Evolution of testosterone treatment over 25 years: symptom responses, endocrine profiles and cardiovascular changes

Introduction: Testosterone treatment has evolved rapidly over the past 25 years as new, more effective and convenient methods have become available. This study reports experience with seven different methods, introduced on the market in the UK. Aim: To establish the symptom response when testosterone treatment was initiated on the basis of clinical features and symptoms of androgen deficiency, and the resulting endocrine, biochemical and physiological responses. Methods: Of 2693 patients attending the 3 Men’s Health Centers – The UK Androgen Study (UKAS), 2247 were treated. Treatments included pellet implants, oral testosterone undecanoate (Testocaps), mesterolone (Proviron), testosterone gel (Testogel), testosterone scrotal cream (Andromen) and scrotal gel (Tostran). Results: There was no correlation between initial testosterone level, initial symptom score or the success of treatment as defined by adequate resolution of symptoms. Despite the diverse endocrine patterns produced, the testosterone preparations appear equally safe over prolonged periods, with either no change or improvement of cardiovascular risk factors, especially in lowering cholesterol and diastolic blood pressure. Conclusions: It is suggested that because of excessive reliance on laboratory measures of androgens and undue safety concerns, many men who could benefit from symptom relief, improvement in related clinical conditions and given preventive medical benefits remain untreated

Internal velocity factors

Computer program analyzes the entries and planetary trajectories of space vehicles. It obtains the equivalence of altitude and flight path angle, respectively, to acceleration load factor with respect to velocity for a given inertial velocity

Concept definition study for recovery of tumbling satellites. Volume 1: Executive summary, study results

The first assessment is made of the design requirements and conceptual definition of a front end kit to be transported on the currently defined Orbital Maneuvering Vehicle (OMV) and the Space Transportation System Shuttle Orbiter, to conduct remote, teleoperated recovery of disabled and noncontrollable, tumbling satellites. Previous studies did not quantify the dynamic characteristics of a tumbling satellite, nor did they appear to address the full spectrum of Tumbling Satellite Recovery systems requirements. Both of these aspects are investigated with useful results

Fragmented Geographies: Tada Fumio and the Japanese Empire in Manchuria, Mengjiang, and Korea

This paper explores the placement and function of the discipline of geography in the expansion of the Japanese empire, doing so through the prism of the work and field research of Tada Fumio, a leading geographer in Japan both before and after 1945. This examination of this aspect of Tada Fumio's career and its interweaving with the construction and consolidation of Japan's empire will broaden recent studies of imperial Japan's simultaneous encounter with geopolitics and fascism while engaging with Japan's developing ideas about geography as a political and cultural discipline. This paper demonstrates the importance of the entwined histories of Japanese and German geographers in the Japanese empire, as well as documenting Tada Fumio's activities in Manchuria (northeast China) and on the Korean peninsula. Finally, the paper reveals fissures in the historical record of Japanese geographers in continental Asia and, until such time as more subaltern voices can be found, seeks to lay down the foundation for further research on the study of geography in the Japanese empire

Concept definition study for recovery of tumbling satellites. Volume 2: Supporting research and technology report

A number of areas of research and laboratory experiments were identified which could lead to development of a cost efficient remote, disable satellite recovery system. Estimates were planned of disabled satellite motion. A concept is defined as a Tumbling Satellite Recovery kit which includes a modular system, composed of a number of subsystem mechanisms that can be readily integrated into varying combinations. This would enable the user to quickly configure a tailored remote, disabled satellite recovery kit to meet a broad spectrum of potential scenarios. The capability was determined of U.S. Earth based satellite tracking facilities to adequately determine the orientation and motion rates of disabled satellites

German Studies of Koreans in Manchuria: Gustav Fochler-Hauke and the Influence of Karl Haushofer’s National Socialist Geopolitics

This article analyses scholarship and memoir writing by German geographer Gustav Fochler-Hauke with respect to Korean settlement in Manchuria, and along the Tumen and Yalu/Amnok rivers in the 1930s and early 40s. The research note demonstrates that while Focher-Hauke’s work has its value—not least due to the access he received thanks to the Japanese military government—his concepts of geopolitics and the influence of his mentor and collaborator, Karl Haushofer, renders the work flawed; its value as a historical source for scholars today is therefore limited. The research note begins with Fochler-Hauke’s rising profile within German geopolitical studies and turns toward that field’s documentation of Koreans in Manchuria, the role of borders between Korea and Manchuria, the blind eye turned toward Korean resistance to Japan, and the rehabilitation of some of these scholars and works after World War II

Home ranges of rusa deer (Cervus timorensis) in a subtropical peri-urban environment in South East Queensland

Wild rusa deer (Cervus timorensis) are increasing in numbers and distribution in peri-urban eastern Australia. To effectively manage rusa deer, land managers need to know the extent of their movements to determine the appropriate scale of control through trapping and shooting. We found that in a subtropical peri-urban environment in South East Queensland, four rusa deer (three male, one female) with GPS collars annually ranged over areas of <400 ha with core areas of ~100 ha over a period of 10–17 months. Our limited data indicated their relatively small home ranges varied little in size and location from season-to-season, suggesting that these deer can be effectively managed at the local level