Relationship between D90 and D100 with Biochemical and Local Failure in Low-risk Prostate Cancer Treated with Low-rate Brachytherapy (LDR)

Low dose rate brachytherapy (LDR) is an accepted, effective treatment with few local side effects, used as monotherapy in patients with low-risk prostate cancer (PC). The aim of this paper is to analyse 245 patients treated with LDR in the Radiation Oncology Department of the Hospital Gómez Ulla, from 2004 to 2016, evaluating the relationship of dosimetric parameters with biochemical and local recurrence as well as genitourinary and gastrointestinal toxicity derived from the technique. The results obtained show a clear relationship between the dose used and biochemical and local failure

Experimental evaluation of HCFO-1233zd-e as HFC-245fa replacement in an organic rankine cycle system for low temperature heat sources

[EN] In this work an experimental evaluation of the working fluid HCFO-1233zd-E as HFC-245fa replacement in ORC systems for low temperature heat sources has been conducted. A fully monitored ORC module has been used to test both working fluids at different operating conditions. Due to the different densities of the working fluids, the mass flow rate for HCFO-1233zd-E is approximately 20% lower than for HFC-245fa. This causes thermal and electrical powers to be lower for HCF0-1233zd-E than for HFC245fa. However, net electrical efficiency is similar for both working fluids, ranging from 5% to 9.7% in the tested operating conditions. Regarding the expander performance, various performance indicators are addressed. The expander isentropic performance has a maximum value of 75%, with higher values for HCFO-1233zd-E than for HFC-245fa. The overall efficiency of the expander, similar for both working fluids, ranges from 44% to 57% in the experimental test range. (C) 2016 Elsevier Ltd. All rights reserved.The authors thankfully acknowledge the cooperation of Rank (R) for its support in this project.Molés-Ribera, F.; Navarro Esbri, J.; Peris-Pérez, B.; Mota-Babiloni, A. (2016). Experimental evaluation of HCFO-1233zd-e as HFC-245fa replacement in an organic rankine cycle system for low temperature heat sources. Applied Thermal Engineering. 98:954-961. doi:10.1016/j.applthermaleng.2016.01.011S9549619