15,821 research outputs found

    When Father Doesn't Know Best: Parents’ Management and Control of Money and Children’s Food Insecurity

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    Although developing-country research has found that spending on children's food, healthcare, and education varies depending on which parent controls income, developed-country research on child wellbeing tends to ignore intrahousehold allocation. This study uses data from the Fragile Families and Child Wellbeing Study (N = 820 couples) to analyze how mothers' versus fathers' control of money affects U.S. children's food insecurity. Results show children are least likely to experience food insecurity when parents’ income is pooled and controlled by their mother and most likely to do so when parents’ income is pooled and controlled by their father. Surprisingly, children also fare worse when parents’ pooled income is jointly controlled—the system considered the norm for married-parent households in the United States.

    State Prescription Drug Price Web Sites: How Useful to Consumers?

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    Compares ten sites and identifies key limitations due to data omissions, gaps between insured and uninsured consumers, and varied program implementation. Presents alternative policy options such as requiring price lists from pharmacies

    Comparing demand functions when different price manipulations are used: Does unit price help?

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    Six hens pecked a key (Experiment 1) or pushed a door (Experiment 2) to obtain food reinforcement. In both experiments and as an analogue of price changes, the response requirements were varied in two ways: by increasing the number of responses required and by increasing the required force of each response. The two price manipulations (response number and response force) had different effects on behavior and produced different-shaped demand functions when the rates of consumption were plotted logarithmically against the price analogues. Irrespective of response topography, when the number of required responses was varied, the data paths appeared linear, with slopes close to -1.0. When the required force of each keypeck and doorpush was varied, the data paths were clearly curved, with increasingly steep downward slopes as the force increased. Using the concept of unit price did not fully remove the different effects of the two price manipulations. Those differences are best attributed to the differing times needed in order to complete each response unit under those price manipulations

    Empirical Perspectives on Mediation and Malpractice

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    The use of mediation in the medical malpractice context is examined. The impact of any court-related alternative dispute resolution program is also discussed

    A learning community two years on: reflecting on successes and framing futures

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    This paper reports the results of a participatory action research (PAR) evaluation conducted with the members of the Granite Belt Learners Group in their rural 'learning community' in South East Queensland, and presents an action research and evaluation framework to guide the community on the next stage of its journey

    Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy.

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    Macroautophagy is a fundamental and evolutionarily conserved catabolic process that eradicates damaged and aging macromolecules and organelles in eukaryotic cells. Decorin, an archetypical small leucine-rich proteoglycan, initiates a protracted autophagic program downstream of VEGF receptor 2 (VEGFR2) signaling that requires paternally expressed gene 3 (PEG3). We have discovered that PEG3 is an upstream transcriptional regulator of transcription factor EB (TFEB), a master transcription factor of lysosomal biogenesis, for decorin-evoked endothelial cell autophagy. We found a functional requirement of PEG3 for TFEB transcriptional induction and nuclear translocation in human umbilical vein endothelial and PAER2 cells. Mechanistically, inhibiting VEGFR2 or AMP-activated protein kinase (AMPK), a major decorin-activated energy sensor kinase, prevented decorin-evoked TFEB induction and nuclear localization. In conclusion, our findings indicate a non-canonical (nutrient- and energy-independent) mechanism underlying the pro-autophagic bioactivity of decorin via PEG3 and TFEB
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