98 research outputs found

    Advances in dermoscopy for detecting melanocytic lesions

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    Over the last 30 years dermatological approaches to diagnosis and management of melanocytic lesions have been revolutionized by the introduction of dermoscopy. Continuous improvements are being made in applying the technique, mostly in melanoma diagnosis, follow-up of melanocytic lesions and nevogenesis. Identification of new dermoscopic criteria, such as the dermoscopic island and the blue-black color for thin and nodular melanoma, respectively, further add two new weapons in the dermoscopical armamentarium for diagnosis of otherwise featureless melanoma. Recent advances show that short-term, 3-month, follow-up is the optimum time interval to identify minimal changes in initially featureless melanomas. Nevertheless, long-term follow-up is still useful for the recognition of changes in melanomas with a very low-rate of growth. Dermoscopy greatly improves diagnosis and early excision of melanomas and reduces the number of unnecessary excisions

    New insights in the pathogenesis and genetics of leprosy

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    In the last 30 years the leprosy burden has been dramatically reduced but over the last 5 years still more than 200,000 new cases were detected each year. Advances in immunology, pathogenesis, and genetics of leprosy have been reported. A deeper understanding of the mechanisms of infection will ultimately improve our ability to fight against this potentially devastating infectious disease

    Effects of a Chemical Sunscreen on UV-Induced Changes of Different Histological Features in Melanocytic Nevi

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    Several studies have investigated the effect of UV radiation on melanocytic nevi by using different approaches and different sources and types of irradiation.1 We read with interest the work of Carrera et al,2 and we would like to describe our experience also

    Two cases of granuloma faciale showing rosettes

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    Granuloma faciale (GF) is a rare benign chronic inflammatory dermatosis often difficult to distinguish clinically from other diseases, both inflammatory and neoplastic. Dermoscopy can be a helpful diagnostic tool and indeed several dermoscopic criteria observed in GF have been described in literature. We present two patients affected by GF in which we have observed rosettes

    Skin manifestations in patients with coronavirus disease 2019

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    Purpose of review: Coronavirus disease 2019 (COVID-19) is a well established respiratory tract illness. Recent studies in adults and children have shown an increasing number of patients reporting polymorphic cutaneous manifestations during COVID-19, including different types of rashes, from maculopapular, vascular, vesicular to atypical forms. Recent findings: Although pathogenesis of skin manifestations is still not fully understood, it has been proposed that cutaneous involvement during COVID-19 may be the results of the activation of the immune response against severe acute respiratory syndrome coronavirus-2, the reactivation or co-infection of herpesviruses or drug hypersensitivity. Summary: According to available literature, skin manifestations in patients with COVID-19 may be categorized on the basis of their clinical presentations as follows: erythematous rashes, lesions of vascular origin, vesicular rash, urticarial rash and acute generalized exanthematous pustulosis (AGEP), erythema multiforme and other polymorphic erythema/atypical reactions. Prompt recognition of these cutaneous manifestations represents a crucial point to facilitate diagnosis and management of COVID-19 patients

    A case of Angiomatoid Spitz Nevus in the elderly, with clinical and dermoscopic features

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    This case was presented at the on-line telepathology meeting on the ADOI platform held on October 19th 2022 by Dr Luongo

    Illumination system in visible light with variable solar-divergence for the solar orbiter METIS coronagraph

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    The measurement of the stray-rejection capabilities of METIS is part of the acceptance package of the instrument. The Illumination System in Visible Light (ISVL) has been developed to allow the stray-light rejection measurement down to 1x10-9 and under different operating conditions. The main characteristics of ISVL are outlined and discussed; the activities for the integration and verification of ISVL included the absolute radiometric characterization of the facility, including radiance measurement and radiance spatial and angular distribution. The procedures used to measure the performances of the facility are discussed and the obtained results illustrated
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