Nocturnal Diaphoresis Secondary to Mild Obstructive Sleep Apnea in a Patient with a History of Two Malignancies

Numerous medical disorders, including obstructive sleep apnea, may cause nocturnal diaphoresis. Previous work has associated severe obstructive sleep apnea with nocturnal diaphoresis. This case report is of import as our patient with severe nocturnal diaphoresis manifested only mild sleep apnea, and, for years, his nocturnal diaphoresis was ascribed to other causes, i.e., first prostate cancer and then follicular B-cell lymphoma. Additionally, it was the nocturnal diaphoresis and not more common symptoms of obstructive sleep apnea, such as snoring, that led to the definitive diagnosis of his sleep apnea and then to treatment with a gratifying resolution of his onerous symptom

Using the Lane-Change Test (LCT) to Assess Distraction: Tests of Visual-Manual and Speech-Based Operation of Navigation System Interfaces

The Lane Change Test (LCT) is an easy-to-implement, low-cost methodology for the evaluation of the distraction associated with performing invehicle tasks while driving (Mattes, 2003). In the present study, the LCT was used to assess driving performance when drivers completed navigation tasks using visual-manual or speech-based interfaces. Drivers performed two types of navigation tasks at two levels of difficulty. The results provide support for the LCT as an effective measure of distraction for both types of interface. It is recommended that the LCT procedure incorporate additional measures beyond the current mean deviation measure. Two measures are suggested: Lane Change Initiation, which reflects the aspects of driving having to do with detection and response delay as a result of distraction, and a measure of task duration to account for risk exposure

Adolescent Crash Rates and School Start Times in Two Central Virginia Counties, 2009-2011: A Follow-Up Study to a Southeastern Virginia Study, 2007-2008

Background and Objective: Early high school start times (EHSST) may lead to sleep loss in adolescents ( teens ), thus resulting in higher crash rates. (Vorona et al., 2011). In this study, we examined two other adjacent Virginia counties for the two years subsequent to the above-mentioned study. We again hypothesized that teens from jurisdictions with EHSST (versus later) experience higher crash rates. Methods: Virginia Department of Motor Vehicles supplied de-identified aggregate data on weekday crashes and time-of- day for 16-18 year old (teen) and adult drivers for school years 2009-2010 and 2010-2011 in Henrico and Chesterfield Counties (HC and CC, respectively). Teen crash rates for counties with early (CC) versus later (HC) school start-times were compared using two-sample Z-tests and these compared to adult crash rates using pair-wise tests. Results: Chesterfield teens manifested a statistically higher crash rate of 48.8/1,000 licensed drivers versus Henrico\u27s 37.9/1,000 (p = 0.04) for 2009-2010. For 2010-2011, CC 16-17 year old teens demonstrated a statistically significant higher crash rate (53.2/1,000 versus 42.0/1,000), while for 16-18 teens a similar trend was found, albeit nonsignificant (p = 0.09). Crash peaks occurred 1 hour earlier in the morning and 2 hours earlier in the afternoon in Chesterfield, consistent with commute times. Post hoc analyses found significantly more run-off road crashes to the right (potentially sleep-related) in Chesterfield teens. Adult crash rates and traffic congestion did not differ between counties. Conclusions: Higher teen crash rates occurred in jurisdictions with EHSST, as in our prior study. This study contributes to and extends existing data on preventable teen crashes and high school start times

Symptoms of Gastro-Oesophageal Reflux Disease and the Severity of Obstructive Sleep Apnoea Syndrome Are Not Related in Sleep Disorders Center Patients

Background: Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship. Aim: To determine the relationship between OSAS and symptoms of GERD. Methods: Consecutive patients referred to the Sleep Disorders Center (SDC) 18 years and older with polysomnographically defined OSAS were evaluated prospectively for GERD using a validated symptoms questionnaire. The GERD and OSAS relationship was assessed by 1) determining frequency of GERD in patients with and without OSAS; 2) ascertaining the relationship between OSAS severity categories and presence of GERD; 3) examining GERD score in relation to those factors that might affect both GERD and OSAS, e.g. obesity. Results: One thousand and twenty-three SDC patients met entry citeria. Amongst participants, GERD was common (29% of women and 17% of males) and OSAS extremely common (58% of women and 80% of males). GERD score did not correlate with OSAS variables. The severity of OSAS did not influence the prevalence of GERD. Conclusion: In a large group of patients referred to a sleep disorders center, there was no relationship between OSAS and GERD symptoms. Also, there was no relationship between the severity of OSAS and the likelihood of GERD symptoms

Kiri Johannes Ammann'ile

Catesby, Marc, 1679-1749, inglise loodusteadlaneAmmann, Johannes, 1707-1741, šveitsi arst ja botaanik, Peterburi TA liigeErialased teaduslikud küsimuse