Use of the Choquet Integral for Combination of Classifiers in P300 Based Brain-Computer Interface

One of the key issues in the development of braincomputer interfaces (BCIs) is the improvement of their current information transfer rate. In order to achieve that objective at least two aspects of BCI design should be considered: classification accuracy and protocol specification. In this paper we show how combination of classifiers using fuzzy measures and the Choquet integral can be applied to the context of EEG-based BCI and study whether its use, together with an appropriate application protocol, can lead to an increase in the information transfer rate

Support vector machines to detect physiological patterns for EEG and EMG-based human-computer interaction:a review

Support vector machines (SVMs) are widely used classifiers for detecting physiological patterns in human-computer interaction (HCI). Their success is due to their versatility, robustness and large availability of free dedicated toolboxes. Frequently in the literature, insufficient details about the SVM implementation and/or parameters selection are reported, making it impossible to reproduce study analysis and results. In order to perform an optimized classification and report a proper description of the results, it is necessary to have a comprehensive critical overview of the applications of SVM. The aim of this paper is to provide a review of the usage of SVM in the determination of brain and muscle patterns for HCI, by focusing on electroencephalography (EEG) and electromyography (EMG) techniques. In particular, an overview of the basic principles of SVM theory is outlined, together with a description of several relevant literature implementations. Furthermore, details concerning reviewed papers are listed in tables and statistics of SVM use in the literature are presented. Suitability of SVM for HCI is discussed and critical comparisons with other classifiers are reported

Chikungunya virus (CHIKV) infection: Analytical performance of real-time NASBA assay

n/

Analysis and characterization of mouse monoclonal antibodies reactive to Chikungunya virus (CHIKV)

occurring in 1984). However, plague has made an astonishing comeback in the last decade. Methods: n/a. Results: After a silence of 50 years, an outbreak of bubonic plague suddenly occurred close to Oran in Algeria, in June 2003. Eighteen bubonic cases were identified, and Yersinia pestis was isolated from 6 patients. In July 2008, a new cluster was reported among nomads 300 km south of the first one. Four members of one family were affected and one died. The bacillus was isolated from one patient. No epidemiological association was identified between the two events. On June 2009, 25 years after the last occurrence in the country, Libya reported five confirmed cases of bubonic plague in the Tobruk area. Y. pestis was isolated from three patients. In all these cases, further local ecological investigations confirmed the existence of a natural focus The re-emergence of human plague in the region is not without international consequences. Two of the last concerned natural foci are close to an international port which raises the question of the potential exportation of infected rodents. Cross-border tensions, between ''plague countries'' and ''plague-free countries'' have been observed although the foci's limits are unknown as any systematic ecological investigation and surveillance is lacking. Additionally, the potential weaponization of Y.pestis together with international political tensions feed a recurrent interest in plague in North Africa. False rumors of alleged military laboratory accidents or terrorist acts are routinely mentioned, although events could be first explained by the natural history of the disease. Conclusion: In this context, and although the number of human cases has been very limited so far, the first priorities are to establish appropriate ecological surveillance and agree on a common plague control strategy for the region

Comparative genomic and phylogenetic analysis of the first usutu virus isolate from a human patient presenting with neurological symptoms.

Usutu virus (USUV) is a mosquito-borne flavivirus, belonging to the Japanese encephalitis antigenic complex, that circulates among mosquitoes and birds. We describe and analyze the complete genome sequence of the first USUV strain isolated from an immunocompromised patient with neuroinvasive disease. This USUV isolate showed an overall nucleotide identity of 99% and 96%, respectively, with the genomes of isolates from Europe and Africa. Comparison of the human USUV complete polyprotein sequence with bird-derived strains, showed two unique amino acid substitutions. In particular, one substitution (S595G) was situated in the DIII domain of the viral Envelope protein that is recognized by flavivirus neutralizing antibodies. An additional amino acid substitution (D3425E) was identified in the RNA-dependent RNA polymerase (RdRp) domain of the NS5 protein. This substitution is remarkable since E3425 is highly conserved among the other USUV isolates that were not associated with human infection. However, a similar substitution was observed in Japanese encephalitis and in West Nile viruses isolated from humans. Phylogenetic analysis of the human USUV strain revealed a close relationship with an Italian strain isolated in 2009. Analysis of synonymous nucleotide substitutions (SNSs) among the different USUV genomes showed a specific evolutionary divergence among different countries. In addition, 15 SNSs were identified as unique in the human isolate. We also identified four specific nucleotide substitutions in the 59 and 39 untranslated regions (UTRs) in the human isolate that were not present in the other USUV sequences. Our analyses provide the basis for further experimental studies aimed at defining the effective role of these mutations in the USUV genome, their potential role in the development of viral variants pathogenic for humans and their evolution and dispersal out of Africa

Serological update of the Chikungunya epidemic outbreak in Italy

Serological update of the Chikungunya epidemic outbreak in Italy P. Gaibani1,∗, A. Pierro1, F. CAVRINI2, G. Rossini 3, M.P. Landini 3, C. Manisera4, V. Sambri5 1 S.Orsola-Malpighi, Bologna, Italy 2 S. Orsola-Malpighi Hospital, BOLOGNA, Italy 3 S.Orsola-Malpighi Hospital, section of Microbiology, BOLOGNA, Italy 4 S.Orsola-Malpighi Hospital, Microbiology, Bologna, Italy 5 University of Bologna, Bologna, Ital

Sero-prevalence of West Nile virus in north-eastern Italy

n/

Imported cases of Chikungunya and Dengue fever in Emilia Romagna region, Italy

Imported cases of Chikungunya and Dengue fever in Emilia Romagna region, Italy F. Cavrini 1,∗, P. Gaibani2, C. Manisera3, A. Pierro4, G. Rossini 5, M.P. Landini 5, V. Sambri6 1 S. Orsola-Malpighi Hospital, BOLOGNA, Italy 2 S.Orsola-Malpighi Hospital, Section of Microbiology, BOLOGNA, Italy 3 S.Orsola-Malpighi Hospital, Section of Microbiology, BOLOGNA, Italy 4 S.Orsola-Malpighi, Bologna, Italy 5 S.Orsola-Malpighi Hospital, section of Microbiology, BOLOGNA, Italy 6 University of Bologna, Bologna, Ital

Phylogenetic analysis of West Nile virus isolates, Italy, 2008-2009.

To determine the lineage of West Nile virus that caused outbreaks in Italy in 2008 and 2009, several West Nile virus strains were isolated from human specimens and sequenced. On the basis of phylogenetic analyses, the strains isolated constitute a distinct group within the western Mediterranean cluster

First human case of West Nile virus neuroinvasive infection in Italy, September 2008 - case report.

On 20 September 2008, the laboratory of the Regional Reference Centre for Microbiological Emergencies (Centro di Riferimento Regionale per le Emergenze Microbiologiche, CRREM) in Bologna, reported the detection of specific IgM and IgG antibodies against West Nile virus (WNV) in the serum of a female patient in her eighties who lived in a rural area between Ferrara and Bologna, Italy