5,774 research outputs found
Dynamics of Stripes in Doped Antiferromagnets
We study the dynamics of the striped phase, which has previously been
suggested to be the ground state of a doped antiferromagnet. Starting from the
t-J model, we derive the classical equation governing the motion of the charged
wall by using a ficticious spin model as an intermediate step. A wave-like
equation of motion is obtained and the wall elasticity and mass density
constants are derived in terms of the t and J parameters. The wall is then
regarded as an elastic string which will be trapped by the pinning potential
produced by randomly distributed impurities. We evaluate the pinning potential
and estimate the threshold electric field which has to be applied to the system
in order to release the walls. Besides, the dynamics of the stripe in the
presence of a bias field below the threshold is considered and the high- and
low-temperature relaxation rates are derived.Comment: 22 pages, RevTeX, 3 PS-figure
Combined intervention with pioglitazone and n-3 fatty acids in metformin-treated type 2 diabetic patients: improvement of lipid metabolism
Background: The marine n-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) exert numerous beneficial effects on health, but their potency to improve treatment of type 2 diabetic (T2D) patients remains poorly characterized. We aimed to evaluate the effect of a combination intervention using EPA?+?DHA and the insulin-sensitizing drug pioglitazone in overweight/obese T2D patients already treated with metformin.Methods: In a parallel-group, four-arm, randomized trial, 69 patients (66 % men) were assigned to 24-week-intervention using: (i) corn oil (5 g/day; Placebo), (ii) pioglitazone (15 mg/day; Pio), (iii) EPA?+?DHA concentrate (5 g/day, containing ~2.8 g EPA?+?DHA; Omega-3), or (iv) pioglitazone and EPA?+?DHA concentrate (Pio& Omega-3). Data from 60 patients were used for the final evaluation. At baseline and after intervention, various metabolic markers, adiponectin and cytokines were evaluated in serum using standard procedures, EPA?+?DHA content in serum phospholipids was evaluated using shotgun lipidomics and mass spectrometry, and hyperinsulinemic-euglycemic clamp and meal test were also performed. Indirect calorimetry was conducted after the intervention. Primary endpoints were changes from baseline in insulin sensitivity evaluated using hyperinsulinemic-euglycemic clamp and in serum triacylglycerol concentrations in fasting state. Secondary endpoints included changes in fasting glycemia and glycated hemoglobin (HbA1c), changes in postprandial glucose, free fatty acid and triacylglycerol concentrations, metabolic flexibility assessed by indirect calorimetry, and inflammatory markers.Results: Omega-3 and Pio& Omega-3 increased EPA?+?DHA content in serum phospholipids. Pio and Pio& Omega-3 increased body weight and adiponectin levels. Both fasting glycemia and HbA1c were increased by Omega-3, but were unchanged by Pio& Omega-3. Insulin sensitivity was not affected by Omega-3, while it was improved by Pio& Omega-3. Fasting triacylglycerol concentrations and inflammatory markers were not significantly affected by any of the interventions. Lipid metabolism in the meal test and metabolic flexibility were additively improved by Pio& Omega-3.Conclusion: Besides preventing a modest negative effect of n-3 fatty acids on glycemic control, the combination of pioglitazone and EPA?+?DHA can be used to improve lipid metabolism in T2D patients on stable metformin therapy.Trial registration: EudraCT number 2009-011106-42.<br/
Positivity, entanglement entropy, and minimal surfaces
The path integral representation for the Renyi entanglement entropies of
integer index n implies these information measures define operator correlation
functions in QFT. We analyze whether the limit , corresponding
to the entanglement entropy, can also be represented in terms of a path
integral with insertions on the region's boundary, at first order in .
