The Mutual Emplacement of Europe and Asia on Cartographic Folding Screens in Japan during the Early Modern Period

UID/HIS/04666/2013The panel investigates a selection of seventeenth-century Japanese cartographic folding screens to understand how Japanese cartographers addressed cosmology and world geography by re-elaborating European and East Asian sources through interaction with European merchants and missionariespublishersversionpublishe

Introduction

UID/HIS/04666/2019publishersversionpublishe

Interactions Between Rivals: The Christian Mission and Buddhist Sects in Japan (c.1549-c.1647)

This volume presents comprehensive research on how southern European Catholics and the Japanese confronted each other, interacted and mutually experienced religious otherness in early modern times. In their highly variable and asymmetric relations, during which the politi¬cal-military elites of Japan at times not only favoured, but also opposed and strictly controlled the European presence, missionaries – particularly the Jesuits – tried to negotiate this power balance with their interlocutors. This collection of essays analyses religious and cultural interactions between the Christian missions and the Buddhist sects through processes of coopera¬tion, acceptance, confrontation and rejection, dialogue and imposition, which led to the creation of new relational spaces and identities

Dutch, Spanish and Portuguese maps in the collections of the Grand Duke Cosimo III de’ Medici

UID/HIS/04666/2019«Through the lenses of Dutch, Portuguese and Spanish cartography and landscapes gathered in the cartographic collection of Cosimo III de' Medici, the project The Global Eye reconstructs how connected global world of the mid-17th century was taking shape and reveals a remarkable circulation of men and knowledge between the Netherlands, Portugal and Tuscany during the modern era.»publishersversionpublishe

The Project

UIDB/00417/2020 UIDP/00417/2020 UIDB/04666/2020 UIDP/04666/2020publishersversionpublishe

The Visualization of Knowledge in Medieval and Early Modern Europe

Review of Marcia Kupfer, Adam Cohen, and J. H. Chajes, eds, The Visualization of Knowledge in Medieval and Early Modern Europe (Turnhout: Brepols publisher, 2020

Inventare musei per ordinare e rappresentare il mondo. La Guardaroba nuova di Palazzo Vecchio e le Sale della cosmografia e delle matematiche agli Uffizi a Firenze

Este artigo traça a história da invenção e construção de dois lugares museológicos (um literário e outro real) na Florença da segunda metade do século XVI, chamando a atenção para o seu significado no contexto do saber da época. O projecto cosmográfico para o Guarda-roupa novo do Palazzo Vecchio e as Salas da Cosmografia e das Matemáticas nos Uffizi oferecem a possibilidade de explorar dois sistemas semióticos que permitem explorar os processos de invenção e criação do museu como lugar – literário, imaginário, arquitectónico, epistemológico – no qual e através do qual se ordena e representa o mundo. O primeiro destes espaços é o projecto cosmográfico idealizado por volta de 1560 por Cosimo I, Giorgio Vasari e Miniato Pitti para o Guarda-roupa novo do Palazzo Vecchio, actualmente conhecido, impropriamente, como “Sala das cartas geográficas”. O projecto nunca foi concluído; porém existiu e continua a existir e a fascinar como “espaço literário” através de uma página visionária na segunda edição das Vite de Giorgio Vasari. O segundo lugar é a Sala da Cosmografia, mandada construir por Ferdinando I em 1589, juntamente com a contígua Sala das Matemáticas o da Arquitectura Militar na Galleria degli Uffizi. No centro do novo projecto expositivo, totalmente concluído, pela primeira vez, foram colocados os instrumentos e livros científicos e, implicitamente, o Homem como observador e demiurgo do mundo.Fundação para a Ciência e a Tecnologia (FCT), Fundação Millennium bcp, Ministério da Cultura, Instituto dos Museus e da Conservaçã

Entangled Histories, Catholic Missions and Languages

This essay focuses on the heterogeneous missionary contexts connected to the Portuguese Empire, in the hemisphere assigned to Portugal by the Treaty of Tordesillas (1494) and Zaragoza (1529), ranging from Brasil, Sub-Saharan Africa, to India, Vietnam, China and Japan. In these plural missionary contexts, between ca. 1540 to 1650, Portuguese was used, mostly by the Jesuits and their more numerous local native mediators, as translational language for several idioms unknown in Europe. These early modern linguistic and cultural translations of living languages based on Portuguese as translational language, have largely been overlooked outside of the field of missionary linguistics. This essay highlights instead their strong documentary potential, meaning and implications, beyond linguistics, with respect to current debates on early modern global history and its periodization

Spontaneous Formation of L-Isoaspartate and Gain of Function in Fibronectin

Isoaspartate formation in extracellular matrix proteins, by aspartate isomerization or asparagine deamidation, is generally viewed as a degradation reaction occurring in vivo during tissue aging. For instance, non-enzymatic isoaspartate formation at RGD-integrin binding sites causes loss of cell adhesion sites, which in turn can be enzymatically "repaired" to RGD by protein-L-isoAsp-O- methyltransferase. We show here that isoaspartate formation is also a mechanism for extracellular matrix activation. In particular, we show that deamidation of Asn(263) at the Asn-Gly-Arg (NGR) site in fibronectin N-terminal region generates an alpha(v)beta(3)-integrin binding site containing the L-isoDGR sequence, which is enzymatically "deactivated" to DGR by protein-L-isoAsp-O-methyltransferase. Furthermore, rapid NGR-to-isoDGR sequence transition in fibronectin fragments generates alpha(v)beta(3) antagonists ( named "isonectins") that competitively bind RGD binding sites and inhibit endothelial cell adhesion, proliferation, and tumor growth. Time-dependent generation of isoDGR may represent a sort of molecular clock for activating latent integrin binding sites in proteins

BOOK OF ABSTRACTS

UID/ELT/04097/2013 UID/HIS/04666/2013publishersversionpublishe