Tropical Isabella grape juices: bioactive compounds and antioxidant power depends on harvest season.

Grapes are important sources of antioxidants compounds and one of the most used varieties to elaborate juices is 'Isabel', or 'Isabella', as it is called in North-America. This study aimed to evaluate the antioxidant activity of Isabella grape juices from the tropical semi-arid climate produced in Brazil on March and September, 2010. Total phenolics and anthocyanins were determined, as well as the antioxidant capacity by DPPH, FRAP and hydrophilic ORAC methods. Test T was used to compare statistical difference at 5% of significance level. As expected, the results showed that the season can play a significant role on phenolics content and antioxidant power. Polyphenols content in juices varied from 82.9 ± 0.92 to 102.2 ± 1.59 mg GAE 100 mL-1 and anthocyanins content ranged from 44.3 ± 2.01 to 129.5 ± 2.82 mg cyanidin-3-glucoside 100 mL-1. Regression analyses showed a high correlation of antioxidant capacity and anthocyanins content. Grapes from Sao Francisco River Valley demonstrated to be a good source of antioxidant for human diet

Extraction of bioactive compounds from Peruvian purple corn cob by high isostatic pressure

The purple corn cob is an agro-industrial by-product that contains high-value bioactive compounds, which makes its use attractive for the development of extraction processes. The aim of this research was to extract the bioactive compounds from the purple corn cob by high isostatic pressure at different processing temperatures. Pressures of 0.01 MPa, 250 MPa, 450 MPa and 650 MPa for 3 minutes and at temperatures of 25 °C, 45 °C and 65 °C were used. High pressure extraction was compared with conventional extraction (2.5 h at 25°C). The purple corn cob extract obtained by isostatic processing at 650 MPa and 65 °C presented high antioxidant activity and content of bioactive compounds, unlike the conventional extraction of 2.5 h and 65 °C (p 0.05). Seven different anthocyanins were identified by liquid chromatography in the extracts obtained by high isostatic pressure (650 MPa at 65 °C) and hydroalcoholic maceration (2.5 h at 65 °C), mainly cyanidin-3-glucoside, pelargonidin-3-glucoside and peonidin-3-glucoside, and their respective malonyl derivatives. The high isostatic pressure increased the extraction of bioactive compounds by more than 50% and obtained them in shorter times, thus appearing as a new alternative, and eco-friendly method for the extraction of bioactive compounds from plant tissues

Tuberculosis care: an evaluability study

OBJECTIVE: to verify whether the tuberculosis control program (TCP) is evaluable and to examine the feasibility of building an evaluation model in apriority municipality for the control of tuberculosis.METHOD: this evaluability study was conducted in a municipality in northeastern Brazil. For data collection, documental analysis and interviews with key informants were performed. For indicator validation, the nominal group technique was adopted.RESULTS: the details of TCP were described, and both the logical model and the classification framework for indicators were developed and agreed up on, with the goal of characterizing the structural elements of the program, defining the structure and process indicators, and formulating the evaluation questions.CONCLUSION: TCP is evaluable. Based on logical operational analysis, it was possible to evaluate the adequacy of the program goals for the control of tuberculosis. Therefore, the performance of a summative evaluation is recommended, with a focus on the analysis of the effects of tuberculosis control interventions on decreasing morbidity and mortality

Sustainability analysis of a health promotion intervention in Recife-PE, Brazil

Iniciativas de promoção de atividade física têm sido apontadas como relevantes na promoção da saúde. O município de Recife, Pernambuco, idealizou e implantou em 2002 política dessa natureza, denominada Programa Academia da Cidade (PAC). A sustentabilidade de intervenções de promoção da saúde constitui um desafio à manutenção dos seus resultados. Objetivou-se analisar o percurso dos eventos relativos à sustentabilidade do PAC Recife no período de 2002 a 2016. Trata-se de pesquisa avaliativo-qualitativa, tendo como estratégia de estudo o caso único. Para a análise dos dados, empregou-se a análise de conteúdo temática. Recolheram-se dados por meio da técnica do incidente crítico, em 14 entrevistas com informantes-chave e seis grupos focais, em dois períodos: de agosto a dezembro de 2010 e de junho a agosto de 2016, e em documentos oficiais e técnicos. Construiu-se a linha do tempo dos eventos/incidentes críticos relativos à sustentabilidade do programa. Os dados foram analisados conforme as seguintes categorias: eventos de implementação, mistos e de sustentabilidade. Os eventos ficaram classificados de acordo com suas consequências em favoráveis ou desfavoráveis à sustentabilidade. Os resultados indicaram ocorrência de 14 eventos/incidentes críticos, na maior parte com consequências positivas para a continuidade do programa no período estudado. Initiatives for promotion of physical activity have been identified as relevant practices in health promotion. The city of Recife-PE, devised and implemented in 2002 a policy called Academia da Cidade Program (ACP). The sustainability of health promotion interventions imposes a challenge to the maintenance of its results. The goal was to analyze the course of events related to the sustainability of the ACP Recife from 2002 to 2016. It is a qualitative evaluative research with a single case study strategy. For data analysis, the thematic content was used. Data was collected using the critical incident technique from 14 interviews with key informants and six focal groups in two periods: from August to December 2010, and June to August 2016; and technical and official documents. A timeline for critical events/incidents related to the program sustainability was created. Data were analyzed according to the following categories: sustainability, mixed and implementation events. Events were classified according to their consequences: favorable or unfavorable to sustainability. The results pointed out to the occurrence of 14 critical events/incidents, most of them with positive consequences to the continuity of the program in the period. Initiatives for promotion of physical activity have been identified as relevant practices in health promotion. The city of Recife-PE, devised and implemented in 2002 a policy called Academia da Cidade Program (ACP). The sustainability of health promotion interventions imposes a challenge to the maintenance of its results. The goal was to analyze the course of events related to the sustainability of the ACP Recife from 2002 to 2016. It is a qualitative evaluative research with a single case study strategy. For data analysis, the thematic content was used. Data was collected using the critical incident technique from 14 interviews with key informants and six focal groups in two periods: from August to December 2010, and June to August 2016; and technical and official documents. A timeline for critical events/incidents related to the program sustainability was created. Data were analyzed according to the following categories: sustainability, mixed and implementation events. Events were classified according to their consequences: favorable or unfavorable to sustainability. The results pointed out to the occurrence of 14 critical events/incidents, most of them with positive consequences to the continuity of the program in the period.publishersversionpublishe