of the disease to future generations may be prevented by prenatal screening after appropriate genetic counseling. In conclusion, we suggest screening of kidney Tx candidates for FD, regardless of etiologies of chronic kidney disease. (C) 2019 S. Karger AG, Base