1,499 research outputs found

    Marginally Better: My Husband’s Lover And Gay Portrayal

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    My Husband’s Lover is a Philippine telenovela that has garnered critical and commercial success (and along the way catapulting its two stars to A-list status), mainly due to a premise that heavily mirrors Ang Lee’s Brokeback Mountain (2005) but that which is unique to generally conservative Philippine society. Two high school best friends Eric Del Mundo (Dennis Trillo) and Vincent Soriano (Tom Rodriguez) also happen to be high school sweethearts, with the former leaving the latter.. Likewise, the latter’s family is the typical conservative Filipino family, so he decided to conceal his homosexuality for fear of being disowned. The two reunite years later, with Eric returning from the United States and learning that his former lover is engaged and is expecting a child with Lally Agatep (Carla Abellana). The series details the continuation of Vincent’s and Eric’s (still hidden) romance, and the former’s internal conflict, that between his true feelings and his morals. The dynamics of a love triangle peculiar to the average Filipino audience separate it from the typical Filipino romantic plotline, the portrayal of homosexuality being another Philippine TV trope that has been amply twisted so that it is “fresh.” Instead of the usual flamboyant gay best friend, the homosexuals are not only far from flamboyant, but are also the main characters of the series. Instead of being staples of beauty salons speaking in seeming code that is actually gay lingo, the homosexuals are affluent and well-spoken. The authors will buttress their textual analysis of all ten seasons of My Husband’s Lover with literature on the bakla and the global gay. With queer theory as the framework of the study, with emphasis on the theory’s element of performativity, the authors will also use several significant instances throughout the ten seasons of the series as premises to one of queer theory’s assumptions, that gender is fluid

    Prevalencia del sobrepeso y obesidad en la población infantil nacional y región del Maule

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    69 p.En las últimas cuatro décadas los índices de sobrepeso y obesidad infantil han aumentado sostenidamente, comenzando a presentarse cada vez en edades más tempranas. Por lo que el propósito de esta revisión es dar a conocer la prevalencia de sobrepeso-obesidad infantil entre los años 2015 y 2019, teniendo como objetivo general caracterizar la prevalencia de sobrepeso y obesidad infantil en la Región del Maule. Como conclusión se puede ver que la edad en la que se presenta mayor prevalencia de sobrepeso y obesidad, en la Región del Maule, es entre 5 y 9 años, con cifras alarmantes, viéndose más afectados los niños que las niñas. Estos datos fueron concordantes con la situación que se presenta a nivel nacional, dado que los niños de quinto año básico son los que poseen mayores índices de sobrepeso y obesidad, viéndose una tendencia hacia los hombres más que hacia las mujeres, lo que conlleva a pensar en nuevas estrategias para atacar esta enfermedad

    Efecto de la magnificación en localización de canales accesorios u ocultos durante el acceso endodóntico

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    24 p.Durante el tratamiento endodóntico, conocer la anatomía de los conductos radiculares es fundamental para el éxito, y no abordarlos en su totalidad, puede repercutir en el resultado final de la terapia. El objetivo de esta investigación fue analizar la evidencia sobre la utilidad de los aparatos de magnificación versus la visión macroscópica en la detección de los canales accesorios u ocultos de molares durante el acceso endodóntico. Se realizó una revisión de la literatura en el metabuscador PUB MED, realizando dos búsquedas con distintas combinaciones con términos MESH. Se incluyeron estudios clínicos sobre molares in vitro y aparatos de magnificación versus sin magnificación. Se eliminaron los duplicados y se realizó filtro por título y abstract. Finalmente, se realizó la revisión de los estudios completos obteniendo un total de 14 estudios de los cuales 10 fueron seleccionados para el análisis de resultados. La totalidad de los estudios incluidos en esta revisión concluyen que la magnificación aumenta la cantidad de canales accesorios u ocultos detectados y que el microscopio es el aparato más eficaz ya que otorga la máxima magnificación e iluminación. PALABRAS CLAVE: Root canal, molar, microscopy, lenses, endodontic

    Identificación de genes reguladores involucrados en la respuesta a estrés salinos en dos portainjertos con respuestas contrastantes mediante el análisis de datos de secuenciación masiva