This conjecture has been used in the literature in several occasions, and
specially in an attempt to prove the Ryu-Takayanagi holographic entanglement
entropy formula. We show it leads to conditional positivity of the entropy
correlation matrices, which is equivalent to an infinite series of polynomial
inequalities for the entropies in QFT or the areas of minimal surfaces
representing the entanglement entropy in the AdS-CFT context. We check these
inequalities in several examples. No counterexample is found in the few known
exact results for the entanglement entropy in QFT. The inequalities are also
remarkable satisfied for several classes of minimal surfaces but we find
counterexamples corresponding to more complicated geometries. We develop some
analytic tools to test the inequalities, and as a byproduct, we show that
positivity for the correlation functions is a local property when supplemented
with analyticity. We also review general aspects of positivity for large N
theories and Wilson loops in AdS-CFT.Comment: 36 pages, 10 figures. Changes in presentation and discussion of
Wilson loops. Conclusions regarding entanglement entropy unchange
Klein tunneling in graphene: optics with massless electrons
This article provides a pedagogical review on Klein tunneling in graphene,
i.e. the peculiar tunneling properties of two-dimensional massless Dirac
electrons. We consider two simple situations in detail: a massless Dirac
electron incident either on a potential step or on a potential barrier and use
elementary quantum wave mechanics to obtain the transmission probability. We
emphasize the connection to related phenomena in optics, such as the
Snell-Descartes law of refraction, total internal reflection, Fabry-P\'erot
resonances, negative refraction index materials (the so called meta-materials),
etc. We also stress that Klein tunneling is not a genuine quantum tunneling
effect as it does not necessarily involve passing through a classically
forbidden region via evanescent waves. A crucial role in Klein tunneling is
played by the conservation of (sublattice) pseudo-spin, which is discussed in
detail. A major consequence is the absence of backscattering at normal
incidence, of which we give a new shorten proof. The current experimental
status is also thoroughly reviewed. The appendix contains the discussion of a
one-dimensional toy model that clearly illustrates the difference in Klein
tunneling between mono- and bi-layer graphene.Comment: short review article, 18 pages, 14 figures; v3: references added,
several figures slightly modifie
Gauge theory in deformed N=(1,1) superspace
We review the non-anticommutative Q-deformations of N=(1,1) supersymmetric
theories in four-dimensional Euclidean harmonic superspace. These deformations
preserve chirality and harmonic Grassmann analyticity. The associated field
theories arise as a low-energy limit of string theory in specific backgrounds
and generalize the Moyal-deformed supersymmetric field theories. A
characteristic feature of the Q-deformed theories is the half-breaking of
supersymmetry in the chiral sector of the Euclidean superspace. Our main focus
is on the chiral singlet Q-deformation, which is distinguished by preserving
the SO(4) Spin(4) ``Lorentz'' symmetry and the SU(2) R-symmetry. We present the
superfield and component structures of the deformed N=(1,0) supersymmetric
gauge theory as well as of hypermultiplets coupled to a gauge superfield:
invariant actions, deformed transformation rules, and so on. We discuss quantum
aspects of these models and prove their renormalizability in the abelian case.
For the charged hypermultiplet in an abelian gauge superfield background we
construct the deformed holomorphic effective action.Comment: 1+60 pages, typos corrected, references adde
Limits of minimal models and continuous orbifolds
The lambda=0 't Hooft limit of the 2d W_N minimal models is shown to be
equivalent to the singlet sector of a free boson theory, thus paralleling
exactly the structure of the free theory in the Klebanov-Polyakov proposal. In
2d, the singlet sector does not describe a consistent theory by itself since
the corresponding partition function is not modular invariant. However, it can
be interpreted as the untwisted sector of a continuous orbifold, and this point
of view suggests that it can be made consistent by adding in the appropriate
twisted sectors. We show that these twisted sectors account for the `light
states' that were not included in the original 't Hooft limit. We also show
that, for the Virasoro minimal models (N=2), the twisted sector of our orbifold
agrees precisely with the limit theory of Runkel & Watts. In particular, this
implies that our construction satisfies crossing symmetry.Comment: 33 pages; v2: minor improvements and references added, published
versio
Exploring Three-dimensional Higher-Spin Supergravity based on sl(N |N - 1) Chern-Simons theories
We investigate various aspects of higher-spin anti-de Sitter supergravity in
three dimensions as described by Chern-Simons theory based on the
finite-dimensional superalgebra sl(N |N - 1), with the particular case of N = 3
as our prime example. This class of theories serves as a natural
supersymmetrization of the higher-spin gravity theory based on sl(N)
Chern-Simons theories. We demonstrate explicitly that the asymptotic symmetry
algebra contains the N = 2 superconformal algebra in each sector. The
appropriate Killing spinor equations are derived and used to classify existing
and new classical solutions. We also discuss holonomy conditions, higher-spin
black holes and conical defect spacetimes in this class of theories.Comment: 41 pages, a few typos in v4 correcte
3D Gasdynamic Modelling of the Changes in the Flow Structure During Transition From Quiescent to Active State in Symbiotic Stars
The results of 3D modelling of the flow structure in the classical symbiotic
system Z~Andromedae are presented. Outbursts in systems of this type occur when
the accretion rate exceeds the upper limit of the steady burning range.
