Mini-uav remote control: a case study at Politecnico di Torino

Recent development of modern micro and nano technologies allows aerospace vehicles extremely small size to be constructed. Wide availability and mass production of small dimension components drastically reduce the price of such vehicles. This fact allows them to be constructed by Universities and it makes them useful for education. The Aerospace Systems Engineering Research Group (ASSET) at Politecnico di Torino the design, development and testing small, but quite complex, integrated systems. The goal of this paper is to present one of the contemporary works of this group: the Mini-UAV "ASSET" remote control/flight simulator site. This paper contains a short presentation of the Mini-UAV, a description of its onboard and ground systems and the use of COTS components. The paper explains how the ground control site has also been designed to run as a flight simulator. For this purpose MICROSOFT FLIGHT SIMULATOR for 3D scenario visualization and Matlab/Simulink for airplane and environmental modeling has been used and integrated. In the system are included possibilities of ALTIA Design software exploitation for avionic display visualization. In particular some new modes for HUD, conceived and simulated, are presented and discussed in the paper. The hardware configuration of the Remote Control System/Flight Simulator is briefly described

Inter-observer variability of clinical target volume delineation in radiotherapy treatment of pancreatic cancer: A multi-institutional contouring experience

Background: An observational multi-institutional study has been conducted aimed to evaluate the inter-observer variability in clinical target volume (CTV) delineation among different radiation oncologists in radiotherapy treatment of pancreatic cancer.Methods: A multi-institutional contouring dummy-run of two different cases of pancreatic cancer treated by postoperative and preoperative radiotherapy (RT) was performed. Clinical history, diagnostics, and planning CT imaging were available on AIRO website (http://www.radioterapiaitalia.it). Participants were requested to delineate CTVs according to their skills and knowledge. Aiming to quantify interobserver variability of CTVs delineations, the total volume, craniocaudal, laterolateral, and anteroposterior diameters were calculated. Descriptive statistic was calculated. The 95% Confidence Interval (95% CI) for coefficient of variation (CV) was estimated. The Dice Similarity Index (DSI) was used to evaluate the spatial overlap accuracy of the different CTVs compared with the CTVs of a national reference Centre considered as a benchmark. The mean DSI (mDSI) was calculated and reported.Results: A total of 18 radiation oncologists from different Institutes submitted the targets. Less variability was observed for the Elective CTV rather than the Boost CTV, in both cases. The estimated CV were 28.8% (95% CI: 21.2 - 45.0%) and 20.0% (95% CI: 14.9 - 30.6%) for the Elective CTV, in adjuvant (Case 1) and neoadjuvant (Case 2) case, respectively. The mDSI value was 0.68 for the Elective CTVs in both cases (range 0.19 - 0.79 in postoperative vs range 0.35 - 0.79 in preoperative case). The mDSI was increased to 0.71 (Case 1) and 0.72 (Case 2) if the observers with a worse agreement have been excluded. On the other hand, a CV of 42.4% (95% CI: 30.1 - 72.4%) and 63.8% (95% CI: 43.9 - 119.2%) with a mDSI value of 0.44 and 0.52, were calculated for the Boost CTV in Case 1 and Case 2, respectively.Conclusions: The CV and mDSI obtained values for Elective CTVs showed an acceptable agreement among participants either in postoperative as well in preoperative setting. Additional strategies to reduce the variability in Boost CTV delineation need to be found and promoted

No benefit of adjuvant Fluorouracil Leucovorin chemotherapy after neoadjuvant chemoradiotherapy in locally advanced cancer of the rectum (LARC): Long term results of a randomized trial (I-CNR-RT)

To evaluate the effect of adjuvant chemotherapy (ACT) in locally advanced rectal cancer (LARC) after neoadjuvant chemoradiation (NACT-RT). The study was funded by the Italian National Research Council (CNR)