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    55 p.La salinización de los suelos empleados para cultivo resulta ser un factor que influye negativamente en el crecimiento y desarrollo de organismos vegetales con valor comercial. Variadas herramientas se han testeado para plantear una solución válida a este problema, ya que la salinización de suelos tiende a afectar estructuralmente las células vegetales, además de incidir negativamente en el proceso de fotosíntesis. Una de las soluciones agronómicas más efectivas para hacer frente a esta problemática resulta en el desarrollo de organismos vegetales bimembres constituidos por un injerto con características productivas deseables y por un portainjerto (raíces) derivado de plantas tolerantes a concentraciones elevadas de sal en el suelo donde se ubican. El entender qué procesos biológicos subyacen a la tolerancia a estreses abióticos, tales como el estrés salino, es un factor clave para guiar el proceso de mejoramiento genético de portainjertos. Las técnicas de secuenciación masiva se han vuelto una de las metodologías usadas para descifrar estos procesos. En este trabajo se analizaron 48 librerías de secuenciación masiva RNA-seq de dos portainjertos derivados del género Prunus (Prunus avium L. y Prunus cerasifera x munsoniana con respuesta contrastante frente a estrés salino mediante el uso de herramientas bioinformáticas para la determinación de genes reguladores. Se encontraron genes codificadores de factores de transcripción a las seis horas en Prunus cerasifera x munsoniana que no se encuentran en Prunus cerasifera, los cuales interactúan directamente con proteínas membranales. También se encontraron genes codificadores de proteínas clave para la respuesta en primera fase ante estrés salino en Prunus cerasifera x munsoniana que no se encuentran en Prunus avium. // ABSTRACT: The salinization of crop soils is a factor that negatively influences the growth and development of plant organisms with commercial value. Various tools have been tested to propose a valid solution to this problem, since the salinization of soils tends to structurally affect plant cells, in addition to negatively affecting the photosynthesis process. One of the most effective agronomic solutions to face this problem results in the development of two-membered plant organisms made up of a graft with desirable productive characteristics and a rootstock derived from plants that are tolerant to high concentrations of salt in the soil where they are located. Understanding which biological processes underlie tolerance to abiotic stresses, such as salt stress, is a key factor in guiding the rootstock breeding process. Massive sequencing techniques have become one of the methodologies used to decode these processes. In this work, 48 RNA-seq libraries of two rootstocks derived from the genus Prunus (Prunus avium L and Prunus cerasifera x munsoniana) with contrasting response to salt stress were analyzed using bioinformatics tools with the aim of determinate regulatory genes. Genes encoding transcription factors were found at six hours in Prunus cerasifera x munsoniana that are not found in Prunus avium, which interact directly with membrane proteins. Key protein coding genes for the first-phase response to salt stress were also found in Prunus cerasifera x munsoniana that are not found in Prunus avium

    Robust Detection of Hierarchical Communities from Escherichia coli Gene Expression Data

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    Determining the functional structure of biological networks is a central goal of systems biology. One approach is to analyze gene expression data to infer a network of gene interactions on the basis of their correlated responses to environmental and genetic perturbations. The inferred network can then be analyzed to identify functional communities. However, commonly used algorithms can yield unreliable results due to experimental noise, algorithmic stochasticity, and the influence of arbitrarily chosen parameter values. Furthermore, the results obtained typically provide only a simplistic view of the network partitioned into disjoint communities and provide no information of the relationship between communities. Here, we present methods to robustly detect coregulated and functionally enriched gene communities and demonstrate their application and validity for Escherichia coli gene expression data. Applying a recently developed community detection algorithm to the network of interactions identified with the context likelihood of relatedness (CLR) method, we show that a hierarchy of network communities can be identified. These communities significantly enrich for gene ontology (GO) terms, consistent with them representing biologically meaningful groups. Further, analysis of the most significantly enriched communities identified several candidate new regulatory interactions. The robustness of our methods is demonstrated by showing that a core set of functional communities is reliably found when artificial noise, modeling experimental noise, is added to the data. We find that noise mainly acts conservatively, increasing the relatedness required for a network link to be reliably assigned and decreasing the size of the core communities, rather than causing association of genes into new communities.Comment: Due to appear in PLoS Computational Biology. Supplementary Figure S1 was not uploaded but is available by contacting the author. 27 pages, 5 figures, 15 supplementary file

    Control and Characterization of Individual Grains and Grain Boundaries in Graphene Grown by Chemical Vapor Deposition

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    The strong interest in graphene has motivated the scalable production of high quality graphene and graphene devices. Since large-scale graphene films synthesized to date are typically polycrystalline, it is important to characterize and control grain boundaries, generally believed to degrade graphene quality. Here we study single-crystal graphene grains synthesized by ambient CVD on polycrystalline Cu, and show how individual boundaries between coalescing grains affect graphene's electronic properties. The graphene grains show no definite epitaxial relationship with the Cu substrate, and can cross Cu grain boundaries. The edges of these grains are found to be predominantly parallel to zigzag directions. We show that grain boundaries give a significant Raman "D" peak, impede electrical transport, and induce prominent weak localization indicative of intervalley scattering in graphene. Finally, we demonstrate an approach using pre-patterned growth seeds to control graphene nucleation, opening a route towards scalable fabrication of single-crystal graphene devices without grain boundaries.Comment: New version with additional data. Accepted by Nature Material

    How paper folds: bending with local constraints

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    A variational framework is introduced to describe how a surface bends when it is subject to local constraints on its geometry. This framework is applied to describe the patterns of a folded sheet of paper. The unstretchability of paper implies a constraint on the surface metric; bending is penalized by an energy quadratic in mean curvature. The local Lagrange multipliers enforcing the constraint are identified with a conserved tangential stress that couples to the extrinsic curvature of the sheet. The framework is illustrated by examining the deformation of a flat sheet into a generalized cone.Comment: 20 pages, 1 figur

    Accreting Millisecond X-Ray Pulsars

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    Accreting Millisecond X-Ray Pulsars (AMXPs) are astrophysical laboratories without parallel in the study of extreme physics. In this chapter we review the past fifteen years of discoveries in the field. We summarize the observations of the fifteen known AMXPs, with a particular emphasis on the multi-wavelength observations that have been carried out since the discovery of the first AMXP in 1998. We review accretion torque theory, the pulse formation process, and how AMXP observations have changed our view on the interaction of plasma and magnetic fields in strong gravity. We also explain how the AMXPs have deepened our understanding of the thermonuclear burst process, in particular the phenomenon of burst oscillations. We conclude with a discussion of the open problems that remain to be addressed in the future.Comment: Review to appear in "Timing neutron stars: pulsations, oscillations and explosions", T. Belloni, M. Mendez, C.M. Zhang Eds., ASSL, Springer; [revision with literature updated, several typos removed, 1 new AMXP added
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