Avances en el desarrollo de un fotobiorreactor para cultivo de microalgas productoras de Astaxantina: Compuestos con alto valor agregado en la industria cosmética y nutracéutica

El diseño e incorporación de tecnologías como un fotobiorreactor de microalgas, la investigación y desarrollo para la optimización de su cultivo y la transferencia de todo el conocimiento generado al sector privado del rubro acuícola, conforman el ensamble necesario para que la ciencia y la industria interactúen de forma próspera hacia una producción optimizada y sustentable, generando un punto de partida para el sector acuícola de la provincia del Chubut, en la Patagonia Argentina.Fil: Martelli, Antonela. Universidad Nacional de la Patagonia "San Juan Bosco"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Vera Piombo, Mercedes. Universidad Nacional de la Patagonia "San Juan Bosco"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Avaro, Marisa Gladis. Universidad Nacional de la Patagonia "San Juan Bosco"; ArgentinaFil: Garralda, Ximena. Universidad Tecnológica Nacional. Facultad Regional Chubut; ArgentinaFil: Castaños, Cecilia. Universidad Tecnológica Nacional. Facultad Regional Chubut; ArgentinaFil: Sepúlveda, Lucas Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; Argentina. Universidad Nacional de la Patagonia "San Juan Bosco"; ArgentinaFil: Rubilar Panasiuk, Cynthia Tamara. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; Argentina. Universidad Nacional de la Patagonia "San Juan Bosco"; ArgentinaX Foro Iberoamericano de los Recursos Marinos y Acuicultura: Sinergia entre ciencia e industria para el desarrollo y la sostenibilidadEspañaForo Iberoamericano de los Recursos Marinos y la Acuicultur

Reproductive biology of the nonnative oyster, Crassostrea gigas (Thunber, 1793) as a key for its successful spread along the rocky shores of Northern Patagonia, Argentina

Crassostrea gigas was introduced in Anegada Bay (North Patagonia, Argentina), in 1981 for aquaculture purposes. The species has, since established in the field, covered all available hard substrata in the bay and gradually expanded south along the coast of the neighboring province of Río Negro, 90 km away from its original introduction site. Our work focused on the reproductive dynamics of the species at the introduction site, with emphasis on the thermal thresholds needed for each stage of gonad development. During early spring, the oysters in Anegada Bay go through active gonad proliferation. Maturity extends mainly from October to January. The first spawning occurs in November, when seawater temperature exceeds 17°C, and peaks from December to February, when seawater temperature lies in the range ot 19–21.5°C. The timing of gonad development is size dependent. Larger (≥70 mm) and medium-size oysters begin spawning first, whereas small oysters ( 17°C), and spawning only occurs in those sites where this threshold is reached.Versión del editor

Zebrafish intestinal colonization by three lactic acid bacteria isolated from Patagonian fish provides evidence for their possible application as candidate probiotic in aquaculture

Studies about probiotics isolated from Patagonian fish are scarce. Three autochthonous lactic acid bacteria (LAB) were previously isolated from Patagonian fish: Carnobacterium sp. T4, Lactococcus lactis TW34, and Lactobacillus pentosus H16. Zebrafish has been extensively used as an experimental vertebrate model; however, this model has recently been used to assess the intestinal bacterial colonization. In this study, we researched the in vitro probiotic properties of the Patagonian LABs T4, TW34, and H16, and their in vivo capability to colonize the gastrointestinal tract of zebrafish. Such strains were tolerant to trout bile and acid pH values, which is an essential property for their survival in the fish gut. H16 was the most resistant strain to low pH values. It specifically adhered to mucus, unlike T4 and TW34 that showed nonspecific adhesion. Zebrafish were fed daily with commercial food supplemented with T4, TW34, or H16 at a final concentration of 107 CFU g−1 of dry food, while the control group was fed only with commercial food. The presence of T4, TW34, and H16 was detected in the zebrafish intestines of the treated groups. After the treatments, changes in the zebrafish intestinal microbiota were recorded. The counts of vibrios and enterobacteria decreased, while the LAB count increased. This study showed that autochthonous LAB strains isolated from Patagonian fish were able to colonize the intestine of the zebrafish and modify the gut microbiota balance towards health-promoting bacteria. These findings propose them as interesting probiotic candidates for use in aquaculture purposes.Fil: Sequeiros, Cynthia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Garcés, Marisa Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico para el Estudio de los Ecosistemas Continentales; ArgentinaFil: Fernández, Melania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Marcos, Magalí Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico para el Estudio de los Ecosistemas Continentales; ArgentinaFil: Castaños, Cecilia. Universidad Tecnológica Nacional. Facultad Regional Chubut; ArgentinaFil: Moris, Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico para el Estudio de los Ecosistemas Continentales; Argentin

Morphology and taxonomy of marine planktonic diatoms of the genus Asteromphalus (Bacillariophyceae) in Antarctic waters and the Southwestern Atlantic Ocean

