Dietary flavonoid intake and incidence of erectile dysfunction

Background: The predominant etiology for erectile dysfunction (ED) is vascular, however limited data are available on the role of diet. A higher intake of several flavonoids reduces diabetes and cardiovascular disease (CVD) risk but no studies have examined associations between flavonoids and erectile function.   Objective: To examine the relationship between habitual flavonoid sub-class intakes and incidence of ED.   Methods: We conducted a prospective study among 25,096 men from the Health Professionals Follow-up Study. Total flavonoid and subclass intakes were calculated from food frequency questionnaires collected every 4 years. Participants rated their erectile function in 2000 (with historical reporting from 1986) and again in 2004 and 2008.   Results: During 10 years of follow-up, 35.6% reported incident ED. After multivariate adjustment, including classic CVD risk factors, several sub-classes were associated with reduced ED incidence; specifically flavones (RR 0.91:95%CI=0.85,0.97; p-trend=0.006), flavanones (RR 0.89;95%CI=0.83,0.95; p-trend=0.0009), and anthocyanins (RR 0.91;95%CI=0.85,0.98; p-trend=0.002) comparing extreme intakes. The results remained significant after additional adjustment for a composite dietary intake score. In analyses stratified by age, a higher intake of flavanones, anthocyanins and flavones was significantlyassociated with a reduction in risk of erectile dysfunction only in men <70 years old and not older men (11-16% reduction in risk (p - interaction 0.002, 0.03, 0.007 for flavones, flavanones and anthocyanins respectively). In food-based analysis, higher total fruit intake, major sources of anthocyanins and flavanones, was associated with 14% reduction in risk of ED (RR 0.86;95%CI=0.79,0.92; p=0.002).The American Journal of Clinical Nutrition AJCN/2015/122010 Version 3.    Conclusions : These data suggest that a higher habitual intake of specific 24 flavonoid-rich foods are associated with reduced ED incidence. Intervention trials are needed to further examine the impact of increasing intakes of commonly consumed flavonoid-rich foods on men’s health

Single-color two-photon spectroscopy of Rydberg states in electric fields

Rydberg states of atomic helium with principal quantum numbers ranging from n=20 to n=100 have been prepared by non-resonance-enhanced single-color two-photon excitation from the metastable 2 {^3}S{_1} state. Photoexcitation was carried out using linearly and circularly polarized pulsed laser radiation. In the case of excitation with circularly polarized radiation, Rydberg states with azimuthal quantum number |m_{\ell}|=2 were prepared in zero electric field, and in homogeneous electric fields oriented parallel to the propagation axis of the laser radiation. In sufficiently strong electric fields, individual Rydberg-Stark states were resolved spectroscopically, highlighting the suitability of non-resonance-enhanced multiphoton excitation schemes for the preparation of long-lived high-|m_{\ell}| hydrogenic Rydberg states for deceleration and trapping experiments. Applications of similar schemes for Doppler-free excitation of positronium atoms to Rydberg states are also discussed

Generalized Thermalization in an Integrable Lattice System

After a quench, observables in an integrable system may not relax to the standard thermal values, but can relax to the ones predicted by the generalized Gibbs ensemble (GGE) [M. Rigol et al., Phys. Rev. Lett. 98, 050405 (2007)]. The GGE has been shown to accurately describe observables in various one-dimensional integrable systems, but the origin of its success is not fully understood. Here we introduce a microcanonical version of the GGE and provide a justification of the GGE based on a generalized interpretation of the eigenstate thermalization hypothesis, which was previously introduced to explain thermalization of nonintegrable systems. We study relaxation after a quench of one-dimensional hard-core bosons in an optical lattice. Exact numerical calculations for up to 10 particles on 50 lattice sites (~10^10 eigenstates) validate our approach.Comment: 8 pages, 9 figures, as publishe

Solar wind radiation damage effects in lunar material

The research on solar wind radiation damage and other effects in lunar samples which was conducted to understand the optical properties of lunar materials is reported. Papers presented include: solar radiation effects in lunar samples, albedo of the moon, radiation effects in lunar crystalline rocks, valence states of 3rd transition elements in Apollo 11 and 12 rocks, and trace ferric iron in lunar and meteoritic titanaugites

To Surf and Protect: The Children\u27s Internet Protection Act Policies Material Harmful to Minors and a Whole Lot More

