Cost effect of uniquely designed component choices of over the product life of a workstation

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997, and Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management, 1997.Includes bibliographical references (p. 83).by Anne Paige Di Censo.M.B.A.M.S

Management of spastic equinovarus foot in children with cerebral palsy: an evaluation of anatomical landmarks for selective nerve blocks of the tibial nerve motor branches

Objective: To define the anatomical landmarks of tibial motor nerve branches for selective motor nerve blocks of the gastrocnemii,  soleus and tibialis posterior muscles in the management of spastic equinovarus foot. Design: Observational study. Patients: Twenty-four children with cerebral palsy with spastic equinovarus foot. Methods: Considering the affected leg length, motor nerve branches to the gastrocnemii, soleus and tibialis posterior muscles were tracked using ultrasonography, and located in the space (vertical, horizontal, deep) according to the position of fibular head (proximal/distal) and a virtual line from the middle of popliteal fossa to the Achilles tendon insertion (medial/lateral). Results: Location of motor branches was defined as percentage of the affected leg length. Mean coordinates were: for the gastrocnemius medialis 2.5 ± 1.2% vertical (proximal), 1.0 ± 0.7% horizontal (medial), 1.5 ± 0.4% deep; for the gastrocnemius lateralis 2.3 ± 1.4% vertical (proximal), 1.1 ± 0.9% horizontal (lateral), 1.6 ± 0.4% deep; for the soleus 2.1 ± 0.9% vertical (distal), 0.9 ± 0.7% horizontal (lateral), 2.2 ± 0.6% deep; for the tibialis posterior 2.6 ± 1.2% vertical (distal), 1.3 ± 1.1% horizontal (lateral), 3.0 ± 0.7% deep. Conclusion: These findings may help the identification of tibial motor nerve branches to perform selective nerve blocks in patients with cerebral palsy with spastic equinovarus foot

Transcriptional, epigenetic and pharmacological control of JAK/STAT pathway in NK cells

Differentiation of Natural Killer (NK) cells is a stepwise process having its origin in the bone marrow and proceeding in the periphery, where these cells follow organ specific trajectories. Several soluble factors and cytokines regulate the distinct stages of NK cell differentiation, and ultimately, their functional properties. Cytokines activating the Janus kinases (JAKs) and members of the signal transducer and activator of transcription (STAT) pathway control distinct aspects of NK cell biology, ranging from development, terminal differentiation, activation, and generation of cells with adaptive properties. Here, we discuss how the recent advances of next generation sequencing (NGS) technology have led to unravel novel molecular aspects of gene regulation, with the aim to provide genomic views of how STATs regulate transcriptional and epigenetic features of NK cells during the different functional stages

Is the outcome of diagnostic nerve block related to spastic muscle echo intensity? A retrospective observational study on patients with spastic equinovarus foot

Objective: To investigate the relationship between spastic calf muscles echo intensity and outcome of tibial nerve motor branches selective block in patients with spastic equinovarus foot. Design: Retrospective observational study. Patients: Forty-eight patients with spastic equinovarus foot. Methods: Each patient was given selective, diagnostic nerve block (lidocaine 2% perineural injection) of the tibial nerve motor branches. All patients were evaluated before and after block. Outcomes: spastic calf muscles echo intensity measured with the Heckmatt scale; affected ankle dorsiflexion passive range of motion; calf muscles spasticity measured with the modified Ashworth scale and the Tardieu scale (grade and angle). Results:  As to the outcome of tibial nerve selective diagnostic block (difference between pre- and post-block condition), the Spearman correlation showed a significant inverse association of the spastic calf muscles echo intensity with the affected ankle dorsiflexion passive range of motion (P=0.045

Memoria de los trabajos realizados por la Junta Provincial del Censo de Población de Valladolid leída en sesión de 25 de Junio de 1839

Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-201

Sexual and reproductive knowledge, attitudes and behaviours in a school going population of Sri Lankan adolescents

The reproductive and sexual health of adolescents is an important health concern and a focus of global attention. In Sri Lanka, a lack of understanding about adolescent reproductive and sexual health needs is a matter of national concern. A survey was undertaken to examine the sexual knowledge, attitudes and behaviours of school going adolescents in Sri Lanka. A random sample of schools was selected from one district. Data were collected by a self-completion questionnaire and analysed using SPSS. Response rate was 90%. 2020 pupils (26% boys, 74% girls) aged 16-19 years (mean = 16.9) participated, the majority Singhalese (97%). Most reported a good parent-child relationship (88%). A minority (34%) discussed sexual issues with parents. Health professionals were the preferred source of sexual information (32%) rather than parents (12.5%) or friends (5.6%). Less than 1% demonstrated satisfactory sexual and reproductive knowledge levels. 1.7% were sexually active (30 boys vs 5 girls), the majority with same age partners. 57% used contraception at first intercourse. There is an imperative to address the lack of sexual and reproductive knowledge. A minority of school going adolescents become sexually active. These individuals are potentially vulnerable and services need to be developed to meet their needs

Larval performance and adult attraction of Delia platura (Diptera: Anthomyiidae) in a native and an introduced crop

Delia platura Meigen is an important pest in crops around the world. Its host range includes almost 50 species and it can develop in soil organic matter. In Ecuador, D. platura is a serious problem for the crop, Lupinus mutabilis Sweet (Chocho) and it also attacks broccoli (Brassica oleracea). After broccoli is harvested, crop residue is mixed with soil or collected and stored close to Chocho fields. The objectives of this study were to determine the adaptive responses of larvae reared on different hosts and whether D. platura females are preferentially attracted to germinating L. mutabilis seeds or broccoli residue. Accordingly, larval performance and attraction of female D. platura reared on broccoli residue and L. mutabilis seeds were evaluated. The number of larvae, pupae and adults were higher when reared on broccoli. Conversely, pupal weight was higher and time from larva to pupa, pupa to adult and total life cycle were longer in flies reared on L. mutabilis. Although D. platura developed more quickly on broccoli, L. mutabilis was also a good host since pupae were heavier compared with flies reared on broccoli. Delia platura females reared on broccoli preferred broccoli residue to L. mutabilis in an olfactometer. Volatiles from broccoli residue in soil may attract D. platura females and stimulate oviposition on L. mutabilis seeds. Environmentally benign production of L. mutabilis crops with minimal insecticide applications may require the elimination of fresh broccoli residue as fertilizer in soils where L. mutabilis is cultivated

High prevalence of malnutrition and nutrition impact symptoms in older patients with cancer:Results of a Brazilian multicenter study

Background Malnutrition in cancer is an independent factor associated with negative clinical outcomes. The objective of this study was to evaluate the prevalence of malnutrition across different age groups in patients with cancer in Brazil and to identify associations with nutrition impact symptoms (NIS). Methods In this observational, cross-sectional, multicenter study, the authors evaluated 4783 patients with cancer aged >= 20 years who were admitted to 45 public hospitals in Brazil. Nutritional status, nutritional risk, and NIS were evaluated using the Patient-Generated Subjective Global Assessment. Results More than one-fourth (25.5%) of all participants were aged >= 65 years. In patients aged >= 65 years, the prevalence of moderate/suspected and severe malnutrition was 55%, it was 45.4% in those aged 51 to 64 years, and it was 36.1% in those aged = 65 years were no appetite (odds ratio [OR], 1.90; 95% CI, 1.62-2.22; P 50 years than in those age

Memoria de la segunda parte de los trabajos : [del] censo de población de 31 de diciembre de 1877 [en la] provincia de León

Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2010-2011Port. a cinco tintas (rojo, morado, negro, verde y ocre