940 research outputs found

    Benign Neural Sheath Tumours of Major Nerves: Characteristics in119 Surgical Cases

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    Peripheral benign nerve sheath tumours are infrequent tumours and affect major nerve trunks. Some authors have indicated a high and prohibitive incidence of neurological injury in resection of these lesions. The authors describe their findings in a retrospective study comprising 119 patients with spontaneous benign nerve sheath tumours of the peripheral nervous system. Seventy-three patients had a schwannoma, 41 had neurofibroma and 5 had plexiform neurofibroma; 25 of the 119 patients suffered from neurofibromatosis. All schwannomas were excised completely and the outcome of patients was 41.0% improved, 6.8% worsened, 52.0% unchanged. Twenty-eight neurofibromas were excised completely and 13 subtotally; the outcome for patients was 19.5% improved, 19.5% worsened and 61% unchanged. All plexiform neurofibromas were removed subtotally and the outcome for patients was 20% improved and 80% unchanged. The best surgical results at average follow-up of 6 years were observed in the patients with schwannoma, the worst in those with plexiform neurofibroma. Our results demonstrated that it is often possible to remove schwannomas as well as neurofibromas with an acceptable risk of injury to the nerve

    Analysis of the interaction of calcitriol with the disulfide isomerase ERp57

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    Calcitriol, the active form of vitamin D3, can regulate the gene expression through the binding to the nuclear receptor VDR, but it can also display nongenomic actions, acting through a membrane- associated receptor, which has been discovered as the disul de isomerase ERp57. The aim of our research is to identify the binding sites for calcitriol in ERp57 and to analyze their interaction. We rst studied the interaction through bioinformatics and uorimetric analyses. Subsequently, we focused on two protein mutants containing the predicted interaction domains with calcitriol: abb’- ERp57, containing the rst three domains, and a’-ERp57, the fourth domain only. To consolidate the achievements we used the calorimetric approach to the whole protein and its mutants. Our results allow us to hypothesize that the interaction with the a’ domain contributes to a greater extent than the other potential binding sites to the dissociation constant, calculated as a Kd of about 10−9 M

    Baudelaire et la « haine du végétal »

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    Dans les premières lignes d’Anywhere out of the world, Baudelaire prête aux habitants de Lisbonne la « haine du végétal ». Cet article se propose d’éclairer le sens de cette formule d’un point de vue historique, esthétique et polémique, en se fondant sur l’œuvre et la correspondance de Baudelaire, ainsi que sur l’intertexte romantique (Théophile Gautier, Pétrus Borel)

    Gautier et Nerval. Collaborations, solidarités, différences, textes réunis par Anne Geisler-Szmulewicz et Sarga Moussa

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    Les affinités entre Gautier et Nerval ont fait l’objet d’une trentaine de travaux, pour la plupart des articles. Le «Dossier» du «Bulletin de la Société Théophile Gautier» numéro 38 est la première entreprise de réflexion collective sur ce sujet; il rassemble les actes d’une journée d’étude qui s’est tenue le 27 novembre 2015 à la Maison de Balzac, à l’initiative de la Société Théophile Gautier. Il comprend sept articles, qui sont autant de mises au point érudites et attentives aux subtilités..

    Bifid median nerve: report of two cases

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    The median nerve divides into its terminal branches at or proximal to the distal edge of the flexor retinaculum. An anatomy of the median nerve within the carpal tunnel is reported in two separate cases. Emphasis has been given to the value of direct vision when incising the flexor retinaculum in order to avoid injure of the median nerve

    Maximising Confidence: A Grounded Theory on Student Engagement to Speak (SEtS) in a language class.

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    Learning to speak a second language is a challenging experience for the majority of language learners. "Your whole person is affected as you struggle to reach beyond the confines of your first language and into a new language, a new culture, a new way of thinking, feeling and acting" (H. D. Brown, 2000, p. 12). Thus, teaching to speak a foreign language is also a defying undertaking where, if we want students to use the language in class realistically and autonomously, speaking class activities need to be 'productive, purposeful, interactive, challenging, safe and authentic' (Thornbury 2007: 90). That said, there is a widespread assertion amongst language teachers that in class "students do not talk at all" (Bahrani & Soltani, 2012. p. 26). Within that context, this study investigates the factors affecting student engagement to speak (SEtS) in a language class, which is an unexplored concept - from the students' perspective - linked to the fields of Student Engagement (SE), Willingness to Communicate (WTC) and Communicative Language Teaching (CLT). A mixed methods approach was used to obtain the data, including a focus group, student and teacher interviews, participant observation insights, self reflections and a survey. The data was analysed by using Grounded Theory (GT) strategies (Charmaz 2014; Glaser 2007; Pace 2012) within an analytic autoethnography (Anderson 2006) to search for an emergent theory that could explain what engages students to speak in a language class. The study is framed within a constructivist approach to data collection and analysis, and the research includes the participation of 388 Australian National University undergraduate students of French, Spanish, German and Italian at different levels of instruction, 14 teachers and the researcher's own voice, supplemented by the relevant literature. The journey is paved with quotes of students' and teachers' words and with self reflective ethnographic analytical memos. The findings, obtained through the process of coding, categorisation and theoretical development of the qualitative data, complemented by the quantitative results of the survey, are grounded on students' lived experiences as well as the researcher's. They suggest that SEtS is a socio affective process underpinned by three interdependent dimensions involving the teacher's personal qualities, the course content and the classroom environment. The students' level of connectedness to those three dimensions affects their self confidence and either engages or disengages them to speak in class. This study shows that what really matters to students is still the human condition underpinned by affective and behavioural components such as teacher-student relationships, motivation and anxiety, and it serves as a stepping stone for further research in the area of language pedagogy and SEtS, and particularly on the role the personality of a teacher may play in second language teaching and learning

    Primary spinal epidural non-Hodgkin's lymphomas: a clinical study

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    Estudio de las restricciones al diseño e implementación de proyectos de mecanismo de desarrollo limpio forestales en la Argentina

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    El cambio climático constituye un problema serio que afecta a toda la humanidad. En virtud de ello, surge el Protocolo de Kyoto de la Convención Marco de las Naciones Unidas como el mecanismo para coordinar los esfuerzos multilaterales para hacer frente a dicha problemática. Este acuerdo compromete legalmente a los países desarrollados a reducir sus emisiones en un nivel no menor a 5 por ciento en relación a los niveles de 1990 hasta finales de 2012. Además, esta meta de reducción puede ser apoyada por los países en vías de desarrollo, a través del mecanismo de desarrollo limpio (MDL)que incluye los proyectos de forestación y reforestación. Estos proyectos se consideraron por su notable importancia en la regulación climática; pero su evolución se ha visto condicionada por una serie de factores. En este contexto, la presente investigación da una visión de las restricciones al diseño e implementación de proyectos de mecanismo de desarrollo limpio forestales en la Argentina. Con este fin, se recaba información a partir de la investigación bibliográfica, la entrevista y la aplicación de encuestas para realizar el análisis pertinente bajo la perspectiva de la nueva economía institucional. Consecuentemente, se establece que el escaso crecimiento del sector forestal se debe a la convergencia de diversas restricciones institucionales, organizacionales y tecnológicas. Estas barreras incluyen: la demanda restringida de créditos forestales por parte del esquema de comercio de emisiones de la Unión Europea, elevada incertidumbre institucional relacionada con la continuidad del Protocolo de Kyoto, altos costos de transacción, dificultades técnicas con la aplicación de las metodologías y problemas de financiamiento
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