Therefore, in order to realize the transition from a quiescent to an active
state it is necessary to find a mechanism able to sufficiently increase the
accretion rate on a time scale typical to the duration of outburst development.
Our calculations have confirmed the transition mechanism from quiescence to
outburst in classic symbiotic systems suggested earlier on the basis of 2D
calculations (Bisikalo et al, 2002). The analysis of our results have shown
that for wind velocity of 20 km/s an accretion disc forms in the system. The
accretion rate for the solution with the disc is ~22.5-25% of the mass loss
rate of the donor, that is, ~4.5-5*10^(-8)Msun/yr for Z And. This value is in
agreement with the steady burning range for white dwarf masses typically
accepted for this system. When the wind velocity increases from 20 to 30 km/s
the accretion disc is destroyed and the matter of the disc falls onto the
accretor's surface. This process is followed by an approximately twofold
accretion rate jump. The resulting accretion rate growth is sufficient for
passing the upper limit of the steady burning range, thereby bringing the
system into an active state. The time during which the accretion rate is above
the steady burning value is in a very good agreement with observations.
The analysis of the results presented here allows us to conclude that small
variations in the donor's wind velocity can lead to the transition from the
disc accretion to the wind accretion and, as a consequence, to the transition
from quiescent to active state in classic symbiotic stars.Comment: 21 pages, 7 figure
Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs
<p>Abstract</p> <p>Background</p> <p>Host protein-protein interaction networks are altered by invading virus proteins, which create new interactions, and modify or destroy others. The resulting network topology favors excessive amounts of virus production in a stressed host cell network. Short linear peptide motifs common to both virus and host provide the basis for host network modification.</p> <p>Methods</p> <p>We focused our host-pathogen study on the binding and competing interactions of HIV-1 and human proteins. We showed that peptide motifs conserved across 70% of HIV-1 subtype B and C samples occurred in similar positions on HIV-1 proteins, and we documented protein domains that interact with these conserved motifs. We predicted which human proteins may be targeted by HIV-1 by taking pairs of human proteins that may interact via a motif conserved in HIV-1 and the corresponding interacting protein domain.</p> <p>Results</p> <p>Our predictions were enriched with host proteins known to interact with HIV-1 proteins ENV, NEF, and TAT (p-value < 4.26E-21). Cellular pathways statistically enriched for our predictions include the T cell receptor signaling, natural killer cell mediated cytotoxicity, cell cycle, and apoptosis pathways. Gene Ontology molecular function level 5 categories enriched with both predicted and confirmed HIV-1 targeted proteins included categories associated with phosphorylation events and adenyl ribonucleotide binding.</p> <p>Conclusion</p> <p>A list of host proteins highly enriched with those targeted by HIV-1 proteins can be obtained by searching for host protein motifs along virus protein sequences. The resulting set of host proteins predicted to be targeted by virus proteins will become more accurate with better annotations of motifs and domains. Nevertheless, our study validates the role of linear binding motifs shared by virus and host proteins as an important part of the crosstalk between virus and host.</p
Photon and neutral pion production in Au+Au collisions at sqrt(s_{NN}) = 130 GeV
We report the first inclusive photon measurements about mid-rapidity
(|y|<0.5) from Au+Au collisions at sqrt(s_{NN}) = 130 GeV at RHIC. Photon pair
conversions were reconstructed from electron and positron tracks measured with
the Time Projection Chamber (TPC) of the STAR experiment. With this method, an
energy resolution of Delta(E)/E = 2% at 0.5 GeV has been achieved.
Reconstructed photons have also been used to measure the transverse momentum
(pt) spectra of pi0 mesons about mid-rapidity (|y| photon
photon decay channel. The fractional contribution of the pi0 -> photon photon
decay to the inclusive photon spectrum decreases by 20% +/- 5% between pt =
1.65 GeV/c and pt = 2.4 GeV/c in the most central events, indicating that
relative to pi0 -> photon photon decay the contribution of other photon sources
is substantially increasing.Comment: 13 pages, 14 figures, submitted to Phys. Rev.
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