3,687 research outputs found

    Full-scale crash test of a CH-47C helicopter

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    A full-scale crash test of a large troop/cargo carrying CH-47C helicopter was conducted at the Langley impact dynamics research facility. The crash test of this large helicopter was performed as part of a joint U.S. Army-NASA helicopter test program to provide dynamic structural and seat response data. The test, the procedures employed, the instrumentation, a general assessment of the resulting damage, and typical levels of accelerations experienced during the crash are reported. Various energy-absorbing seating systems for crew and troops were installed and instrumented to provide data for use in the development of design criteria for future aircraft. The crash conditions were selected to simulate known crash conditions and are representative of the 95th percentile accident environment for an autorotating helicopter. Visual examination of the crashed test specimen indicated irreparable damage to many of the structural components. The highest accelerations were recorded by the accelerometers located on the cabin floor in the aft section of the helicopter, directly above the primary impact location and on the floor of the cockpit above the secondary impact location(s)

    Light airplane crash tests at three roll angles

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    Three similar twin engine general aviation airplanes were crash tested at the Langley impact dynamics research facility at 27 m/sec and at nominal roll angles of 0 deg, -15 deg, and -30 deg. Other flight parameters were held constant. The test facility, instrumentation, test specimens, and test method are briefly described. Structural damage and accelerometer data for each of the three impact conditions are presented and discussed

    Light airplane crash tests at three flight-path angles

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    Three similar twin engine general aviation airplane specimens were crash tested at Langley impact dynamics research facility at 27 m/sec and at flight-path angles of -15 deg, -30 deg, and -45 deg. Other flight parameters were held constant. The test facility, instrumentation, test specimens, and test method are briefly described. Structural damage and accelerometer data for each of the three impact conditions are presented and discussed

    Crash tests of three identical low-wing single-engine airplane

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    Three identical four place, low wing single engine airplane specimens with nominal masses of 1043 kg were crash tested under controlled free flight conditions. The tests were conducted at the same nominal velocity of 25 m/sec along the flight path. Two airplanes were crashed on a concrete surface (at 10 and 30 deg pitch angles), and one was crashed on soil (at a -30 deg pitch angle). The three tests revealed that the specimen in the -30 deg test on soil sustained massive structural damage in the engine compartment and fire wall. Also, the highest longitudinal cabin floor accelerations occurred in this test. Severe damage, but of lesser magnitude, occurred in the -30 deg test on concrete. The highest normal cabin floor accelerations occurred in this test. The least structural damage and lowest accelerations occurred in the 10 deg test on concrete

    Meeting in the middle: Fred L. Casmir\u27s contributions to the field of intercultural communication

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    Fred Casmir\u27s third culture building (TCB) framework made a major theoretical contribution to communication studies. Casmir conceptualized the framework as an active process whereby different cultural groups come together to form a third culture between them. The third culture then becomes a common ground for all participants; a cognitive space that incorporates elements of both cultures and yet remains separate and distinct. Third culture building is a departure from adoption (the process of taking on the cultural mores of another) or adaptation (modifying one\u27s cultural mores to better fit those of another), and achieved through deliberate development in an extended process, during which all participants gain an understanding of, and appreciation for, one another. In this essay, the authors review the life and work of Fred Casmir – a leading figure in establishing intercultural communication as a specific area of study. Next the authors discuss the ideological foundations, intended use, key applications and heuristic value of Casmir\u27s third culture building framework

    Modeling the power flow in normal conductor-insulator-superconductor junctions

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    Normal conductor-insulator-superconductor (NIS) junctions promise to be interesting for x-ray and phonon sensing applications, in particular due to the expected self-cooling of the N electrode by the tunneling current. Such cooling would enable the operation of the active element of the sensor below the cryostat temperature and at a correspondingly higher sensitivity. It would also allow the use of MS junctions as microcoolers. At present, this cooling has not been realized in large area junctions (suitable for a number of detector applications). In this article, we discuss a detailed modeling of the heat flow in such junctions; we show how the heat flow into the normal electrode by quasiparticle back-tunneling and phonon absorption from quasiparticle pair recombination can overcompensate the cooling power. This provides a microscopic explanation of the self-heating effects we observe in our large area NIS junctions. The model suggests a number of possible solutions

    Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways

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    BACKGROUND: Interpretation of lists of genes or proteins with altered expression is a critical and time-consuming part of microarray and proteomics research, but relatively little attention has been paid to methods for extracting biological meaning from these output lists. One powerful approach is to examine the expression of predefined biological pathways and gene sets, such as metabolic and signaling pathways and macromolecular complexes. Although many methods for measuring pathway expression have been proposed, a systematic analysis of the performance of multiple methods over multiple independent data sets has not previously been reported. RESULTS: Five different measures of pathway expression were compared in an analysis of nine publicly available mRNA expression data sets. The relative sensitivity of the metrics varied greatly across data sets, and the biological pathways identified for each data set are also dependent on the choice of pathway activation metric. In addition, we show that removing incoherent pathways prior to analysis improves specificity. Finally, we create and analyze a public map of pathway expression in human tissues by gene-set analysis of a large compendium of human expression data. CONCLUSION: We show that both the detection sensitivity and identity of pathways significantly perturbed in a microarray experiment are highly dependent on the analysis methods used and how incoherent pathways are treated. Analysts should thus consider using multiple approaches to test the robustness of their biological interpretations. We also provide a comprehensive picture of the tissue distribution of human gene pathways and a useful public archive of human pathway expression data

    What lies beneath? The role of informal and hidden networks in the management of crises

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    Crisis management research traditionally focuses on the role of formal communication networks in the escalation and management of organisational crises. Here, we consider instead informal and unobservable networks. The paper explores how hidden informal exchanges can impact upon organisational decision-making and performance, particularly around inter-agency working, as knowledge distributed across organisations and shared between organisations is often shared through informal means and not captured effectively through the formal decision-making processes. Early warnings and weak signals about potential risks and crises are therefore often missed. We consider the implications of these dynamics in terms of crisis avoidance and crisis management

    From social contract to 'social contrick' : the depoliticisation of economic policy-making under Harold Wilson, 1974–75

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    The 1974-79 Labour Governments were elected on the basis of an agreement with the TUC promising a redistribution of income and wealth known as the Social Contract. However, the Government immediately began to marginalise these commitments in favour of preferences for incomes policy and public expenditure cuts, which has led the Social Contract to be described as the 'Social Contrick'. These changes were legitimised through a process of depoliticisation, and using an Open Marxist framework and evidence from the National Archives, the paper will show that the Treasury's exchange rate strategy and the need to secure external finance placed issues of confidence at the centre of political debate, allowing the Government to argue there was no alternative to the introduction of incomes policy and the reduction of public expenditure

    In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties.

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    Regulated exocytosis of synaptic vesicles is substantially faster than of endocrine dense core vesicles despite similar molecular machineries. The reasons for this difference are unknown and could be due to different regulatory proteins, different spatial arrangements, different vesicle sizes, or other factors. To address these questions, we take a reconstitution approach and compare regulated SNARE-mediated fusion of purified synaptic and dense core chromaffin and insulin vesicles using a single vesicle-supported membrane fusion assay. In all cases, Munc18 and complexin are required to restrict fusion in the absence of calcium. Calcium triggers fusion of all docked vesicles. Munc13 (C1C2MUN domain) is required for synaptic and enhanced insulin vesicle fusion, but not for chromaffin vesicles, correlating inversely with the presence of CAPS protein on purified vesicles. Striking disparities in calcium-triggered fusion rates are observed, increasing with curvature with time constants 0.23 s (synaptic vesicles), 3.3 s (chromaffin vesicles), and 9.1 s (insulin vesicles) and correlating with rate differences in cells
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