Diatoms of the genus Asteromphalus are common planktonic species in marine waters all over the world, widespread in warm, temperate and cold water regions. The most conspicuous morphological feature is the presence of distinctive hyaline rays on the valve surface, one of them narrower than the others, alternating with areolate sectors. Some morphological characters traditionally used for differentiating species have limited or no taxonomic value when used in isolation, due to a high degree of variation (e.g. number of rays, proportion of the central portion). However, when ambiguous morphological characteristics are considered together they may be diagnostic, e.g. the shape and width of the rays, position of central portion, shape of separating line and the areolae pattern (type of cribrum). Though previous investigations on this genus have thoroughly described the frustule, only a few have studied inter-specific morphological variations. In order to study the morphology and distribution of Asteromphalus species, a large number of water samples collected during different cruises carried out between 1986 and 2009 in the Southwestern Atlantic and Southern Oceans were examined with light and electron microscopes. Eight species of Asteromphalus have been found in the area, A. arachne, A. emergens, A. flabellatus, A. heptactis, A. hookeri, A. hyalinus, A. parvulus and A. sarcophagus. All the documented species were described and illustrated, and have been supplemented with environmental data (temperature and salinity) and a review from the literature. Additional considerations on their regional occurrence and a morphological comparison with other Asteromphalus species are provided.Fil: Ferrario, Martha Elba. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Cefarelli, Adrián Oscar. Universidad Nacional de la Patagonia Austral. Centro de Investigaciones y Transferencia Golfo San Jorge. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia Golfo San Jorge. Universidad Nacional de la Patagonia "San Juan Bosco". Centro de Investigaciones y Transferencia Golfo San Jorge; Argentina. Universidad Nacional de la Patagonia "San Juan Bosco". Instituto de Desarrollo Costero; ArgentinaFil: Fernandes, Luciano F.. Universidade Federal Do Paraná; BrasilFil: Castaños, Cecilia. Universidad Tecnológica Nacional. Facultad Regional Chubut; ArgentinaFil: Hernández Becerril, David U.. Universidad Nacional Autónoma de México; Méxic

Environmental and societal factors associated with COVID-19-related death in people with rheumatic disease: an observational study

Published by Elsevier Ltd.Background: Differences in the distribution of individual-level clinical risk factors across regions do not fully explain the observed global disparities in COVID-19 outcomes. We aimed to investigate the associations between environmental and societal factors and country-level variations in mortality attributed to COVID-19 among people with rheumatic disease globally. Methods: In this observational study, we derived individual-level data on adults (aged 18-99 years) with rheumatic disease and a confirmed status of their highest COVID-19 severity level from the COVID-19 Global Rheumatology Alliance (GRA) registry, collected between March 12, 2020, and Aug 27, 2021. Environmental and societal factors were obtained from publicly available sources. The primary endpoint was mortality attributed to COVID-19. We used a multivariable logistic regression to evaluate independent associations between environmental and societal factors and death, after controlling for individual-level risk factors. We used a series of nested mixed-effects models to establish whether environmental and societal factors sufficiently explained country-level variations in death. Findings: 14 044 patients from 23 countries were included in the analyses. 10 178 (72·5%) individuals were female and 3866 (27·5%) were male, with a mean age of 54·4 years (SD 15·6). Air pollution (odds ratio 1·10 per 10 μg/m3 [95% CI 1·01-1·17]; p=0·0105), proportion of the population aged 65 years or older (1·19 per 1% increase [1·10-1·30]; p<0·0001), and population mobility (1·03 per 1% increase in number of visits to grocery and pharmacy stores [1·02-1·05]; p<0·0001 and 1·02 per 1% increase in number of visits to workplaces [1·00-1·03]; p=0·032) were independently associated with higher odds of mortality. Number of hospital beds (0·94 per 1-unit increase per 1000 people [0·88-1·00]; p=0·046), human development index (0·65 per 0·1-unit increase [0·44-0·96]; p=0·032), government response stringency (0·83 per 10-unit increase in containment index [0·74-0·93]; p=0·0018), as well as follow-up time (0·78 per month [0·69-0·88]; p<0·0001) were independently associated with lower odds of mortality. These factors sufficiently explained country-level variations in death attributable to COVID-19 (intraclass correlation coefficient 1·2% [0·1-9·5]; p=0·14). Interpretation: Our findings highlight the importance of environmental and societal factors as potential explanations of the observed regional disparities in COVID-19 outcomes among people with rheumatic disease and lay foundation for a new research agenda to address these disparities.MAG is supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant numbers K01 AR070585 and K24 AR074534 [JY]). KDW is supported by the Department of Veterans Affairs and the Rheumatology Research Foundation Scientist Development award. JAS is supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (grant numbers K23 AR069688, R03 AR075886, L30 AR066953, P30 AR070253, and P30 AR072577), the Rheumatology Research Foundation (K Supplement Award and R Bridge Award), the Brigham Research Institute, and the R. Bruce and Joan M. Mickey Research Scholar Fund. NJP is supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (T32-AR-007258). AD-G is supported by grants from the Centers for Disease Control and Prevention and the Rheumatology Research Foundation. RH was supported by the Justus-Liebig University Giessen Clinician Scientist Program in Biomedical Research to work on this registry. JY is supported by grants from the National Institutes of Health (K24 AR074534 and P30 AR070155).info:eu-repo/semantics/publishedVersio