6 research outputs found
GENETICALLY INTERESTING FAMILY WITH NEPHROTIC SYNDROME IN THREE SIBLINGS
WOS: 00044399840035
Predictors of poor kidney outcome in children with C3 glomerulopathy
Background C3 glomerulopathy (C3G) is characterized by heterogeneous clinical presentation, outcome, and predominant C3 accumulation in glomeruli without significant IgG. There is scarce outcome data regarding childhood C3G. We describe clinical and pathological features, treatment and outcomes, and risk factors for progression to chronic kidney disease stage 5 (CKD5) in the largest pediatric series with biopsy-proven C3G