This Note will examine the constitutional issues raised by installing Internet filtering software in public libraries. Part I explores the First Amendment, the standard of review for restricting Internet material, and the government\u27s role in protecting minors and regulating speech. Part II discusses library patrons\u27 First Amendment rights in public libraries. Part III provides the statutory framework of the E-rate and LSTA programs, as well as the Children\u27s Internet Protection Act (CIPA). Part IV examines the effectiveness of current Internet filtering technology and provides the American Library Association\u27s policies on Internet filtering in public libraries. Part V discusses the district court\u27s and the Supreme Court\u27s reasoning in United States v. American Library Associations, Inc. Finally, Part VI analyzes how the Supreme Court erred in failing to hold CIPA unconstitutional

Answers to First Request for Production of Documents

Plaintiff’s First Request for Production of Documents with the State of Ohio\u27s answers included. Requests include the transcript of Dr. Sheppard’s 1954 trial, documents and communications relating to Robert Parks and his attempts to elicit information from Richard Eberling about crimes committed by Eberling, and all documents obtained from Richard Eberling

An Occupational Therapy Guidebook for Individuals with Substance Use Disorder

Individuals with substance use disorder (SUD) experience barriers and challenges that impact their daily occupational performance, engagement, well-being, and quality of life. In addition to disrupting and distorting an individual’s unique occupational outcomes, SUDs can limit, replace, and dictate an individual’s daily meaningful activities, habits, routines, and skills that support healthy occupational engagement. Occupational therapy (OT) practitioners have a unique and valuable role in SUDs treatment as they are equipped to identify these barriers and implement strategies for supportive skill development or restoration. Based on the literature review conducted, OT practitioners do not have an OT practice guideline, protocol, or manualized intervention available to guide OT practice when working with clients with SUDs. The purpose of this capstone project is to address this concern and develop an OT guidebook for OT practitioners working with individuals with SUDs using the theoretical framework of the Model of Human Occupation (MOHO). The methodology of this project consists of three phases: (a) the pre-development phase, (b) the development phase, and (c) the review and revision phase. The guidebook consists of five chapters that supply OT practitioners with recommended best-practice methods to implement the OT process while working with individuals in this client population as well as recommendations for other resources available to the community. The development of this capstone project will expand OT scholarship and practice as well as create a foundation to examine the efficacy of OT in mental health and SUD treatment

Examining Crack Cocaine Sentencing in a Post-Kimbrough World

This article examines Kimbrough’s effect on crack cocaine sentencing. Part I discusses the rise of crack cocaine use in the United States during the 1980s. Part II provides a short history on modern federal sentencing, including the Sentencing Reform Act, the Commission’s Guidelines, and its reports to Congress concerning the 100-to-1 ratio. Part III examines the Supreme Court’s recent Sixth Amendment jurisprudence through its seminal cases, Apprendi and Blakely. In Part IV, this article analyzes the Court’s Booker holding as well as Kimbrough and Gall v. United States, two cases that clarified Booker and its application to crack cocaine cases. Finally, Part V compares the lower courts’ roles after Booker and Kimbrough, suggests that Kimbrough may not be the answer to the crack/powder disparity, and explains why Congress may and should revisit the crack punishment scheme

To Surf and Protect: The Children\u27s Internet Protection Act Policies Material Harmful to Minors and a Whole Lot More

This Note will examine the constitutional issues raised by installing Internet filtering software in public libraries. Part I explores the First Amendment, the standard of review for restricting Internet material, and the government\u27s role in protecting minors and regulating speech. Part II discusses library patrons\u27 First Amendment rights in public libraries. Part III provides the statutory framework of the E-rate and LSTA programs, as well as the Children\u27s Internet Protection Act (CIPA). Part IV examines the effectiveness of current Internet filtering technology and provides the American Library Association\u27s policies on Internet filtering in public libraries. Part V discusses the district court\u27s and the Supreme Court\u27s reasoning in United States v. American Library Associations, Inc. Finally, Part VI analyzes how the Supreme Court erred in failing to hold CIPA unconstitutional

Tannakian approach to linear differential algebraic groups

Tannaka's Theorem states that a linear algebraic group G is determined by the category of finite dimensional G-modules and the forgetful functor. We extend this result to linear differential algebraic groups by introducing a category corresponding to their representations and show how this category determines such a group.Comment: 31 pages; corrected misprint